Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate is an organic chemical compound with the molecular formula C12H22O2 and molecular weight of 198.3 g/mol. It belongs to the class of cyclohexane carboxylic acid esters with specific stereochemistry indicated by the (1R,6S) configuration. The compound features a six-membered cyclohexane ring with three methyl substituents and an ethyl ester functional group, making it a complex ester derivative used in various chemical applications.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate is a liquid organic compound at room temperature with a molecular weight of 198.3 g/mol. As an ester, it typically exhibits low water solubility but good solubility in organic solvents such as alcohols, ethers, and hydrocarbons. The compound likely has a characteristic fruity or pleasant ester odor and appears as a clear to pale yellow liquid under normal conditions.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate is primarily used as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. Its specific stereochemistry makes it valuable for producing enantiomerically pure compounds in the pharmaceutical industry. The compound may also serve as a building block for specialty chemicals, fragrance components, or as a reagent in research and development applications where precise molecular structure is required.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate requires careful handling due to its skin irritant properties (Skin Irrit. 2). Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation exposure. Prevent direct skin and eye contact, and wash hands thoroughly after handling. The compound carries a Warning signal word and GHS07 pictogram indicating health hazards.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers tightly closed and store in compatible materials resistant to organic solvents. Due to its aquatic chronic toxicity (Aquatic Chronic 2), ensure proper secondary containment to prevent environmental release. Store away from strong oxidizing agents and bases that could cause hydrolysis of the ester bond.

In case of skin contact with trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate, immediately remove contaminated clothing and wash the affected area with soap and plenty of water for at least 15 minutes. For eye contact, rinse immediately with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. If swallowed, rinse mouth with water and seek medical advice. Do not induce vomiting and consult a physician if symptoms persist.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate must be disposed of according to local and national hazardous waste regulations due to its environmental impact (Aquatic Chronic 2). Contact licensed waste disposal companies for proper treatment and disposal. Do not discharge into drains, waterways, or soil. Small quantities may be incinerated in approved facilities with appropriate emission controls. Always check with local environmental authorities for specific disposal requirements and approved disposal facilities in your region.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transport purposes. Use appropriate UN-specification packaging and ensure proper labeling with GHS07 and GHS09 pictograms. Transport documents must include the correct shipping name and UN number. Ensure vehicles are properly equipped and drivers have appropriate training for Class 9 materials. Follow all applicable domestic and international transport regulations for miscellaneous dangerous goods.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate is subject to standard chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The compound is not identified as a Substance of Very High Concern (SVHC). It must be classified and labeled according to GHS/CLP regulations with Warning signal word and appropriate pictograms (GHS07, GHS09). Suppliers must provide safety data sheets and ensure proper registration under REACH for quantities above registration thresholds.

Trans-ethyl (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylate is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this compound with full regulatory compliance, proper documentation, and technical support throughout Europe. Contact OYSI directly for availability, specifications, and pricing information. As a professional chemical distributor, OYSI ensures proper packaging, labeling, and documentation to meet all regulatory requirements for this specialized organic compound.