Diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane

C8H13N2O3PS

diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane

CAS297-97-2
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
297-97-2
EC Number
206-049-6
UN Number
3018
Index Number
015-112-00-5
PubChem CID
9272

Physical-chemical properties

Molecular Formula
C8H13N2O3PS
Molar Mass
248.24 g/mol
IUPAC Name
diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane

Chemical Identifiers

InChI
InChI=1S/C8H13N2O3PS/c1-3-11-14(15,12-4-2)13-8-7-9-5-6-10-8/h5-7H,3-4H2,1-2H3
InChI Key
IRVDMKJLOCGUBJ-UHFFFAOYSA-N

Overview

Diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane (CAS 297-97-2) is an organophosphorus compound with high acute toxicity and specialized industrial applications. This organophosphorus compound represents a complex molecular structure combining pyrazine and phosphorus-sulfur functionalities, resulting in a substance with distinctive chemical properties and significant safety considerations. With its molecular formula C8H13N2O3PS and molecular weight of 248.24 g/mol, this compound belongs to the lambda5-phosphane family, characterized by the presence of both ethoxy substituents and a pyrazinyloxy group attached to the central phosphorus atom. The compound exhibits extremely high acute toxicity, classified under Acute Tox. 1 and Acute Tox. 2 categories, requiring the GHS06 skull and crossbones pictogram and "Danger" signal word. Its ADR classification as Class 6.1 indicates toxic substances requiring specialized handling, storage, and transportation protocols. The unique structural features, including the sulfanylidene group and pyrazine ring system, contribute to its specific reactivity profile and biological activity. Industrial applications primarily focus on specialized chemical synthesis where the compound serves as an intermediate in pharmaceutical research, agrochemical development, and advanced materials production. The pyrazine moiety provides nitrogen-containing heterocyclic functionality, while the organophosphorus component offers unique reactivity patterns distinct from related compounds such as 2-[bis(dimethylamino)phosphoryl]-5-phenyl-1,2,4-triazol-3-amine, which features different heterocyclic systems and phosphoryl functionalities. Due to its high toxicity profile, this compound requires expert handling and is typically utilized in controlled research environments and specialized manufacturing processes. OYSI maintains availability of this technical-grade compound for qualified industrial customers requiring certified organophosphorus intermediates.

Safety & Classification

Danger
Classification:

Acute Tox. 1; Acute Tox. 2 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H310

Fatal in contact with skin.

H300

Fatal if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Fatal

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3018
ADR Class6.1
Packing GroupI
Tunnel CodeC/E
Proper Shipping NameThionazin (ISO)
Marine PollutantNo

Frequently Asked Questions

What is diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane?

Diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane is an organophosphorus compound with the molecular formula C8H13N2O3PS and CAS number 297-97-2. This chemical substance has a molecular weight of 248.24 g/mol and contains phosphorus, sulfur, nitrogen, and oxygen atoms in its structure. It is classified as highly toxic with acute toxicity classifications of Category 1 and 2, requiring extreme caution during handling and use.

What are the physicochemical properties of diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane?

Diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane is a chemical compound with a molecular mass of 248.24 g/mol and the molecular formula C8H13N2O3PS. As an organophosphorus compound containing ethoxy groups and a pyrazine ring, it likely exhibits moderate polarity. Specific physical properties such as melting point, boiling point, and solubility characteristics would need to be determined through laboratory analysis or supplier specifications.

What is diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane used for?

Diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane is primarily used as a specialized chemical intermediate in pharmaceutical and agrochemical synthesis. Its organophosphorus structure makes it valuable for research applications and as a building block in the development of bioactive compounds. Due to its high toxicity classification, its use is restricted to professional industrial applications with appropriate safety measures and qualified personnel handling.

How to safely handle diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane?

Diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane requires extreme safety precautions due to its Acute Toxicity Categories 1 and 2 classification. Personnel must wear full personal protective equipment including chemical-resistant gloves, protective clothing, eye protection, and respiratory protection. Handle only in well-ventilated areas or under fume hoods, avoid skin contact and inhalation, and ensure trained personnel only perform manipulations following strict safety protocols.

How to properly store diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane?

Diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Due to its high toxicity classification, storage requires secure, labeled containers in restricted access areas with appropriate secondary containment. The storage area should be equipped with emergency response materials and maintain stable temperature conditions to prevent degradation of this sensitive organophosphorus compound.

What to do in case of contact with diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane?

Immediate emergency response is critical due to the substance's high acute toxicity. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting. Seek immediate medical attention in all cases and provide safety data sheet to medical personnel.

How to properly dispose of diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane waste?

Diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane waste must be disposed of through licensed hazardous waste disposal companies due to its high toxicity classification. The substance cannot be disposed of in regular waste streams or sewage systems. Waste containers must be properly labeled, sealed, and stored in designated hazardous waste areas until collection. Disposal must comply with local, national, and EU waste regulations for toxic substances.

How to transport diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane?

Diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane is classified under ADR Class 6.1 (Toxic substances), Packing Group I, indicating the highest level of toxicity for transport purposes. Transportation requires specialized packaging meeting UN specifications, proper hazard labeling with GHS06 pictograms, and transport documents. Only authorized carriers trained in hazardous materials transport can handle shipments, following strict ADR regulations for toxic substances.

Is diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane subject to specific regulations?

Diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane is subject to comprehensive chemical regulations including REACH registration requirements, CLP classification as Acute Tox. 1 and 2 with GHS06 pictogram, and ADR transport regulations. While not currently listed as an SVHC substance, its high toxicity classification means it requires strict compliance with occupational safety regulations, waste disposal laws, and potentially export/import controls depending on jurisdiction and application.

Where to buy diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane in Europe?

Diethoxy-pyrazin-2-yloxy-sulfanylidene-lambda5-phosphane is available through OYSI, a European distributor of specialty chemicals. As a highly toxic substance requiring specialized handling and documentation, procurement is limited to qualified industrial customers with appropriate safety infrastructure and regulatory compliance. OYSI provides technical support and ensures proper packaging and transport according to ADR Class 6.1 requirements for European distribution.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.