2-chloro-6-(trichloromethyl)pyridine

2-chloro-6-(trichloromethyl)pyridine is a chlorinated pyridine derivative with the molecular formula C6H3Cl4N and CAS number 1929-82-4. This organic compound features a pyridine ring substituted with a chlorine atom at position 2 and a trichloromethyl group at position 6. With a molecular weight of 230.9 g/mol, it belongs to the family of halogenated heterocyclic compounds and is classified as moderately hazardous with acute toxicity and aquatic toxicity properties.

2-chloro-6-(trichloromethyl)pyridine is typically a solid crystalline compound at room temperature due to its molecular structure and multiple chlorine substitutions. The presence of four chlorine atoms significantly increases its molecular weight and affects its physical properties. As a chlorinated pyridine derivative, it likely exhibits limited water solubility but good solubility in organic solvents. The compound may have a characteristic chemical odor typical of chlorinated aromatic compounds.

2-chloro-6-(trichloromethyl)pyridine is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its unique substitution pattern makes it valuable for developing agrochemicals, pharmaceuticals, and specialty chemicals. The compound serves as a building block for more complex molecules, particularly in the synthesis of pyridine-based active ingredients. It may also find applications in research and development of new chemical entities requiring specific chlorinated pyridine structures.

2-chloro-6-(trichloromethyl)pyridine requires careful handling due to its Acute Tox. 4 classification. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation exposure. Prevent skin and eye contact, and avoid ingestion. Use appropriate measuring and transfer equipment to minimize direct handling. Ensure emergency shower and eyewash stations are accessible, and follow established laboratory safety protocols for hazardous chemicals.

2-chloro-6-(trichloromethyl)pyridine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers upright and properly labeled with hazard information. Store separately from incompatible materials such as strong oxidizing agents, strong bases, and reactive metals. Maintain storage temperatures within recommended ranges and ensure storage areas are equipped with appropriate spill containment measures. Regular container inspection is recommended to prevent leaks.

2-chloro-6-(trichloromethyl)pyridine exposure requires immediate first aid measures. For skin contact, immediately remove contaminated clothing and wash affected area with plenty of soap and water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for 15-20 minutes and remove contact lenses if easily removable. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult a physician after any significant exposure.

2-chloro-6-(trichloromethyl)pyridine must be disposed of as hazardous waste according to local and national environmental regulations. Do not discharge into drains, waterways, or soil due to its aquatic toxicity classification. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small laboratory quantities may require special collection procedures. Maintain disposal records and certificates as required by regulations. Empty containers should also be treated as hazardous waste unless properly decontaminated according to regulatory standards.

2-chloro-6-(trichloromethyl)pyridine is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Packages must bear appropriate hazard labels and shipping documentation must include proper shipping names and classification codes. Transportation should only be performed by trained personnel following ADR/IMDG regulations. Ensure vehicles are properly equipped and drivers hold valid dangerous goods licenses.

2-chloro-6-(trichloromethyl)pyridine is subject to REACH regulation in Europe and must comply with CLP classification and labeling requirements. It is not currently listed as a Substance of Very High Concern (SVHC). The compound requires safety data sheets and appropriate hazard communication due to its toxicity classification. Users must follow occupational exposure limits where established and implement risk management measures. Registration requirements under REACH apply for importers and manufacturers above tonnage thresholds.

2-chloro-6-(trichloromethyl)pyridine is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to industrial customers, research institutions, and chemical manufacturers across Europe. As a professional chemical distributor, OYSI ensures proper handling, packaging, and documentation compliance with European regulations. For pricing, availability, and technical specifications, contact OYSI directly through their sales channels. They can provide certificates of analysis and regulatory documentation required for your specific applications.