1-nitro-4-phenylbenzene

C12H9NO2

CAS92-93-3
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
92-93-3
EC Number
202-204-7
UN Number
3077
Index Number
609-039-00-3
PubChem CID
7114

Physical-chemical properties

Molecular Formula
C12H9NO2
Molar Mass
199.20 g/mol
IUPAC Name
1-nitro-4-phenylbenzene

Chemical Identifiers

InChI
InChI=1S/C12H9NO2/c14-13(15)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H
InChI Key
BAJQRLZAPXASRD-UHFFFAOYSA-N

Overview

1-nitro-4-phenylbenzene (CAS 92-93-3) is an aromatic nitro compound characterized by its biphenyl structure with a nitro functional group and significant industrial applications. This chemical compound, also known by its IUPAC name 1-nitro-4-phenylbenzene, represents an important member of the nitroaromatic family with the molecular formula C12H9NO2 and a molecular weight of 199.2 g/mol. The substance features a distinctive structure consisting of two benzene rings connected directly, with one ring bearing a nitro group in the para position relative to the biphenyl linkage. This structural arrangement provides unique chemical properties that make it valuable in various industrial processes. From a safety perspective, 1-nitro-4-phenylbenzene requires careful handling due to its classification as a Category 1B carcinogen and its potential for chronic aquatic toxicity. The compound displays the GHS08 health hazard and GHS09 environmental hazard pictograms, with "Danger" as the signal word. Transportation falls under ADR Class 9 (miscellaneous dangerous substances), reflecting its regulatory status and the need for appropriate safety protocols during storage, handling, and transport. The compound shares structural similarities with other nitroaromatic substances such as 2-nitronaphthalene, which also contains aromatic ring systems with nitro functionality. These related compounds often find applications in similar industrial sectors, particularly in the synthesis of specialized organic intermediates. Primary industrial applications include its use as an intermediate in the production of dyes, pharmaceuticals, and specialty chemicals. The compound also serves as a precursor in the manufacture of various aromatic amines through reduction processes, and finds application in research and development of advanced materials. OYSI provides 1-nitro-4-phenylbenzene to European industrial customers with comprehensive technical support and regulatory compliance documentation.

Safety & Classification

Danger
Classification:

Carc. 1B; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name4-Nitrobiphenyl
Marine PollutantNo

Frequently Asked Questions

What is 1-nitro-4-phenylbenzene?

1-nitro-4-phenylbenzene is an organic chemical compound with the molecular formula C12H9NO2 and CAS number 92-93-3. This aromatic nitro compound consists of two benzene rings connected by a single bond, with one ring bearing a nitro group (-NO2). It has a molecular weight of 199.2 g/mol and is classified as a Category 1B carcinogen, making it a substance of significant health concern requiring careful handling in industrial and research applications.

What are the physicochemical properties of 1-nitro-4-phenylbenzene?

1-nitro-4-phenylbenzene is typically a crystalline solid at room temperature with characteristic aromatic properties. As an aromatic nitro compound, it exhibits limited water solubility but dissolves well in organic solvents such as alcohols, ethers, and aromatic hydrocarbons. The compound's biphenyl structure with the electron-withdrawing nitro group influences its chemical reactivity and physical properties, making it stable under normal conditions but reactive under specific chemical environments.

What is 1-nitro-4-phenylbenzene used for?

1-nitro-4-phenylbenzene serves primarily as an intermediate in organic synthesis and chemical manufacturing processes. It is commonly used in the production of dyes, pigments, and pharmaceutical intermediates. The compound also finds applications in research laboratories for synthetic organic chemistry reactions, particularly in the preparation of substituted biphenyl derivatives. Due to its carcinogenic classification, its use is restricted to professional and industrial settings with appropriate safety controls.

How to handle 1-nitro-4-phenylbenzene safely?

1-nitro-4-phenylbenzene requires strict safety protocols due to its Category 1B carcinogenic classification. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection when handling powders or in poorly ventilated areas. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Direct skin contact must be avoided at all times, and proper hygiene practices including thorough handwashing after handling are mandatory.

How to store 1-nitro-4-phenylbenzene correctly?

1-nitro-4-phenylbenzene should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Storage areas must be secure and restricted to authorized personnel due to the compound's carcinogenic properties. The chemical should be kept separate from strong oxidizing agents, reducing agents, and incompatible materials. Proper labeling with hazard warnings and safety data sheets must be readily accessible in storage areas.

What to do in case of contact with 1-nitro-4-phenylbenzene?

Immediate action is required for any contact with 1-nitro-4-phenylbenzene due to its carcinogenic nature. For skin contact, remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention promptly for any exposure, informing healthcare providers of the substance's carcinogenic classification.

How to dispose of 1-nitro-4-phenylbenzene properly?

1-nitro-4-phenylbenzene must be disposed of as hazardous waste through licensed waste management companies in accordance with local and national regulations. The compound cannot be disposed of in regular waste streams due to its carcinogenic properties and potential environmental impact. Waste containers should be properly labeled and stored securely until collection. Incineration at high temperatures in specialized facilities is typically the preferred disposal method, following all applicable environmental and safety regulations.

How to transport 1-nitro-4-phenylbenzene?

1-nitro-4-phenylbenzene is classified under ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transportation purposes. It must be packaged in approved containers with proper hazard labels and documentation including transport documents and safety data sheets. Vehicles used for transport should be equipped with appropriate emergency equipment and drivers must be trained in hazardous materials handling. All transport must comply with ADR regulations and national dangerous goods transport requirements.

Is 1-nitro-4-phenylbenzene subject to specific regulations?

1-nitro-4-phenylbenzene is subject to extensive regulatory oversight under European REACH and CLP regulations due to its Category 1B carcinogenic classification. The compound requires registration for commercial use and is subject to strict occupational exposure limits and workplace safety requirements. Users must implement risk management measures and maintain detailed records of use and exposure. Additional national regulations may apply depending on the country of use, particularly regarding occupational health and environmental protection.

Where to buy 1-nitro-4-phenylbenzene in Europe?

1-nitro-4-phenylbenzene is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous materials handling. As a professional chemical supplier, OYSI ensures proper packaging, labeling, and documentation compliance with European regulations including REACH and CLP requirements. Due to the substance's carcinogenic classification, purchases are restricted to qualified professional and industrial users who can demonstrate appropriate safety measures and legitimate use requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.