2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone
C8H16NO4PS2
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Identification
- CAS Number
- 144-41-2
- EC Number
- 205-628-0
- UN Number
- 2783
- Index Number
- 015-058-00-2
- PubChem CID
- 8952
Physical-chemical properties
- Molecular Formula
- C8H16NO4PS2
- Molar Mass
- 285.30 g/mol
- IUPAC Name
- 2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone
Chemical Identifiers
- InChI
- InChI=1S/C8H16NO4PS2/c1-11-14(15,12-2)16-7-8(10)9-3-5-13-6-4-9/h3-7H2,1-2H3
- InChI Key
- NTHGWXIWFHGPLK-UHFFFAOYSA-N
Overview
2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone (CAS 144-41-2) is an organophosphorus compound with high acute toxicity and significant aquatic environmental hazard potential. This specialized organophosphorus chemical, with the molecular formula C8H16NO4PS2 and a molecular weight of 285.3 g/mol, represents a complex compound containing both phosphorus-sulfur bonds and a morpholine moiety. The presence of dimethoxyphosphinothioyl and morpholinyl functional groups gives this substance unique chemical properties that make it valuable in specific industrial applications, though its high toxicity profile requires careful handling protocols. The compound exhibits significant safety concerns, classified under multiple Acute Toxicity Category 3 classifications and carrying the "Danger" signal word with GHS06 (skull and crossbones) and GHS09 (environmental hazard) pictograms. Its classification as Aquatic Acute 1 and Aquatic Chronic 1 indicates severe toxicity to aquatic organisms with long-lasting effects, necessitating strict environmental protection measures during handling and disposal. Transportation falls under ADR Class 6.1, reflecting its toxic nature and requiring specialized logistics protocols. In industrial applications, this organophosphorus compound finds use primarily in agricultural chemical synthesis, particularly as an intermediate in pesticide formulation processes. It also serves specialized roles in pharmaceutical intermediate synthesis and as a reagent in organophosphorus chemistry research. Unlike simpler compounds such as propanedinitrile, this molecule's complex structure provides specific reactivity patterns valuable in advanced chemical manufacturing processes. The compound's morpholine ring system contributes to its solubility characteristics and biological activity profile, distinguishing it from other organophosphorus compounds in terms of both efficacy and safety considerations. OYSI maintains reliable supply chains for this specialized chemical, ensuring consistent availability for qualified industrial customers requiring high-purity organophosphorus intermediates.
Safety & Classification
Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2783 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | Morphothion (ISO) |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone?
2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone is an organophosphorus compound with the molecular formula C8H16NO4PS2 and CAS number 144-41-2. This chemical substance has a molecular weight of 285.3 g/mol and contains both phosphorus and sulfur functional groups along with a morpholine ring. It is classified as a highly toxic substance with significant environmental hazards, requiring careful handling and specialized safety measures in industrial applications.
What are the physicochemical properties of 2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone?
2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone is an organophosphorus compound with a molecular weight of 285.3 g/mol and the molecular formula C8H16NO4PS2. The substance contains phosphinothioyl and morpholine functional groups, contributing to its chemical reactivity. Specific physical properties such as melting point, boiling point, and solubility data would require detailed technical specifications from the manufacturer or supplier for precise handling and application requirements.
What is 2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone used for?
2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone is primarily used as a specialized chemical intermediate in organic synthesis and pharmaceutical research. Its organophosphorus structure makes it valuable in the development of bioactive compounds and agrochemical products. The presence of morpholine and phosphinothioyl groups provides specific reactivity patterns useful in chemical manufacturing processes. However, its high toxicity classification limits its use to professional industrial applications with appropriate safety controls.
How to handle 2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone safely?
2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone must be handled with extreme caution due to its Acute Toxicity Category 3 classification. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. The substance displays GHS06 (skull and crossbones) and GHS09 (environmental hazard) pictograms, indicating both human health and environmental risks requiring specialized handling procedures.
How to store 2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone correctly?
2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Use original containers with secure closures and clear labeling. Given its high toxicity and environmental hazard classification, storage areas must be restricted to authorized personnel only. Implement secondary containment measures to prevent environmental release. Regular inventory checks and temperature monitoring help maintain product integrity and safety compliance.
What to do in case of contact with 2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone?
Immediate action is required upon contact with 2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone due to its high toxicity. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with water for 15 minutes while holding eyelids open. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always contact emergency services and provide the safety data sheet to medical personnel.
How to dispose of 2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone appropriately?
2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone must be disposed of through licensed hazardous waste disposal facilities due to its toxic and environmentally hazardous properties. The substance cannot be discharged into sewers, waterways, or regular waste streams. Contact certified waste management companies experienced in handling organophosphorus compounds. Maintain detailed disposal records and ensure compliance with local, national, and EU waste regulations. Empty containers should also be treated as hazardous waste and disposed of accordingly.
How to transport 2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone?
2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Transportation must be conducted by certified carriers experienced in handling toxic chemicals. Proper shipping papers, emergency response information, and hazard placards are mandatory. Vehicles must carry appropriate emergency equipment and follow designated routing restrictions for hazardous materials transport.
Is 2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone subject to specific regulations?
2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone is subject to multiple regulatory frameworks including REACH registration requirements for chemical substances in the EU. The compound falls under CLP regulation for classification, labeling, and packaging due to its acute toxicity and environmental hazard properties. While not currently listed as a SVHC (Substance of Very High Concern), its toxicity profile may trigger additional reporting obligations. Companies handling this substance must ensure compliance with occupational safety regulations and environmental protection laws.
Where to buy 2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone in Europe?
2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone can be purchased through OYSI, a specialized European distributor of technical chemical products. OYSI provides access to this highly regulated substance for qualified industrial customers with appropriate handling capabilities and regulatory compliance. Given the substance's toxicity classification and regulatory requirements, suppliers typically require documentation of intended use, safety protocols, and waste disposal arrangements before processing orders. Contact OYSI directly for availability, technical specifications, and regulatory support.
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2-dimethoxyphosphinothioylsulfanyl-1-morpholin-4-ylethanone is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.