2-(4-chloro-2-nitroanilino)ethanol

2-(4-chloro-2-nitroanilino)ethanol is an organic chemical compound with the molecular formula C8H9ClN2O3 and CAS number 59320-13-7. This substance belongs to the class of substituted anilines, featuring both chloro and nitro substituents on the benzene ring along with an ethanol group. With a molecular weight of 216.62 g/mol, it is classified as moderately hazardous under GHS regulations, requiring careful handling due to its acute toxicity and environmental impact potential.

2-(4-chloro-2-nitroanilino)ethanol is a solid organic compound at room temperature, typically appearing as a crystalline powder. The presence of the ethanol group (-CH2CH2OH) provides some water solubility, while the aromatic ring system contributes to its stability. The compound contains both electron-withdrawing groups (nitro and chloro) and a polar hydroxyl group, affecting its solubility profile and reactivity. Its molecular structure suggests moderate polarity with potential for hydrogen bonding through the hydroxyl group.

2-(4-chloro-2-nitroanilino)ethanol is primarily used as an intermediate in organic synthesis and pharmaceutical research. Its unique structure containing both electron-withdrawing substituents and a hydroxyl group makes it valuable for developing specialized chemical compounds. The substance may serve as a building block in the synthesis of more complex molecules, particularly in medicinal chemistry applications. Its specific substitution pattern allows for selective chemical modifications in multi-step synthetic processes.

2-(4-chloro-2-nitroanilino)ethanol requires careful handling due to its Acute Tox. 4 classification. Essential safety measures include wearing appropriate personal protective equipment such as chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume extraction systems. Avoid skin contact, inhalation, and ingestion. The GHS07 warning pictogram indicates the need for standard laboratory safety precautions. Always consult the safety data sheet before handling and ensure proper training of personnel.

2-(4-chloro-2-nitroanilino)ethanol should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly closed and protected from light to prevent degradation. Store in appropriate secondary containment to prevent environmental release, considering its Aquatic Chronic 2 classification. Maintain storage temperatures below 25°C when possible. Ensure storage areas are equipped with spill containment measures and keep away from sources of ignition, strong oxidizers, and reactive chemicals that could interact with the nitro or chloro substituents.

Immediate action is required upon contact with 2-(4-chloro-2-nitroanilino)ethanol due to its acute toxicity. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention immediately. Always consult the specific safety data sheet for detailed first aid measures and contact emergency services if symptoms develop.

2-(4-chloro-2-nitroanilino)ethanol must be disposed of through authorized hazardous waste management systems due to its toxicity and environmental impact classification. The substance cannot be disposed of via normal waste streams or sewage systems. Contact licensed waste disposal companies specializing in chemical waste treatment. Ensure proper documentation and waste classification codes are provided. Small quantities may require incineration at high temperatures in specialized facilities. Always comply with local, national, and EU waste regulations, including the Waste Framework Directive requirements.

2-(4-chloro-2-nitroanilino)ethanol is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transport purposes. This classification requires appropriate UN-approved packaging, proper labeling with Class 9 hazard labels, and transport documentation. Packages must be marked with the correct shipping name and UN number. Transport vehicles should carry appropriate emergency equipment and drivers must have ADR training certification. Ensure compliance with quantity limitations and segregation requirements during transport across European borders.

2-(4-chloro-2-nitroanilino)ethanol is subject to standard EU chemical regulations including REACH registration requirements and CLP classification obligations. The substance is currently not listed as an SVHC (Substance of Very High Concern) under REACH. However, its Acute Tox. 4 and Aquatic Chronic 2 classifications require compliance with GHS labeling requirements including Warning signal word and appropriate pictograms (GHS07, GHS09). Users must ensure proper risk assessments, exposure scenarios, and workplace safety measures are implemented according to EU occupational safety directives.

2-(4-chloro-2-nitroanilino)ethanol is available through specialized chemical distributors in Europe, including OYSI, which serves as a reliable European supplier of technical chemical products. OYSI provides properly classified and documented chemical substances with appropriate safety data sheets and regulatory compliance documentation. When sourcing this compound, ensure the supplier can provide proper transport documentation, ADR compliance, and quality certificates. Contact OYSI's technical sales team for availability, specifications, and regulatory support for your specific application requirements.