4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide

C13H21NOSSi

CAS175217-20-6
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
175217-20-6
UN Number
3077
Index Number
616-233-00-1
PubChem CID
9881821

Physical-chemical properties

Molecular Formula
C13H21NOSSi
Molar Mass
267.46 g/mol
IUPAC Name
4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide

Chemical Identifiers

InChI
InChI=1S/C13H21NOSSi/c1-7-8-14-12(15)11-9(2)10(3)16-13(11)17(4,5)6/h7H,1,8H2,2-6H3,(H,14,15)
InChI Key
MXMXHPPIGKYTAR-UHFFFAOYSA-N

Overview

4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide (CAS 175217-20-6) is an organosilicon thiophene derivative with carboxamide functionality and trimethylsilyl substitution. This specialized organosilicon compound represents an important class of heterocyclic molecules that combine the unique properties of thiophene rings with silyl functionality. The molecular structure features a thiophene core substituted with two methyl groups at positions 4 and 5, a trimethylsilyl group at position 2, and a prop-2-enyl carboxamide substituent at position 3. With a molecular formula of C13H21NOSSi and molecular weight of 267.46 g/mol, this compound exhibits the characteristic properties of both organosilicon and thiophene chemistry. The compound is classified under GHS with warning-level hazards, specifically STOT RE 2 (Specific Target Organ Toxicity Repeated Exposure Category 2) and Aquatic Chronic 2, indicated by GHS08 and GHS09 pictograms. These classifications require appropriate handling procedures and environmental considerations during industrial use. The ADR Class 9 designation categorizes it as a miscellaneous dangerous substance for transportation purposes. Industrial applications typically include use as an advanced intermediate in pharmaceutical synthesis, specialty polymer manufacturing, and materials science research where organosilicon thiophene derivatives provide unique electronic and structural properties. The compound may also serve in applications similar to other specialty carboxamides, though distinct from simpler structures like propan-2-yl N-(3-chlorophenyl)carbamate which lacks the sophisticated thiophene-silyl architecture. OYSI maintains reliable supply chains for this technical-grade organosilicon compound, supporting European industrial customers with consistent quality and regulatory compliance.

Safety & Classification

Warning
Classification:

STOT RE 2; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H373

May cause damage to organs through prolonged or repeated exposure.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameSilthiofam (ISO)
Marine PollutantNo

Frequently Asked Questions

What is 4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide?

4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide is an organosilicon compound with the molecular formula C13H21NOSSi and CAS number 175217-20-6. This specialized chemical features a thiophene ring structure substituted with dimethyl groups, a trimethylsilyl group, and an allyl carboxamide functionality. With a molecular weight of 267.46 g/mol, it belongs to the class of silyl-substituted heterocyclic compounds used in advanced chemical synthesis applications.

What are the physicochemical properties of 4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide?

4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide is a compound with molecular formula C13H21NOSSi and molecular weight 267.46 g/mol. As an organosilicon thiophene derivative, it typically exists as a solid or viscous liquid at room temperature. The presence of the trimethylsilyl group imparts hydrophobic characteristics, while the carboxamide functionality may provide some polarity. The compound's physical appearance and exact solubility parameters depend on purity and specific formulation conditions.

What is 4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide used for?

4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide is primarily used as an intermediate in organic synthesis and pharmaceutical research. Its unique structure combining thiophene, silyl, and carboxamide functionalities makes it valuable for developing new materials, agrochemicals, and bioactive compounds. The trimethylsilyl group serves as a protecting group in multi-step syntheses, while the thiophene core provides electronic properties useful in materials science applications and drug discovery programs.

How to handle 4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide safely?

4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide requires careful handling due to its STOT RE 2 classification. Always wear appropriate personal protective equipment including safety glasses, chemical-resistant gloves, and lab coat. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid direct skin and eye contact. The GHS08 pictogram indicates potential health hazards requiring specific organ toxicity precautions. Follow all safety data sheet recommendations and workplace safety protocols during use.

How to store 4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide correctly?

4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. As an organosilicon compound, protect from moisture and extreme temperatures. Store away from strong oxidizing agents and sources of ignition. Maintain storage temperatures according to supplier specifications and ensure containers are properly labeled with hazard information. Keep away from environmental release points due to its Aquatic Chronic 2 classification.

What to do in case of contact with 4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide?

Immediate action is required upon contact with 4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. In case of eye contact, rinse immediately with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention. Always consult the safety data sheet for specific first aid measures and contact poison control if necessary.

How to dispose of 4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide properly?

4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide must be disposed of according to local, national, and international waste regulations. Due to its Aquatic Chronic 2 classification, prevent environmental release and dispose through licensed hazardous waste contractors. Do not discharge to sewers, waterways, or soil. Small laboratory quantities may require specialized chemical waste collection. Container disposal should follow local regulations for chemical packaging. Always consult current waste disposal regulations and environmental authorities for specific requirements in your jurisdiction.

How to transport 4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide?

4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide is classified as ADR Class 9, Packing Group III for transport purposes. This classification indicates it's a miscellaneous dangerous substance with relatively lower risk during transport. Proper packaging, labeling, and documentation according to ADR regulations are required. Use approved packaging materials and ensure proper hazard markings are displayed. Transport vehicles must comply with Class 9 dangerous goods requirements. Always verify current transport regulations and work with qualified dangerous goods handlers.

Is 4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide subject to specific regulations?

4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide is subject to standard chemical regulations including REACH registration requirements in Europe and CLP classification as STOT RE 2 and Aquatic Chronic 2. The compound is not listed as a Substance of Very High Concern (SVHC). Users must comply with occupational health and safety regulations, environmental protection laws, and transport regulations (ADR Class 9). Import/export may require additional documentation depending on jurisdiction and end-use applications.

Where to buy 4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide in Europe?

4,5-dimethyl-N-prop-2-enyl-2-trimethylsilylthiophene-3-carboxamide is available through OYSI, a specialized European distributor of fine chemicals and intermediates. As a professional chemical supplier, OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance for European markets. Contact OYSI directly for availability, specifications, packaging options, and technical support. Other specialized chemical distributors may also carry this product, but verify supplier credentials and product quality certifications before purchasing.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.