1-octylpyrrolidin-2-one

1-octylpyrrolidin-2-one is an organic chemical compound with the molecular formula C12H23NO and CAS number 2687-94-7. It belongs to the pyrrolidinone family, featuring a five-membered lactam ring with an eight-carbon alkyl chain attached. With a molecular weight of 197.32 g/mol, this compound is classified as a skin corrosive substance and poses environmental hazards to aquatic life.

1-octylpyrrolidin-2-one is a liquid organic compound at room temperature with moderate viscosity due to its long alkyl chain. The substance exhibits typical properties of N-alkylated lactams, including good solubility in organic solvents and limited water solubility. Its amphiphilic nature, combining the polar lactam group with the hydrophobic octyl chain, gives it surfactant-like properties and makes it useful in various industrial applications.

1-octylpyrrolidin-2-one is primarily used as a solvent and penetration enhancer in pharmaceutical and cosmetic formulations. Its excellent skin penetration properties make it valuable in transdermal drug delivery systems and topical preparations. The compound also serves as a chemical intermediate in organic synthesis and finds applications in specialty chemical formulations where its unique solvent properties and skin compatibility are required.

1-octylpyrrolidin-2-one must be handled with extreme caution due to its skin corrosive properties (Skin Corr. 1B). Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods. Avoid direct contact with skin, eyes, and clothing. Emergency shower and eyewash stations should be readily accessible when handling this corrosive substance.

1-octylpyrrolidin-2-one should be stored in tightly sealed, corrosion-resistant containers in a cool, dry, and well-ventilated area away from incompatible materials. Keep containers away from heat sources, direct sunlight, and ignition sources. Storage areas should be equipped with appropriate spill containment measures due to the substance's corrosive nature and potential environmental impact. Regular container inspections are recommended to prevent leaks.

Immediate action is critical due to the corrosive nature of 1-octylpyrrolidin-2-one. In case of skin contact, immediately remove contaminated clothing and rinse affected area with copious amounts of water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. Seek immediate medical attention in all cases of contact. Do not neutralize with chemicals.

1-octylpyrrolidin-2-one must be disposed of as hazardous waste according to local and national regulations. The substance cannot be disposed of in regular waste streams due to its corrosive properties and environmental classification (Aquatic Chronic 2). Contact licensed hazardous waste disposal companies for proper treatment and disposal. Ensure proper labeling and documentation throughout the disposal process to maintain regulatory compliance.

1-octylpyrrolidin-2-one is classified under ADR as Class 8 (corrosive substances), Packing Group II, indicating moderate danger during transport. The substance requires appropriate corrosive-resistant packaging and proper hazard labeling during shipment. Transportation must comply with ADR regulations for corrosive materials, including specific packaging instructions, vehicle requirements, and driver training. Only authorized carriers experienced in handling corrosive chemicals should transport this substance.

1-octylpyrrolidin-2-one is subject to standard chemical regulations including REACH registration and CLP classification requirements in Europe. The substance is classified as Skin Corr. 1B and Aquatic Chronic 2, requiring appropriate hazard communication and safety measures. While not currently listed as a Substance of Very High Concern (SVHC), users must comply with occupational safety regulations and environmental protection measures when handling this corrosive chemical.

1-octylpyrrolidin-2-one is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this corrosive substance to qualified industrial and research customers with proper handling capabilities. Due to the hazardous nature of this chemical, purchases typically require verification of appropriate safety measures and handling expertise. Contact OYSI directly for availability, technical specifications, and regulatory documentation for your specific application requirements.