1,4,7,10-tetrakis-(4-methylphenyl)sulfonyl-1,4,7,10-tetrazacyclododecane

1,4,7,10-tetrakis-(4-methylphenyl)sulfonyl-1,4,7,10-tetrazacyclododecane is a complex organic compound with CAS number 52667-88-6. This chemical features a twelve-membered cyclic structure containing four nitrogen atoms (tetrazacyclododecane ring) with four methylphenylsulfonyl substituents. With a molecular formula of C36H44N4O8S4 and molecular weight of 789 g/mol, it belongs to the class of sulfonamide derivatives and is primarily used in specialized chemical applications requiring precise molecular recognition properties.

1,4,7,10-tetrakis-(4-methylphenyl)sulfonyl-1,4,7,10-tetrazacyclododecane is a solid compound at room temperature with a molecular weight of 789 g/mol. The compound contains multiple aromatic rings and sulfonyl groups, suggesting limited water solubility but potential solubility in organic solvents. Its cyclic tetrazacyclododecane structure with bulky substituents indicates a rigid, three-dimensional molecular geometry. The presence of sulfur and nitrogen atoms contributes to its chemical reactivity and coordination properties.

1,4,7,10-tetrakis-(4-methylphenyl)sulfonyl-1,4,7,10-tetrazacyclododecane serves as a specialized chemical intermediate in pharmaceutical research and advanced organic synthesis. Its tetrazacyclododecane core structure makes it valuable for developing metal chelating agents, molecular recognition systems, and specialized catalysts. The compound is commonly used in academic research, fine chemical manufacturing, and as a building block for more complex molecules requiring precise stereochemical control and coordination properties in specialized industrial applications.

1,4,7,10-tetrakis-(4-methylphenyl)sulfonyl-1,4,7,10-tetrazacyclododecane requires careful handling due to its skin sensitization potential (Skin Sens. 1). Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to minimize exposure. Avoid direct skin contact and inhalation. Wash hands thoroughly after handling and ensure proper training on the material safety data sheet before use.

1,4,7,10-tetrakis-(4-methylphenyl)sulfonyl-1,4,7,10-tetrazacyclododecane should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers tightly closed and properly labeled. Due to its aquatic toxicity classification, ensure storage areas have appropriate containment measures to prevent environmental release. Store away from incompatible materials and maintain ambient temperature conditions. Regular inspection of containers for damage or leakage is recommended to ensure continued safe storage.

Immediate action is required if contact occurs with 1,4,7,10-tetrakis-(4-methylphenyl)sulfonyl-1,4,7,10-tetrazacyclododecane due to its skin sensitization properties. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. If eye contact occurs, flush immediately with clean water for 15 minutes. In case of inhalation, move to fresh air. Seek medical attention if irritation persists or allergic reactions develop. Never induce vomiting if ingested.

1,4,7,10-tetrakis-(4-methylphenyl)sulfonyl-1,4,7,10-tetrazacyclododecane must be disposed of through authorized hazardous waste management facilities due to its aquatic toxicity classification. Never dispose of this material down drains, in regular waste, or release to the environment. Collect waste in appropriate, labeled containers and consult local environmental regulations for specific disposal requirements. Professional waste disposal companies specializing in chemical waste should handle the final disposal to ensure compliance with environmental protection standards.

1,4,7,10-tetrakis-(4-methylphenyl)sulfonyl-1,4,7,10-tetrazacyclododecane is classified as ADR Class 9 (miscellaneous dangerous goods), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation for shipping. Containers must meet UN specification requirements and display proper hazard labels. Transportation must comply with ADR/RID regulations for road and rail transport. Professional logistics providers experienced in chemical transportation should handle shipments to ensure regulatory compliance and safe delivery.

1,4,7,10-tetrakis-(4-methylphenyl)sulfonyl-1,4,7,10-tetrazacyclododecane is subject to standard chemical regulations but is not classified as a SVHC (Substance of Very High Concern). It falls under REACH registration requirements in Europe and CLP classification due to its hazard properties (skin sensitization and aquatic toxicity). Users must comply with occupational safety regulations, environmental protection laws, and proper waste management requirements. Regular monitoring of regulatory updates is recommended as classification may evolve.

1,4,7,10-tetrakis-(4-methylphenyl)sulfonyl-1,4,7,10-tetrazacyclododecane is available through OYSI, a specialized European distributor of high-quality chemical products. As an established supplier of fine chemicals and research materials, OYSI provides this specialized compound to pharmaceutical companies, research institutions, and chemical manufacturers across Europe. Contact OYSI directly for availability, technical specifications, and regulatory documentation. Their experienced team can provide guidance on handling, storage, and compliance requirements for your specific application needs.