Methyl 2-chloro-3-(4-chlorophenyl)propanoate
C10H10Cl2O2
methyl 2-chloro-3-(4-chlorophenyl)propanoate
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Identification
- CAS Number
- 14437-17-3
- EC Number
- 238-413-5
- UN Number
- 2996
- Index Number
- 607-075-00-4
- PubChem CID
- 26693
Physical-chemical properties
- Molecular Formula
- C10H10Cl2O2
- Molar Mass
- 233.09 g/mol
- IUPAC Name
- methyl 2-chloro-3-(4-chlorophenyl)propanoate
Chemical Identifiers
- InChI
- InChI=1S/C10H10Cl2O2/c1-14-10(13)9(12)6-7-2-4-8(11)5-3-7/h2-5,9H,6H2,1H3
- InChI Key
- YJKIALIXRCSISK-UHFFFAOYSA-N
Overview
Methyl 2-chloro-3-(4-chlorophenyl)propanoate (CAS 14437-17-3) is a dichlorinated aromatic ester compound with significant industrial chemical applications and moderate toxicity properties. This specialized organic compound represents an important class of chlorinated aromatic esters widely utilized in industrial chemical processes. With its molecular formula C10H10Cl2O2 and molecular weight of 233.09 g/mol, methyl 2-chloro-3-(4-chlorophenyl)propanoate exhibits characteristic properties typical of halogenated aromatic compounds. The presence of two chlorine atoms - one on the propanoate chain and another on the phenyl ring - contributes to its unique reactivity profile and chemical stability. The compound is classified under acute toxicity category 4 and presents significant environmental hazards, particularly to aquatic ecosystems where it demonstrates both acute and chronic toxicity. Safety handling requires adherence to ADR class 6.1 transport regulations and appropriate protective measures indicated by GHS07 and GHS09 pictograms. The warning signal word reflects its moderate hazard profile, necessitating proper ventilation, protective equipment, and controlled storage conditions. Primary industrial applications include use as a chemical intermediate in pharmaceutical synthesis, specialty chemical manufacturing, and as a building block for more complex molecular structures. The compound's reactivity makes it valuable in organic synthesis processes where selective chlorination or esterification reactions are required. Its structural similarity to compounds like phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate positions it within the broader family of chlorinated aromatic intermediates used in agrochemical and pharmaceutical industries. OYSI maintains reliable supply chains for methyl 2-chloro-3-(4-chlorophenyl)propanoate, ensuring consistent availability for European industrial customers requiring this specialized chemical intermediate.
Safety & Classification
Acute Tox. 4 *; Acute Tox. 4 *; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2996 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | Chlorfenprop-methyl |
| Marine Pollutant | No |
Frequently Asked Questions
What is methyl 2-chloro-3-(4-chlorophenyl)propanoate?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate is an organic chemical compound with the molecular formula C10H10Cl2O2 and CAS number 14437-17-3. This chlorinated aromatic ester has a molecular weight of 233.09 g/mol and contains two chlorine atoms in its structure. It is classified as a hazardous substance under GHS regulations with acute toxicity and aquatic toxicity properties, requiring careful handling in industrial applications.
What are the physicochemical properties of methyl 2-chloro-3-(4-chlorophenyl)propanoate?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate is a chlorinated organic ester with a molecular weight of 233.09 g/mol. As an aromatic compound containing chlorine substituents, it typically exists as a liquid or solid at room temperature. The presence of both hydrophobic aromatic and chlorinated groups alongside the polar ester functionality influences its solubility characteristics, making it more soluble in organic solvents than in water.
What is methyl 2-chloro-3-(4-chlorophenyl)propanoate used for?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its chlorinated aromatic structure makes it valuable for producing various chemical derivatives through substitution and coupling reactions. The compound serves as a building block in the synthesis of more complex molecules, particularly in the development of pharmaceuticals, agrochemicals, and specialty chemicals requiring chlorinated aromatic frameworks.
How to handle methyl 2-chloro-3-(4-chlorophenyl)propanoate safely?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate requires careful handling due to its Acute Tox. 4 classification. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume extraction systems to prevent inhalation exposure. Avoid skin and eye contact, and ensure emergency washing facilities are readily available. Follow GHS07 pictogram warnings and implement proper containment measures to prevent environmental release.
How to store methyl 2-chloro-3-(4-chlorophenyl)propanoate correctly?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers upright and properly labeled according to GHS requirements. Due to its aquatic toxicity classification, implement secondary containment measures to prevent environmental contamination. Store away from oxidizing agents and bases that could react with the ester functionality.
What to do in case of contact with methyl 2-chloro-3-(4-chlorophenyl)propanoate?
In case of skin contact with methyl 2-chloro-3-(4-chlorophenyl)propanoate, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15-20 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. Seek medical attention if symptoms persist or if significant exposure has occurred, especially given its acute toxicity classification.
How to dispose of methyl 2-chloro-3-(4-chlorophenyl)propanoate properly?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate must be disposed of as hazardous waste through licensed waste management companies due to its acute and aquatic toxicity classifications. Never discharge to sewers, waterways, or soil as it poses significant environmental risks. Collect waste in appropriate containers, clearly label according to hazard classification, and maintain proper documentation. Incineration at licensed high-temperature facilities is typically the preferred disposal method for chlorinated organic compounds.
How to transport methyl 2-chloro-3-(4-chlorophenyl)propanoate?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation. Use UN-approved packaging suitable for Class 6.1 materials and ensure proper hazard labels and documentation accompany shipments. Transport vehicles must comply with ADR requirements for toxic substances, including appropriate placarding and emergency equipment. Drivers require ADR certification for Class 6.1 materials, and emergency response information must be available during transport.
Is methyl 2-chloro-3-(4-chlorophenyl)propanoate subject to specific regulations?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate is regulated under European REACH and CLP regulations due to its hazardous properties. It requires appropriate classification, labeling, and safety data sheets according to GHS standards with GHS07 and GHS09 pictograms. While not currently listed as an SVHC substance, its acute and aquatic toxicity classifications subject it to strict handling, storage, and disposal requirements under environmental protection legislation and workplace safety regulations.
Where to buy methyl 2-chloro-3-(4-chlorophenyl)propanoate in Europe?
Methyl 2-chloro-3-(4-chlorophenyl)propanoate is available through OYSI, a specialized European distributor of technical chemicals and intermediates. OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance for industrial and research applications. As a professional chemical distributor, OYSI ensures quality standards and proper handling procedures for hazardous materials, supporting customers throughout Europe with technical expertise and reliable supply chain management.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.