Phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate

C15H7Cl2F3N2O2

phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate

CAS14255-88-0
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
14255-88-0
EC Number
238-134-9
UN Number
2757
Index Number
613-015-00-8
PubChem CID
26597

Physical-chemical properties

Molecular Formula
C15H7Cl2F3N2O2
Molar Mass
375.10 g/mol
IUPAC Name
phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate

Chemical Identifiers

InChI
InChI=1S/C15H7Cl2F3N2O2/c16-9-6-11-12(7-10(9)17)22(13(21-11)15(18,19)20)14(23)24-8-4-2-1-3-5-8/h1-7H
InChI Key
ISVQSVPUDBVFFU-UHFFFAOYSA-N

Overview

Phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate (CAS 14255-88-0) is a halogenated benzimidazole derivative with notable toxicological properties and environmental persistence. This specialized organic compound belongs to the benzimidazole family and features a complex molecular structure incorporating multiple halogen substituents, including chlorine and fluorine atoms. With a molecular formula of C15H7Cl2F3N2O2 and molecular weight of 375.1 g/mol, this substance exhibits unique chemical characteristics due to its trifluoromethyl group and dichlorosubstitution pattern on the benzimidazole core. The compound presents significant safety considerations, classified under Acute Toxicity Category 4 and carrying aquatic toxicity classifications (Aquatic Acute 1, Aquatic Chronic 1). These classifications reflect its potential environmental impact and require careful handling protocols. The substance displays GHS07 and GHS09 pictograms with a "Warning" signal word, indicating both health hazards and environmental concerns. For transportation purposes, it falls under ADR Class 6.1, designating it as a toxic substance requiring appropriate shipping precautions. In industrial applications, phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate serves primarily as an intermediate in pharmaceutical synthesis and agrochemical production. Its structural complexity makes it valuable in developing specialized compounds where halogenated aromatic systems are required. The compound shares certain application areas with related substances such as ethyl 2-dimethoxyphosphinothioylsulfanyl-2-phenylacetate, though each offers distinct reactivity profiles for specific synthetic pathways. OYSI maintains availability of this technical-grade compound for qualified industrial customers, supporting European chemical manufacturing and research applications with appropriate documentation and regulatory compliance.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; Acute Tox. 4 *; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2757
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameFenazaflor (ISO)
Marine PollutantNo

Frequently Asked Questions

What is phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate?

Phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate is a synthetic organic compound with the molecular formula C15H7Cl2F3N2O2 and CAS number 14255-88-0. This benzimidazole derivative has a molecular weight of 375.1 g/mol and contains chlorine and trifluoromethyl functional groups. It is classified as a hazardous substance with acute toxicity and environmental hazard properties, requiring careful handling and storage procedures.

What are the physicochemical properties of phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate?

Phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate is a solid compound at room temperature with a molecular weight of 375.1 g/mol. The presence of chlorine atoms and trifluoromethyl groups typically confers low water solubility and high chemical stability. As a halogenated aromatic compound, it likely appears as a white to off-white crystalline solid with minimal odor. Specific physical properties should be confirmed through technical data sheets.

What is phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate used for?

Phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate is primarily used as an intermediate in pharmaceutical and agrochemical synthesis. Its benzimidazole structure makes it valuable for developing fungicides, pharmaceuticals, and other bioactive compounds. The compound serves as a building block in chemical research and industrial applications where halogenated benzimidazole derivatives are required. Professional use is typically limited to controlled industrial and research environments due to its hazard classification.

How to handle phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate safely?

Phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate requires careful handling due to its Acute Tox. 4 classification. Wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume extraction systems. Avoid skin contact, inhalation, and ingestion. Use only trained personnel for handling operations. Keep containers tightly closed and handle according to good industrial hygiene practices to minimize exposure risks.

How to store phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate correctly?

Phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly sealed and protected from moisture and direct sunlight. Store separately from food, beverages, and animal feeds due to its acute toxicity classification. Maintain storage areas with appropriate temperature control and ensure adequate ventilation. Follow local regulations for storing hazardous chemicals and maintain proper inventory records.

What to do in case of contact with phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate?

Immediate action is required following contact with phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with plenty of clean water for at least 15 minutes. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult a physician and provide the safety data sheet for proper medical treatment.

How to dispose of phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate appropriately?

Phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate must be disposed of as hazardous waste through authorized waste management companies. The compound cannot be disposed of in regular waste streams due to its acute toxicity and environmental hazard classification. Collect waste in appropriate, labeled containers and arrange disposal through licensed hazardous waste contractors. Follow local and European waste regulations including proper waste coding and documentation. Never discharge into drains, soil, or water bodies.

How to transport phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate?

Phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate is classified under ADR as Class 6.1 (toxic substances), Packing Group III. Transport requires appropriate UN-specification packaging and proper shipping documentation. Use approved containers with correct labeling including GHS07 and GHS09 pictograms. Ensure drivers have appropriate ADR training for Class 6.1 materials. Follow dangerous goods regulations for road transport including proper vehicle marking and emergency procedures during transportation.

Is phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate subject to specific regulations?

Phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate is subject to European REACH and CLP regulations due to its hazardous classification. The compound is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with safety data sheet requirements, proper classification and labeling under CLP, and workplace exposure regulations. Registration obligations under REACH may apply depending on import/manufacturing volumes. Always verify current regulatory status and compliance requirements with local authorities.

Where to buy phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate in Europe?

Phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate is available through OYSI, a leading European distributor of specialty chemicals. OYSI provides this compound to qualified industrial and research customers across Europe with proper documentation and regulatory compliance. The compound is typically available for professional use only due to its hazardous classification. Contact OYSI directly for availability, technical specifications, and pricing information. Ensure your organization has appropriate handling capabilities before ordering.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.