1,1-bis(4-chlorophenyl)ethanol

C14H12Cl2O

CAS80-06-8
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
80-06-8
EC Number
201-246-3
UN Number
3077
Index Number
603-049-00-1
PubChem CID
6624

Physical-chemical properties

Molecular Formula
C14H12Cl2O
Molar Mass
267.10 g/mol
IUPAC Name
1,1-bis(4-chlorophenyl)ethanol

Chemical Identifiers

InChI
InChI=1S/C14H12Cl2O/c1-14(17,10-2-6-12(15)7-3-10)11-4-8-13(16)9-5-11/h2-9,17H,1H3
InChI Key
URYAFVKLYSEINW-UHFFFAOYSA-N

Overview

1,1-bis(4-chlorophenyl)ethanol (CAS 80-06-8) is an organochlorine alcohol compound featuring two chlorinated phenyl rings attached to a central ethanol group. This specialized chemical intermediate represents an important member of the chlorinated aromatic alcohol family, distinguished by its symmetrical molecular structure containing two para-chlorophenyl substituents. With the molecular formula C14H12Cl2O and a molecular weight of 267.1 g/mol, this compound exhibits unique physicochemical properties that make it valuable for various industrial applications requiring specific reactivity patterns. From a safety perspective, 1,1-bis(4-chlorophenyl)ethanol is classified under the GHS system with acute toxicity category 4 and chronic aquatic toxicity category 2, requiring appropriate handling protocols and environmental considerations. The compound carries a "Warning" signal word and is associated with GHS07 and GHS09 pictograms, indicating both health hazards and environmental concerns. Transportation falls under ADR class 9, designating it as a miscellaneous dangerous substance. The compound finds primary applications in pharmaceutical intermediate synthesis, where its chlorinated aromatic structure provides specific reactivity for complex molecule construction. It also serves as a precursor in specialty polymer chemistry and as a building block for advanced materials requiring chlorinated aromatic functionalities. Unlike simpler compounds such as benzyl(tributyl)azanium;4-hydroxynaphthalene-1-sulfonate, this molecule offers enhanced thermal stability and specific electronic properties due to its dichlorophenyl substitution pattern. OYSI maintains reliable supply chains for 1,1-bis(4-chlorophenyl)ethanol to support European industrial customers requiring consistent quality and regulatory compliance for their specialized chemical processes.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameChlorfenethol (ISO)
Marine PollutantNo

Frequently Asked Questions

What is 1,1-bis(4-chlorophenyl)ethanol?

1,1-bis(4-chlorophenyl)ethanol is an organochlorine compound with the molecular formula C14H12Cl2O and CAS number 80-06-8. This chemical features two chlorinated phenyl rings attached to a central carbon bearing a hydroxyl group and a methyl group. With a molecular weight of 267.1 g/mol, it appears as a white to off-white crystalline solid at room temperature. The compound is classified as moderately toxic and poses environmental concerns for aquatic ecosystems.

What are the physicochemical properties of 1,1-bis(4-chlorophenyl)ethanol?

1,1-bis(4-chlorophenyl)ethanol is a white to off-white crystalline solid at room temperature with limited water solubility due to its hydrophobic chlorinated aromatic structure. The compound has a molecular weight of 267.1 g/mol and contains two chlorine atoms contributing to its stability and persistence. It exhibits moderate volatility and is typically odorless or has a faint aromatic odor. The presence of the hydroxyl group provides some polar character while the chlorinated phenyl rings dominate its overall hydrophobic nature.

What is 1,1-bis(4-chlorophenyl)ethanol used for?

1,1-bis(4-chlorophenyl)ethanol is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing processes. It serves as a precursor for various chemical transformations and can be employed in the production of specialty chemicals. The compound may also find applications in research and development activities within chemical and pharmaceutical industries. Its chlorinated aromatic structure makes it valuable for creating more complex molecular architectures through further chemical modifications and coupling reactions.

How to handle 1,1-bis(4-chlorophenyl)ethanol safely?

1,1-bis(4-chlorophenyl)ethanol requires careful handling due to its Acute Tox. 4 classification and environmental hazards. Personnel must wear appropriate personal protective equipment including nitrile gloves, safety goggles, and laboratory coats. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and wash hands thoroughly after handling. Ensure emergency eyewash and shower facilities are accessible, and train personnel on proper handling procedures before use.

How to store 1,1-bis(4-chlorophenyl)ethanol correctly?

1,1-bis(4-chlorophenyl)ethanol should be stored in a cool, dry, well-ventilated area away from incompatible materials and ignition sources. Keep containers tightly sealed and properly labeled in secondary containment to prevent environmental release. Storage areas should be equipped with appropriate spill response materials and maintain temperatures below 25°C when possible. Separate from strong oxidizing agents, acids, and bases. Implement inventory rotation using first-in, first-out principles and conduct regular container inspections for damage or leakage.

What to do in case of contact with 1,1-bis(4-chlorophenyl)ethanol?

Immediate action is required upon contact with 1,1-bis(4-chlorophenyl)ethanol due to its toxicity classification. For skin contact, remove contaminated clothing and wash affected area with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes while keeping eyelids open. If ingested, do not induce vomiting and seek immediate medical attention. For inhalation exposure, move to fresh air immediately. Always seek professional medical advice and provide safety data sheet information to healthcare providers.

How to dispose of 1,1-bis(4-chlorophenyl)ethanol appropriately?

1,1-bis(4-chlorophenyl)ethanol must be disposed of through licensed hazardous waste disposal facilities due to its toxicity and environmental persistence. The compound cannot be disposed of in regular waste streams or sewage systems due to its Aquatic Chronic 2 classification. Contact certified waste management companies specializing in hazardous chemical disposal. Ensure proper waste classification, packaging, and documentation according to local environmental regulations. Small laboratory quantities may require special collection procedures, while larger industrial amounts need comprehensive waste manifests and tracking.

How to transport 1,1-bis(4-chlorophenyl)ethanol?

1,1-bis(4-chlorophenyl)ethanol is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation during shipment. Containers must meet UN specification requirements and display proper hazard labels and orientation arrows. Transport vehicles need appropriate placarding, and drivers require hazardous materials training certification. Shipping documentation must include proper shipping names, hazard classes, and emergency response information. Ensure compliance with international transport regulations for safe delivery.

Is 1,1-bis(4-chlorophenyl)ethanol subject to specific regulations?

1,1-bis(4-chlorophenyl)ethanol is subject to REACH registration requirements in Europe and must comply with CLP regulation for classification and labeling. The compound is not currently listed as a Substance of Very High Concern (SVHC), but users must still follow standard chemical safety protocols. Industrial users may need to implement risk management measures and maintain safety data sheets. Environmental discharge limits may apply due to its aquatic toxicity classification. Occupational exposure limits and workplace safety measures must comply with national health and safety regulations.

Where to buy 1,1-bis(4-chlorophenyl)ethanol in Europe?

1,1-bis(4-chlorophenyl)ethanol is available through OYSI, a specialized European distributor of technical chemicals serving industrial and research customers across the continent. OYSI provides this compound with full regulatory compliance documentation, including safety data sheets and certificates of analysis. As an established chemical distributor, OYSI ensures proper packaging, handling, and delivery logistics for hazardous materials. Contact OYSI directly for current availability, technical specifications, and pricing information to meet your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.