1-(4-aminophenyl)-N-methylmethanesulfonamide;hydrochloride

1-(4-aminophenyl)-N-methylmethanesulfonamide;hydrochloride is an organic chemical compound with the molecular formula C8H13ClN2O2S and CAS number 88918-84-7. This substance has a molecular weight of 236.72 g/mol and contains both aminophenyl and sulfonamide functional groups. It is classified as a hazardous chemical due to its potential for causing serious eye damage and skin sensitization, requiring careful handling in industrial applications.

1-(4-aminophenyl)-N-methylmethanesulfonamide;hydrochloride is a solid compound with a molecular weight of 236.72 g/mol and molecular formula C8H13ClN2O2S. As a hydrochloride salt, it typically exhibits good water solubility. The compound contains aromatic amine and sulfonamide functional groups, which influence its chemical reactivity and stability. Specific physical properties such as melting point, color, and odor may vary depending on purity and crystalline form.

1-(4-aminophenyl)-N-methylmethanesulfonamide;hydrochloride is primarily used as a chemical intermediate in pharmaceutical and fine chemical synthesis. The compound's aminophenyl and sulfonamide functional groups make it valuable for developing pharmaceutical compounds, particularly those requiring sulfonamide derivatives. It may also serve as a building block in research and development applications for medicinal chemistry, where its structural features are incorporated into larger molecular frameworks for drug discovery purposes.

1-(4-aminophenyl)-N-methylmethanesulfonamide;hydrochloride requires strict safety precautions due to its classification as Eye Dam. 1 and Skin Sens. 1. Essential protective equipment includes chemical-resistant gloves, safety goggles or face shield, and protective clothing. Work in well-ventilated areas or under fume hoods to prevent inhalation. Avoid direct contact with skin and eyes, and ensure emergency eyewash stations are accessible. Handle with appropriate tools and follow established chemical handling protocols.

1-(4-aminophenyl)-N-methylmethanesulfonamide;hydrochloride should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Keep away from heat sources, direct sunlight, and moisture to prevent degradation. Store in designated chemical storage areas with appropriate labeling and secondary containment. Due to its eye damage and skin sensitization properties, ensure storage areas are accessible only to trained personnel and equipped with appropriate safety equipment.

Immediate action is critical due to the substance's Eye Dam. 1 classification. For eye contact, immediately flush with large amounts of water for at least 15 minutes and seek immediate medical attention. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention. Always consult the safety data sheet for specific first aid measures.

1-(4-aminophenyl)-N-methylmethanesulfonamide;hydrochloride must be disposed of as hazardous chemical waste according to local and national regulations. Do not dispose of in regular trash or pour down drains due to its Aquatic Chronic 2 classification. Contact licensed hazardous waste disposal companies for proper collection and treatment. Contaminated materials, containers, and protective equipment should also be treated as hazardous waste. Maintain documentation of all disposal activities for regulatory compliance.

1-(4-aminophenyl)-N-methylmethanesulfonamide;hydrochloride is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. This classification requires specific packaging, labeling, and documentation according to international dangerous goods regulations. Packages must display appropriate hazard labels and UN identification numbers. Transport vehicles must carry proper documentation and emergency response information. Only trained personnel should handle transportation, and drivers require ADR certification for dangerous goods transport.

1-(4-aminophenyl)-N-methylmethanesulfonamide;hydrochloride is subject to REACH regulation in Europe and CLP classification requirements. The substance carries GHS hazard pictograms GHS05, GHS07, and GHS09 with 'Danger' signal word. It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational exposure limits, waste disposal regulations, and transport requirements. Registration, evaluation, and authorization requirements under REACH may apply depending on quantities handled and intended use.

1-(4-aminophenyl)-N-methylmethanesulfonamide;hydrochloride is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to pharmaceutical, research, and industrial customers across Europe with proper regulatory documentation and safety data sheets. As a hazardous chemical requiring specialized handling and transport, procurement should only be through established chemical distributors who can ensure proper packaging, labeling, and regulatory compliance for safe delivery.