[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine
C11H18NO4P
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Identification
- CAS Number
- 25383-07-7
- EC Number
- 418-570-8
- UN Number
- 3077
- Index Number
- 015-178-00-5
- PubChem CID
- 57416889
Physical-chemical properties
- Molecular Formula
- C11H18NO4P
- Molar Mass
- 259.24 g/mol
- IUPAC Name
- [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine
Chemical Identifiers
- InChI
- InChI=1S/C8H11N.C3H7O4P/c1-7(9)8-5-3-2-4-6-8;1-2-3(7-2)8(4,5)6/h2-7H,9H2,1H3;2-3H,1H3,(H2,4,5,6)/t7-;2-,3+/m10/s1
- InChI Key
- ODALAXKSIBESFV-PXRNWTNJSA-N
Overview
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine (CAS 25383-07-7) is a chiral organophosphorus compound salt with epoxide functionality and phosphonic acid properties. This specialized chemical compound represents a unique combination of a phosphonic acid derivative containing a methyloxirane ring and a phenylethylamine salt former. With the molecular formula C11H18NO4P and a molecular weight of 259.24 g/mol, this substance exhibits specific stereochemical properties due to its defined (2R,3S) and (1R) configurations. The presence of both an epoxide ring and phosphonic acid functionality makes it particularly interesting for applications requiring reactive intermediates or specialized catalytic processes. The compound is classified under reproductive toxicity category 2 and aquatic chronic toxicity category 2, requiring careful handling protocols and appropriate safety measures. The GHS08 and GHS09 pictograms indicate both health hazards and environmental concerns, while the ADR class 9 classification designates it as a miscellaneous dangerous substance for transport purposes. These safety characteristics distinguish it from structurally different compounds such as 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione, which belongs to a different chemical class entirely. Primary industrial applications include its use as a pharmaceutical intermediate, particularly in the synthesis of bioactive compounds where stereochemical control is essential. The compound also finds application in specialty polymer chemistry and as a building block for organophosphorus derivatives in agrochemical synthesis. Its unique combination of functional groups makes it valuable for developing chiral auxiliaries and catalysts in asymmetric synthesis processes. OYSI maintains reliable supply chains for this specialized organophosphorus compound, ensuring consistent availability for European industrial customers requiring high-quality chemical intermediates.
Safety & Classification
Repr. 2; Aquatic Chronic 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Toxic to aquatic life with long lasting effects.
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Transport (ADR)
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | (R)-alpha-Phenylethylammonium-(-)-(1R,2S)-(1,2-epoxypropyl)-phosphonat-Monohydrat |
| Marine Pollutant | No |
Frequently Asked Questions
What is [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine is an organophosphorus compound with CAS number 25383-07-7. This substance has a molecular formula of C11H18NO4P and a molar mass of 259.24 g/mol. It contains both phosphonic acid and phenylethylamine functional groups, making it a complex organic molecule with specific stereochemical configurations. The compound is classified as a reproductive toxicant category 2 and poses chronic aquatic toxicity risks.
What are the physicochemical properties of [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine has a molecular weight of 259.24 g/mol and molecular formula C11H18NO4P. The compound contains multiple functional groups including an epoxide ring, phosphonic acid group, and phenylethylamine moiety. Due to the presence of both hydrophilic phosphonic acid and hydrophobic phenyl groups, the substance likely exhibits amphiphilic properties. Specific physical properties such as melting point, boiling point, and solubility data should be obtained from the safety data sheet.
What is [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine used for?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine is primarily used as a chemical intermediate in pharmaceutical and fine chemical synthesis. The compound's unique structure containing both phosphonic acid and chiral amine functionalities makes it valuable for developing specialized pharmaceutical compounds. It may also serve as a building block in the synthesis of bioactive molecules or as a research chemical for academic and industrial laboratories studying organophosphorus chemistry and stereochemistry.
How to handle [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine safely?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine requires careful handling due to its reproductive toxicity classification. Personnel must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin contact, eye contact, and ingestion. The GHS08 pictogram indicates health hazards, so minimize exposure time and follow strict hygiene protocols after handling.
How to store [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine correctly?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly sealed to prevent moisture absorption and contamination. Due to the epoxide functionality, avoid exposure to strong acids or bases that could cause ring-opening reactions. Store away from heat sources and direct sunlight. Implement appropriate segregation from oxidizing agents and ensure storage areas comply with local chemical storage regulations and fire safety requirements.
What to do in case of contact with [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine?
In case of skin contact with [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for at least 15 minutes while holding eyelids open. If inhaled, move the person to fresh air and seek medical attention if breathing difficulties occur. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet for specific first aid measures.
How to dispose of [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine appropriately?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine must be disposed of as hazardous waste through licensed waste disposal contractors. Due to its reproductive toxicity and aquatic toxicity classifications, the substance cannot be disposed of in regular waste streams or sewage systems. Collect waste in appropriate containers, properly labeled with contents and hazard information. Follow local and national waste disposal regulations, including waste tracking documentation. Consider waste minimization strategies and potential recycling or recovery options where technically and economically feasible.
How to transport [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III. This classification requires appropriate packaging, marking, and documentation for transport. Use UN-approved packaging suitable for Class 9 materials and ensure proper hazard labels are affixed. Transport documents must include correct shipping names, UN numbers, and hazard classifications. Drivers must hold appropriate ADR training certificates, and vehicles must comply with Class 9 transport requirements including appropriate equipment and safety measures.
Is [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine subject to specific regulations?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine is subject to REACH registration requirements in the European Union and must comply with CLP classification and labeling regulations. The substance is classified as Repr. 2 (reproductive toxicity category 2) and Aquatic Chronic 2, requiring appropriate hazard communication. It is not currently listed as a Substance of Very High Concern (SVHC). Users must ensure compliance with occupational exposure limits, waste regulations, and transport requirements under ADR Class 9 classification.
Where to buy [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine in Europe?
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to pharmaceutical, research, and industrial customers across Europe with appropriate documentation including safety data sheets and certificates of analysis. As a professional chemical distributor, OYSI ensures compliance with European chemical regulations including REACH and CLP requirements. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements.
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[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;(1R)-1-phenylethanamine is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.