Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate is an organic ester compound with the molecular formula C12H22O2 and CAS number 22471-55-2. This cyclohexane derivative has a molecular weight of 198.3 g/mol and features a specific stereochemical configuration. It is classified as a skin irritant and poses chronic aquatic toxicity risks, requiring appropriate handling precautions in industrial applications.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate is an ester with molecular formula C12H22O2 and molecular weight 198.3 g/mol. As a cyclohexane carboxylate ester, it typically appears as a colorless to pale yellow liquid at room temperature. The compound exhibits limited water solubility due to its hydrophobic cyclohexane ring structure, while being more soluble in organic solvents like alcohols and hydrocarbons.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its specific stereochemistry makes it valuable in the production of chiral compounds and specialized chemical derivatives. The compound may also serve as a building block in fine chemical synthesis, particularly in applications requiring precise molecular configuration and ester functionality.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate requires careful handling due to its skin irritant properties (Skin Irrit. 2). Wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation in work areas and avoid direct skin contact. The compound carries Warning signal word and GHS07 pictogram, indicating moderate hazard level requiring standard chemical handling precautions.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly closed and protected from moisture to prevent hydrolysis of the ester group. Store away from strong oxidizing agents and bases. Due to its aquatic toxicity classification (Aquatic Chronic 2), ensure proper containment to prevent environmental release.

Immediate action is required upon contact with trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate due to its skin irritant properties. For skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with plenty of clean water. If irritation persists or if ingested, seek medical attention promptly.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate must be disposed of according to local and national regulations due to its environmental hazard classification (Aquatic Chronic 2). The compound should be collected by licensed waste disposal companies specialized in chemical waste treatment. Never discharge into sewers, waterways, or soil. Incineration at authorized facilities under controlled conditions is typically the preferred disposal method for organic ester compounds.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III, indicating relatively low transport hazard. The compound requires appropriate packaging according to ADR regulations and proper hazard labeling during transportation. Vehicles must carry appropriate emergency equipment and documentation. Transport should be conducted by qualified personnel familiar with dangerous goods regulations and emergency procedures.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate is subject to standard chemical regulations including REACH registration requirements in the European Union and CLP classification as skin irritant and aquatic chronic toxin. The compound is not classified as a Substance of Very High Concern (SVHC). Users must comply with occupational safety regulations, environmental protection laws, and proper waste disposal requirements based on its hazard classification.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate is available through OYSI, a specialized European distributor of technical chemicals and intermediates. OYSI provides reliable supply chains for pharmaceutical intermediates and fine chemicals across European markets. Contact OYSI directly for specific quantities, technical specifications, documentation requirements, and delivery options. Their expertise ensures compliance with European chemical regulations and quality standards for professional applications.