Methyl 2-chloro-3-(4-chlorophenyl)propanoate
C10H10Cl2O2
methyl 2-chloro-3-(4-chlorophenyl)propanoate
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Identification
- CAS Number
- 14437-17-3
- EC Number
- 238-413-5
- UN Number
- 2996
- Index Number
- 607-075-00-4
- PubChem CID
- 26693
Physical-chemical properties
- Molecular Formula
- C10H10Cl2O2
- Molar Mass
- 233.09 g/mol
- IUPAC Name
- methyl 2-chloro-3-(4-chlorophenyl)propanoate
Chemical Identifiers
- InChI
- InChI=1S/C10H10Cl2O2/c1-14-10(13)9(12)6-7-2-4-8(11)5-3-7/h2-5,9H,6H2,1H3
- InChI Key
- YJKIALIXRCSISK-UHFFFAOYSA-N
Overview
Methyl 2-chloro-3-(4-chlorophenyl)propanoate (CAS 14437-17-3) is a dichlorinated aromatic ester compound with significant industrial applications and aquatic toxicity concerns. This specialized chemical intermediate belongs to the family of chlorinated phenylpropanoate esters, characterized by its molecular formula C10H10Cl2O2 and molecular weight of 233.09 g/mol. The compound features a methyl ester functional group attached to a propanoic acid backbone that carries both a chlorine substituent and a 4-chlorophenyl group, giving it distinctive reactivity profiles suitable for various synthetic applications. From a safety perspective, methyl 2-chloro-3-(4-chlorophenyl)propanoate is classified under multiple hazard categories, including Acute Toxicity Category 4 and significant environmental concerns with Aquatic Acute 1 and Aquatic Chronic 1 classifications. The compound displays GHS07 and GHS09 pictograms with a "Warning" signal word, indicating both health and environmental hazards that require careful handling protocols. Transportation falls under ADR Class 6.1, reflecting its toxic substance classification. Industrial applications primarily center around its role as a synthetic intermediate in pharmaceutical manufacturing and agrochemical production. The compound's dual chlorine functionality makes it valuable for nucleophilic substitution reactions and cross-coupling processes. It shares structural similarities with other chlorinated aromatic compounds like phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate, though with distinct reactivity patterns due to its ester functionality. The compound finds additional use in specialty chemical synthesis where selective chlorination patterns are required, particularly in the development of bioactive molecules and crop protection agents. OYSI maintains reliable supply chains for methyl 2-chloro-3-(4-chlorophenyl)propanoate to support European industrial customers requiring this specialized chemical intermediate.
Safety & Classification
Acute Tox. 4 *; Acute Tox. 4 *; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2996 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | Chlorfenprop-methyl |
| Marine Pollutant | No |
Frequently Asked Questions
What is methyl 2-chloro-3-(4-chlorophenyl)propanoate?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate is an organic chemical compound with the molecular formula C10H10Cl2O2 and CAS number 14437-17-3. This chlorinated aromatic ester has a molecular weight of 233.09 g/mol and contains two chlorine atoms in its structure. It is classified as a hazardous substance with acute toxicity properties and environmental hazards, requiring careful handling in industrial applications.
What are the physicochemical properties of methyl 2-chloro-3-(4-chlorophenyl)propanoate?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate is a chlorinated organic ester with a molecular weight of 233.09 g/mol. As an ester compound containing chlorinated aromatic groups, it typically exhibits limited water solubility but good solubility in organic solvents. The presence of two chlorine atoms and the aromatic ring structure influence its physical properties, making it stable under normal conditions but requiring specific storage considerations.
What is methyl 2-chloro-3-(4-chlorophenyl)propanoate used for?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its structure makes it valuable for the production of various chemical compounds, particularly in the development of active pharmaceutical ingredients and specialty chemicals. The compound serves as a building block in synthetic pathways where chlorinated aromatic esters are required for further chemical transformations.
How to handle methyl 2-chloro-3-(4-chlorophenyl)propanoate safely?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate requires careful handling due to its Acute Tox. 4 classification. Wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation in work areas to prevent inhalation exposure. Avoid direct skin and eye contact, and implement proper hygiene measures. Handle in controlled environments with appropriate safety protocols due to its hazardous nature.
How to store methyl 2-chloro-3-(4-chlorophenyl)propanoate correctly?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers properly labeled and segregated from incompatible materials. Due to its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1), implement measures to prevent environmental release. Store in accordance with local regulations for toxic substances.
What to do in case of contact with methyl 2-chloro-3-(4-chlorophenyl)propanoate?
In case of skin contact with methyl 2-chloro-3-(4-chlorophenyl)propanoate, immediately remove contaminated clothing and wash affected areas thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention if symptoms develop or persist, and provide the safety data sheet to medical personnel.
How to dispose of methyl 2-chloro-3-(4-chlorophenyl)propanoate properly?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate must be disposed of as hazardous waste through authorized waste management companies. Due to its environmental hazard classification and toxic properties, it cannot be disposed of through regular waste streams. Follow local and national regulations for hazardous waste disposal, ensuring proper documentation and traceability. Consider incineration at licensed facilities capable of handling chlorinated organic compounds.
How to transport methyl 2-chloro-3-(4-chlorophenyl)propanoate?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation. It requires appropriate hazardous goods packaging, labeling, and documentation according to ADR regulations. Vehicles must display proper hazard placards, and drivers need ADR certification. Ensure compliance with all transport regulations for toxic substances and maintain proper emergency response information during transit.
Is methyl 2-chloro-3-(4-chlorophenyl)propanoate subject to specific regulations?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate is subject to REACH registration requirements in Europe and CLP classification as indicated by its GHS07 and GHS09 pictograms with Warning signal word. While not currently identified as a SVHC (Substance of Very High Concern), its Acute Tox. 4 and aquatic hazard classifications subject it to specific handling, storage, and disposal regulations under chemical safety legislation.
Where to buy methyl 2-chloro-3-(4-chlorophenyl)propanoate in Europe?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI provides this substance with proper documentation, safety data sheets, and regulatory compliance for industrial and research applications. Contact OYSI directly for availability, specifications, packaging options, and delivery throughout Europe while ensuring compliance with all applicable regulations.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.