2-(4-chloro-2-nitroanilino)ethanol

C8H9ClN2O3

CAS59320-13-7
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
59320-13-7
EC Number
413-280-8
UN Number
3077
Index Number
609-063-00-4
PubChem CID
5182864

Physical-chemical properties

Molecular Formula
C8H9ClN2O3
Molar Mass
216.62 g/mol
IUPAC Name
2-(4-chloro-2-nitroanilino)ethanol

Chemical Identifiers

InChI
InChI=1S/C8H9ClN2O3/c9-6-1-2-7(10-3-4-12)8(5-6)11(13)14/h1-2,5,10,12H,3-4H2
InChI Key
LGGKGPQFSCBUOR-UHFFFAOYSA-N

Overview

2-(4-chloro-2-nitroanilino)ethanol (CAS 59320-13-7) is an aromatic amine compound featuring chlorine and nitro substituents with moderate toxicity properties. This specialized chemical intermediate belongs to the family of substituted aniline derivatives, characterized by its unique combination of functional groups including an ethanol moiety, a chlorine atom, and a nitro group positioned on the aromatic ring. The molecular structure C8H9ClN2O3 provides specific reactivity patterns that make it valuable in various synthetic applications. With a molecular weight of 216.62 g/mol, this compound exhibits properties typical of halogenated nitroanilines while offering additional functionality through its ethanol substituent. The compound presents moderate safety considerations, classified under GHS07 and GHS09 pictograms with a "Warning" signal word. Its Acute Toxicity 4 classification requires appropriate handling procedures, while its Aquatic Chronic 2 designation indicates potential environmental persistence requiring careful disposal protocols. Transportation falls under ADR Class 9, reflecting its status as a miscellaneous dangerous substance requiring specialized handling during shipping and storage. Primary industrial applications include its use as a chemical intermediate in pharmaceutical synthesis, dye manufacturing, and specialized organic chemistry processes. The compound's unique substitution pattern makes it particularly valuable in developing compounds with specific biological or chemical properties. Related compounds in industrial applications include diethyl 2-[(4-ethoxyanilino)methylidene]propanedioate, which shares similar aniline-based functionality, and 4-(4,4-dimethyl-3-oxopyrazolidin-1-yl)benzoic acid, used in comparable synthetic pathways. OYSI maintains reliable access to 2-(4-chloro-2-nitroanilino)ethanol through our established European supply network, ensuring consistent availability for industrial and research applications.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name2-[(4-Chlor-2-nitrophenyl)amino]ethanol
Marine PollutantNo

Frequently Asked Questions

What is 2-(4-chloro-2-nitroanilino)ethanol?

2-(4-chloro-2-nitroanilino)ethanol is an organic chemical compound with the molecular formula C8H9ClN2O3 and CAS number 59320-13-7. This substance belongs to the family of substituted anilines, featuring both chloro and nitro substituents on the aromatic ring along with an ethanol side chain. With a molecular weight of 216.62 g/mol, it is classified as a hazardous chemical requiring appropriate safety measures during handling and storage.

What are the physicochemical properties of 2-(4-chloro-2-nitroanilino)ethanol?

2-(4-chloro-2-nitroanilino)ethanol is an organic compound with a molecular weight of 216.62 g/mol and the molecular formula C8H9ClN2O3. As a substituted aniline derivative containing both polar (hydroxyl, nitro) and nonpolar (aromatic, chloro) groups, it likely exhibits moderate solubility in polar solvents. The presence of the nitro group typically imparts a yellowish coloration to such compounds. Specific physical properties such as melting point, boiling point, and exact solubility data would require detailed technical specification sheets.

What is 2-(4-chloro-2-nitroanilino)ethanol used for?

2-(4-chloro-2-nitroanilino)ethanol is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its structure, containing both aniline and ethanol functionalities with chloro and nitro substituents, makes it valuable for producing more complex molecules through various chemical transformations. It may serve as a building block in the synthesis of dyes, pharmaceuticals, or other specialty chemicals. The compound's specific applications depend on its reactivity profile and the target molecules being synthesized.

How to handle 2-(4-chloro-2-nitroanilino)ethanol safely?

2-(4-chloro-2-nitroanilino)ethanol must be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and lab coats. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Given its Acute Tox. 4 classification, avoid skin contact and ingestion. Use non-sparking tools and ground equipment to prevent static buildup. Ensure emergency eyewash and shower facilities are readily accessible, and maintain good hygiene practices throughout handling procedures.

How to store 2-(4-chloro-2-nitroanilino)ethanol correctly?

2-(4-chloro-2-nitroanilino)ethanol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers upright and properly labeled with hazard information. Due to its chemical structure, avoid storage near strong oxidizing agents, acids, or bases that could cause unwanted reactions. Implement appropriate containment measures to prevent environmental release, considering its Aquatic Chronic 2 classification. Regular inspection of containers for damage or leakage is recommended.

What to do in case of contact with 2-(4-chloro-2-nitroanilino)ethanol?

In case of skin contact with 2-(4-chloro-2-nitroanilino)ethanol, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move the person to fresh air and keep them at rest. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a poison control center or physician for specific medical advice.

How to dispose of 2-(4-chloro-2-nitroanilino)ethanol properly?

2-(4-chloro-2-nitroanilino)ethanol must be disposed of through licensed hazardous waste disposal facilities in accordance with local, national, and EU regulations. Do not discharge into drains, waterways, or soil due to its Aquatic Chronic 2 classification. Small laboratory quantities should be collected in appropriate waste containers and labeled clearly. Incineration at authorized facilities capable of handling chlorinated organic compounds may be required. Always consult with waste management specialists and regulatory authorities for specific disposal requirements in your jurisdiction.

How to transport 2-(4-chloro-2-nitroanilino)ethanol?

2-(4-chloro-2-nitroanilino)ethanol is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. This classification indicates it presents a relatively lower degree of danger during transport compared to higher packing groups. Packages must be properly labeled with appropriate hazard markings and accompanied by relevant transport documentation. Use UN-approved packaging suitable for Packing Group III substances. Ensure vehicles are properly placarded and drivers hold appropriate dangerous goods training certifications.

Is 2-(4-chloro-2-nitroanilino)ethanol subject to specific regulations?

2-(4-chloro-2-nitroanilino)ethanol is subject to standard EU chemical regulations including REACH and CLP classifications but is not currently listed as a Substance of Very High Concern (SVHC). It must be handled according to its harmonized classification as Acute Tox. 4 and Aquatic Chronic 2, requiring appropriate risk management measures. Users must comply with workplace exposure limits, environmental discharge restrictions, and proper waste disposal regulations. Regular safety data sheet updates and risk assessments are mandatory under REACH requirements.

Where to buy 2-(4-chloro-2-nitroanilino)ethanol in Europe?

2-(4-chloro-2-nitroanilino)ethanol is available through OYSI, a specialized European distributor of technical chemicals and laboratory reagents. OYSI provides high-quality chemical products with proper documentation including safety data sheets and certificates of analysis. As a European-based supplier, OYSI ensures compliance with EU regulations and provides reliable supply chain management for industrial and research applications. Contact OYSI directly for availability, specifications, packaging options, and delivery throughout European markets.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.