[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine
C11H18NO4P
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Identification
- CAS Number
- 25383-07-7
- EC Number
- 418-570-8
- UN Number
- 3077
- Index Number
- 015-178-00-5
- PubChem CID
- 57416889
Physical-chemical properties
- Molecular Formula
- C11H18NO4P
- Molar Mass
- 259.24 g/mol
- IUPAC Name
- [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine
Chemical Identifiers
- InChI
- InChI=1S/C8H11N.C3H7O4P/c1-7(9)8-5-3-2-4-6-8;1-2-3(7-2)8(4,5)6/h2-7H,9H2,1H3;2-3H,1H3,(H2,4,5,6)/t7-;2-,3+/m10/s1
- InChI Key
- ODALAXKSIBESFV-PXRNWTNJSA-N
Overview
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine (CAS 25383-07-7) is a chiral phosphonic acid salt compound with epoxide functionality and organic amine components. This specialized organophosphorus compound represents a unique combination of a methyloxirane-substituted phosphonic acid with a phenylethylamine moiety, creating a molecular structure with distinct stereochemical properties. The compound's molecular formula C11H18NO4P and molecular weight of 259.24 g/mol reflect its complex architecture, incorporating both phosphorus-containing acidic groups and nitrogen-containing basic components. The presence of the oxirane ring system provides reactive functionality that distinguishes it from simpler phosphonic acid derivatives. From a safety perspective, this substance is classified under GHS with reproductive toxicity category 2 and aquatic chronic toxicity category 2, requiring careful handling protocols. The warning signal word and associated pictograms GHS08 and GHS09 indicate potential health hazards and environmental concerns. Its ADR class 9 designation classifies it as a miscellaneous dangerous substance for transportation purposes. Industrial applications typically leverage the compound's unique phosphonic acid functionality combined with its chiral properties. The substance finds use in specialized pharmaceutical intermediate synthesis, where its stereochemical precision is valuable for developing enantiomerically pure compounds. Agricultural chemistry applications utilize its phosphonic acid group for crop protection formulations, though with different mechanisms compared to compounds like propan-2-yl N-(3-chlorophenyl)carbamate. Additionally, the compound serves in materials science applications where phosphorus-containing modifiers are required for flame retardancy or surface treatment applications. OYSI provides this technical-grade compound to qualified industrial customers throughout Europe, supporting specialized applications in pharmaceutical, agricultural, and materials science sectors.
Safety & Classification
Repr. 2; Aquatic Chronic 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Toxic to aquatic life with long lasting effects.
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Transport (ADR)
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | (R)-alpha-Phenylethylammonium-(-)-(1R,2S)-(1,2-epoxypropyl)-phosphonat-Monohydrat |
| Marine Pollutant | No |
Frequently Asked Questions
What is [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine is an organophosphorus compound with CAS number 25383-07-7 and molecular formula C11H18NO4P. This substance has a molecular weight of 259.24 g/mol and represents a salt formed between a phosphonic acid derivative containing an epoxide group and phenylethylamine. It is classified as a reproductive toxicant category 2 and presents chronic aquatic toxicity.
What are the physicochemical properties of [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine has a molecular weight of 259.24 g/mol with the formula C11H18NO4P. The compound contains both hydrophilic phosphonic acid groups and hydrophobic aromatic components, suggesting moderate water solubility. As an organophosphorus salt, it likely exists as a solid at room temperature. The presence of the epoxide ring and amine salt structure influences its chemical reactivity and stability properties.
What is [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine used for?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine is primarily used in specialized chemical synthesis and pharmaceutical intermediate applications. The compound's unique structure, containing both phosphonic acid and epoxide functionalities, makes it valuable for organic synthesis reactions. Its stereochemically defined configuration suggests applications in asymmetric synthesis or as a chiral building block in pharmaceutical research and fine chemical manufacturing processes.
How to handle [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine safely?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine requires careful handling due to its reproductive toxicity classification (Repr. 2). Wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume extraction. Avoid inhalation, skin contact, and ingestion. The GHS08 pictogram indicates health hazards, requiring strict adherence to occupational exposure limits and safety procedures during handling and processing.
How to store [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine correctly?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers upright and secure to prevent spillage. Due to its reproductive toxicity classification, store in designated areas with restricted access and appropriate warning labels. Avoid storage near incompatible materials and ensure compliance with local chemical storage regulations.
What to do in case of contact with [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine?
In case of skin contact with [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine, immediately wash the affected area with plenty of soap and water for at least 15 minutes. Remove contaminated clothing. For eye contact, flush immediately with clean water for 15 minutes. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician and provide the safety data sheet.
How to dispose of [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine appropriately?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine must be disposed of as hazardous chemical waste through licensed waste management companies. Do not discharge into drains, soil, or water bodies due to its aquatic chronic toxicity classification (Aquatic Chronic 2). Package waste securely in appropriate containers with proper labeling. Follow local and EU waste regulations (Waste Framework Directive) and obtain waste transfer documentation for disposal tracking.
How to transport [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine is classified as ADR Class 9 (miscellaneous dangerous goods), Packing Group III for transportation purposes. Use appropriate UN-specification packaging with proper labeling and documentation. Transport vehicles must carry appropriate emergency equipment and driver training certification. Follow ADR regulations for loading, segregation, and route planning. Ensure proper shipping papers and emergency response information accompany the shipment during transport across European borders.
Is [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine subject to special regulations?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine is subject to REACH regulation requiring registration for import/manufacture above 1 tonne annually. It is not currently listed as a Substance of Very High Concern (SVHC). The substance falls under CLP regulation for hazard classification and labeling requirements. Its reproductive toxicity classification may trigger additional workplace exposure restrictions and mandatory health surveillance for occupationally exposed workers under EU chemical safety legislation.
Where to buy [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine in Europe?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides comprehensive regulatory documentation, safety data sheets, and technical support for this specialized compound. As a professional chemical distributor, OYSI ensures proper handling, packaging, and transport compliance throughout European markets for research and industrial applications requiring this specific organophosphorus compound.
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ADR Consulting for [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.