2-ethoxy-3,4-dihydro-2H-pyran
C7H12O2
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Identification
- CAS Number
- 103-75-3
- EC Number
- 203-141-8
- UN Number
- 1993
- PubChem CID
- 7676
Physical-chemical properties
- Molecular Formula
- C7H12O2
- Molar Mass
- 128.17 g/mol
- IUPAC Name
- 2-ethoxy-3,4-dihydro-2H-pyran
Chemical Identifiers
- InChI
- InChI=1S/C7H12O2/c1-2-8-7-5-3-4-6-9-7/h4,6-7H,2-3,5H2,1H3
- InChI Key
- VZJFPIXCMVSTID-UHFFFAOYSA-N
Overview
2-ethoxy-3,4-dihydro-2H-pyran (CAS 103-75-3) is a cyclic ether compound with protective group functionality widely used in organic synthesis applications. This specialized chemical compound belongs to the dihydropyran family and serves as an important building block in pharmaceutical and fine chemical manufacturing. With its molecular formula C7H12O2 and molecular weight of 128.17 g/mol, 2-ethoxy-3,4-dihydro-2H-pyran exhibits unique reactivity patterns that make it valuable for specific synthetic transformations. The compound is classified under ADR transport class 3, indicating its flammable nature, though it presents no specific GHS hazard classifications under normal handling conditions. The ethoxy substitution at the 2-position of the dihydropyran ring system provides distinct chemical properties compared to related compounds in this chemical family. Unlike simpler derivatives such as 2-ethylbutyl acetate, this compound offers specific protecting group capabilities that are essential in multi-step synthetic procedures. Its cyclic structure and ether functionality enable selective reactions while maintaining stability under controlled conditions. In industrial applications, 2-ethoxy-3,4-dihydro-2H-pyran finds primary use as a protecting group reagent in pharmaceutical intermediate synthesis, particularly for alcohol and amine protection during complex molecule construction. The compound also serves as a synthetic intermediate in specialty chemical production and as a reagent in academic research laboratories focusing on organic methodology development. Its compatibility with various reaction conditions makes it suitable for both batch and continuous manufacturing processes. OYSI maintains reliable supply channels for 2-ethoxy-3,4-dihydro-2H-pyran to support European chemical manufacturers and research institutions requiring this specialized synthetic building block.
Safety & Classification
No Hazard Classification
This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.
Transport (ADR)
| UN Number | 1993 |
| ADR Class | 3 |
| Packing Group | III |
| Tunnel Code | D/E |
| Proper Shipping Name | 2-Ethoxy-3,4-dihydro-2H-pyran |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-ethoxy-3,4-dihydro-2H-pyran?
2-ethoxy-3,4-dihydro-2H-pyran is an organic compound with the molecular formula C7H12O2 and CAS number 103-75-3. It belongs to the pyran family, featuring a six-membered ring containing one oxygen atom. This compound has a molecular weight of 128.17 g/mol and is characterized by an ethoxy group attached to the dihydropyran ring structure. It is commonly used as an intermediate in organic synthesis and chemical manufacturing processes.
What are the physicochemical properties of 2-ethoxy-3,4-dihydro-2H-pyran?
2-ethoxy-3,4-dihydro-2H-pyran is a colorless to pale yellow liquid at room temperature with a characteristic ether-like odor. The compound has a molecular weight of 128.17 g/mol and contains both ether and cyclic structural elements. It exhibits moderate volatility and is soluble in organic solvents such as alcohols, ethers, and hydrocarbons. The presence of the ethoxy group influences its polarity and solubility characteristics in various chemical systems.
What is 2-ethoxy-3,4-dihydro-2H-pyran used for?
2-ethoxy-3,4-dihydro-2H-pyran is primarily used as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a building block for the production of more complex organic molecules and can be employed in the synthesis of various pharmaceutical compounds. The compound is also utilized in specialty chemical manufacturing, research and development applications, and as a reagent in laboratory synthesis procedures where pyran derivatives are required.
How to handle 2-ethoxy-3,4-dihydro-2H-pyran safely?
2-ethoxy-3,4-dihydro-2H-pyran should be handled with standard laboratory safety precautions despite having no specific GHS classifications. Wear appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and laboratory coats. Work in well-ventilated areas or under fume hoods to avoid inhalation of vapors. Avoid contact with skin, eyes, and clothing. Use proper handling techniques for organic solvents and ensure all equipment is properly grounded to prevent static discharge.
How to store 2-ethoxy-3,4-dihydro-2H-pyran correctly?
2-ethoxy-3,4-dihydro-2H-pyran should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and ignition sources. Keep containers away from direct sunlight and maintain storage temperatures below 25°C when possible. Store separately from strong oxidizing agents and acids. Ensure storage areas comply with local fire safety regulations for flammable liquids, and regularly inspect containers for leaks or deterioration.
What to do in case of contact with 2-ethoxy-3,4-dihydro-2H-pyran?
In case of skin contact with 2-ethoxy-3,4-dihydro-2H-pyran, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If eye contact occurs, flush eyes with clean water for at least 15 minutes and seek medical attention. In case of inhalation, move the person to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for specific emergency procedures.
How to dispose of 2-ethoxy-3,4-dihydro-2H-pyran appropriately?
2-ethoxy-3,4-dihydro-2H-pyran must be disposed of in accordance with local, national, and international waste regulations. The compound should be treated as organic chemical waste and disposed of through licensed waste management companies. Do not pour down drains or release into the environment. Small quantities may be suitable for incineration at appropriate high-temperature facilities. Always consult local environmental authorities and waste management regulations before disposal.
How to transport 2-ethoxy-3,4-dihydro-2H-pyran?
2-ethoxy-3,4-dihydro-2H-pyran is classified under ADR Class 3 (flammable liquids), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods transportation regulations. Shipments must comply with ADR/RID requirements for road and rail transport within Europe. Proper shipping names, hazard labels, and transport documents are mandatory. Vehicles must be equipped according to flammable liquid transport regulations.
Is 2-ethoxy-3,4-dihydro-2H-pyran subject to specific regulations?
2-ethoxy-3,4-dihydro-2H-pyran is not classified as a Substance of Very High Concern (SVHC) under REACH regulations and has no specific GHS hazard classifications. However, it remains subject to general REACH registration requirements if imported or manufactured in quantities above one tonne per year. Standard chemical safety assessments and documentation requirements apply. Transport regulations under ADR Class 3 must be followed, and local workplace safety regulations regarding chemical handling apply.
Where to buy 2-ethoxy-3,4-dihydro-2H-pyran in Europe?
2-ethoxy-3,4-dihydro-2H-pyran is available through OYSI, a European distributor of specialty chemicals and intermediates. OYSI provides reliable supply chains across Europe with appropriate documentation, safety data sheets, and regulatory compliance support. As a professional chemical distributor, OYSI ensures proper packaging, transportation compliance, and technical support for industrial customers requiring this compound for synthesis and manufacturing applications throughout the European market.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.