2,3-dichloroquinoxaline-6-carbonyl chloride

2,3-dichloroquinoxaline-6-carbonyl chloride is an organic chemical compound with the molecular formula C9H3Cl3N2O and CAS number 1919-43-3. This compound belongs to the quinoxaline family and features both dichloroquinoxaline and carbonyl chloride functional groups. With a molecular weight of 261.5 g/mol, it serves as an important intermediate in pharmaceutical and chemical synthesis applications.

2,3-dichloroquinoxaline-6-carbonyl chloride is a crystalline solid compound containing three chlorine atoms and reactive carbonyl chloride functionality. The compound exhibits typical properties of acid chlorides, being moisture-sensitive and reactive toward nucleophiles. Due to the carbonyl chloride group, it readily hydrolyzes in the presence of water, forming the corresponding carboxylic acid and releasing hydrogen chloride gas.

2,3-dichloroquinoxaline-6-carbonyl chloride is primarily used as a chemical intermediate in pharmaceutical synthesis and organic chemistry research. The compound serves as a key building block for developing quinoxaline-based pharmaceuticals and agrochemicals. Its reactive carbonyl chloride group makes it valuable for acylation reactions and the formation of amide bonds in medicinal chemistry applications.

2,3-dichloroquinoxaline-6-carbonyl chloride must be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in a well-ventilated area or under a fume hood due to potential hydrogen chloride release upon moisture contact. Avoid contact with skin, eyes, and clothing, and ensure proper ventilation to prevent inhalation of vapors or dust.

2,3-dichloroquinoxaline-6-carbonyl chloride should be stored in a cool, dry place away from moisture and humidity. Keep containers tightly sealed and protect from direct sunlight and heat sources. The compound must be stored separately from water, alcohols, amines, and other nucleophilic substances that can react with the carbonyl chloride group. Use appropriate secondary containment to prevent environmental release.

In case of skin contact with 2,3-dichloroquinoxaline-6-carbonyl chloride, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention.

2,3-dichloroquinoxaline-6-carbonyl chloride must be disposed of according to local and national hazardous waste regulations. The compound should not be discharged into drains, soil, or water bodies. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may be carefully hydrolyzed under controlled conditions by qualified personnel before neutralization and disposal as chemical waste.

2,3-dichloroquinoxaline-6-carbonyl chloride is classified under ADR Class 8 (corrosive substances) with Packing Group II for transportation purposes. It must be packaged in appropriate UN-approved containers and labeled according to dangerous goods regulations. Transport vehicles must carry proper documentation, emergency response information, and comply with routing restrictions. Only trained personnel should handle the transportation of this regulated chemical substance.

2,3-dichloroquinoxaline-6-carbonyl chloride is subject to standard chemical regulations including REACH registration requirements in the European Union. The compound is not classified as a Substance of Very High Concern (SVHC) under current regulations. However, users must comply with local chemical safety laws, workplace safety regulations, and proper classification, labeling, and packaging requirements according to CLP regulation.

2,3-dichloroquinoxaline-6-carbonyl chloride is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to pharmaceutical, research, and chemical manufacturing industries across Europe. As a professional chemical supplier, OYSI ensures proper documentation, quality standards, and regulatory compliance for all chemical products including specialized intermediates like 2,3-dichloroquinoxaline-6-carbonyl chloride.