1-nitro-4-phenylbenzene

C12H9NO2

CAS92-93-3
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
92-93-3
EC Number
202-204-7
UN Number
3077
Index Number
609-039-00-3
PubChem CID
7114

Physical-chemical properties

Molecular Formula
C12H9NO2
Molar Mass
199.20 g/mol
IUPAC Name
1-nitro-4-phenylbenzene

Chemical Identifiers

InChI
InChI=1S/C12H9NO2/c14-13(15)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H
InChI Key
BAJQRLZAPXASRD-UHFFFAOYSA-N

Overview

1-nitro-4-phenylbenzene (CAS 92-93-3) is a nitroaromatic compound featuring a biphenyl structure with a nitro functional group providing distinctive chemical reactivity. This organic compound, also known by its IUPAC designation 1-nitro-4-phenylbenzene, represents an important member of the nitroaromatic chemical family with the molecular formula C12H9NO2 and a molecular weight of 199.2 g/mol. The substance exhibits a characteristic biphenyl backbone where a nitro group is positioned para to the phenyl substituent, creating specific electronic properties that make it valuable for various industrial applications. From a safety perspective, 1-nitro-4-phenylbenzene requires careful handling due to its classification as a Category 1B carcinogen and Aquatic Chronic 2 substance, necessitating appropriate protective measures and environmental controls. The compound carries GHS08 and GHS09 pictograms with a "Danger" signal word, reflecting its potential health and environmental hazards. Transportation falls under ADR Class 9, indicating it requires special consideration during shipping and storage operations. The compound finds primary applications in the chemical industry as an intermediate for dye synthesis, pharmaceutical manufacturing, and specialty chemical production. Its structural similarity to compounds like 2-nitronaphthalene makes it particularly useful in aromatic substitution reactions and as a building block for more complex molecular structures. Additionally, it serves as a precursor in the synthesis of various organic compounds where the nitro group can be selectively modified or reduced. Industrial users also employ 1-nitro-4-phenylbenzene in research and development applications, particularly in materials science and organic synthesis protocols. OYSI maintains reliable supply chains for this technical grade chemical, supporting European customers with consistent quality and regulatory compliance documentation.

Safety & Classification

Danger
Classification:

Carc. 1B; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name4-Nitrobiphenyl
Marine PollutantNo

Frequently Asked Questions

What is 1-nitro-4-phenylbenzene?

1-nitro-4-phenylbenzene is an aromatic nitro compound with the molecular formula C12H9NO2 and CAS number 92-93-3. This chemical consists of a biphenyl structure with a nitro group (-NO2) attached to one of the benzene rings. With a molecular weight of 199.2 g/mol, it belongs to the class of nitroaromatic compounds and is classified as a Category 1B carcinogen under GHS classification.

What are the physicochemical properties of 1-nitro-4-phenylbenzene?

1-nitro-4-phenylbenzene is typically a crystalline solid at room temperature with a characteristic aromatic odor. As an aromatic nitro compound, it exhibits limited water solubility but dissolves well in organic solvents such as alcohols, ethers, and aromatic hydrocarbons. The compound's biphenyl structure contributes to its stability and relatively high melting point, making it suitable for various industrial applications requiring thermal stability.

What is 1-nitro-4-phenylbenzene used for?

1-nitro-4-phenylbenzene serves primarily as an intermediate in organic synthesis and pharmaceutical manufacturing. It is commonly used in the production of dyes, pigments, and other aromatic compounds through reduction or substitution reactions. The compound also finds applications in research laboratories for synthetic chemistry studies and as a precursor for the manufacture of specialized chemicals in the fine chemical industry.

How to handle 1-nitro-4-phenylbenzene safely?

1-nitro-4-phenylbenzene requires strict safety measures due to its carcinogenic properties (Carc. 1B classification). Essential personal protective equipment includes nitrile gloves, safety goggles, and respiratory protection in well-ventilated areas or fume hoods. Avoid skin contact, inhalation, and ingestion. Work in designated areas with proper containment measures, and ensure all personnel are trained in handling carcinogenic substances according to occupational safety regulations.

How to store 1-nitro-4-phenylbenzene correctly?

1-nitro-4-phenylbenzene should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep away from strong reducing agents, alkali metals, and oxidizing substances that could cause dangerous reactions. Storage areas must be secured and restricted to authorized personnel only, with appropriate warning signs indicating the carcinogenic hazard and environmental risks.

What to do in case of contact with 1-nitro-4-phenylbenzene?

1-nitro-4-phenylbenzene exposure requires immediate action due to its carcinogenic nature. For skin contact, immediately remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with clean water for 15 minutes. Seek immediate medical attention in all cases of exposure and inform medical personnel about the carcinogenic classification of the substance.

How to dispose of 1-nitro-4-phenylbenzene appropriately?

1-nitro-4-phenylbenzene disposal must comply with hazardous waste regulations due to its carcinogenic classification and environmental impact. The substance cannot be disposed of in regular waste streams and requires treatment by licensed hazardous waste disposal companies. Incineration at high temperatures in specialized facilities is typically required. All disposal activities must be documented and follow local, national, and EU waste management regulations for carcinogenic substances.

How to transport 1-nitro-4-phenylbenzene?

1-nitro-4-phenylbenzene is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. Proper packaging includes approved containers with appropriate hazard labels and documentation. Transport vehicles must comply with ADR regulations for Class 9 substances, including proper segregation from incompatible materials and emergency response information. Drivers require appropriate training for transporting hazardous materials under ADR regulations.

Is 1-nitro-4-phenylbenzene subject to specific regulations?

1-nitro-4-phenylbenzene is subject to extensive regulatory oversight under REACH and CLP regulations due to its carcinogenic classification (Carc. 1B). Users must comply with authorization requirements, exposure controls, and risk management measures. The substance requires safety data sheets, proper labeling with GHS08 and GHS09 pictograms, and adherence to occupational exposure limits. Environmental release monitoring may also be required under certain jurisdictions.

Where to buy 1-nitro-4-phenylbenzene in Europe?

1-nitro-4-phenylbenzene is available through OYSI, a specialized European distributor of industrial chemicals with expertise in hazardous substance handling. As a professional chemical supplier, OYSI ensures compliance with REACH registration requirements, provides complete documentation including safety data sheets, and offers technical support for safe handling procedures. Contact OYSI directly for availability, specifications, and regulatory compliance documentation for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.