4-tritylmorpholine
C23H23NO
Consulting for 4-tritylmorpholine
Our experts support you with application, dosage, and compliance.
Identification
- CAS Number
- 1420-06-0
- EC Number
- 215-812-2
- UN Number
- 2588
- Index Number
- 613-052-00-X
- PubChem CID
- 14993
Physical-chemical properties
- Molecular Formula
- C23H23NO
- Molar Mass
- 329.40 g/mol
- IUPAC Name
- 4-tritylmorpholine
Chemical Identifiers
- InChI
- InChI=1S/C23H23NO/c1-4-10-20(11-5-1)23(21-12-6-2-7-13-21,22-14-8-3-9-15-22)24-16-18-25-19-17-24/h1-15H,16-19H2
- InChI Key
- ZJMLMBICUVVJDX-UHFFFAOYSA-N
Overview
4-tritylmorpholine (CAS 1420-06-0) is an organic nitrogen compound with morpholine functionality and trityl protection group properties. This specialized chemical compound represents an important class of protected morpholine derivatives widely used in pharmaceutical synthesis and organic chemistry applications. With its molecular formula C23H23NO and molecular weight of 329.4 g/mol, 4-tritylmorpholine combines the six-membered morpholine ring structure with a bulky trityl (triphenylmethyl) protecting group attached to the nitrogen atom. This structural arrangement provides both steric hindrance and chemical stability, making it particularly valuable in multi-step synthetic processes where selective protection and deprotection of the morpholine nitrogen is required. The compound exhibits moderate acute toxicity (Acute Tox. 4) and significant aquatic toxicity, requiring careful handling procedures and appropriate safety measures during use. The presence of GHS07 and GHS09 pictograms indicates both health hazards and environmental concerns, while its ADR Class 6.1 classification necessitates proper transport protocols for toxic substances. These safety characteristics distinguish it from simpler morpholine derivatives and require more stringent handling compared to compounds like dimethoxy-(3-methyl-4-nitrophenoxy)-sulfanylidene-lambda5-phosphane, which may have different toxicity profiles. Primary industrial applications include pharmaceutical intermediate synthesis, where the trityl group serves as a temporary protecting group during complex molecule construction, custom synthesis projects requiring selective nitrogen protection, and specialized research applications in medicinal chemistry. The compound's unique structural features make it particularly suitable for developing novel therapeutic compounds where controlled reactivity at the morpholine nitrogen is essential. OYSI maintains reliable supply channels for 4-tritylmorpholine to support European pharmaceutical and chemical research industries.
Safety & Classification
Acute Tox. 4 *; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2588 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | Trifenmorph (ISO) |
| Marine Pollutant | No |
Frequently Asked Questions
What is 4-tritylmorpholine?
4-tritylmorpholine is an organic chemical compound with the molecular formula C23H23NO and CAS number 1420-06-0. It belongs to the morpholine family of heterocyclic compounds, featuring a trityl (triphenylmethyl) group attached to the nitrogen atom of the morpholine ring. With a molecular weight of 329.4 g/mol, this compound is classified as moderately hazardous with acute toxicity and aquatic toxicity properties.
What are the physicochemical properties of 4-tritylmorpholine?
4-tritylmorpholine is a solid organic compound at room temperature with a molecular weight of 329.4 g/mol. The presence of the bulky trityl group significantly influences its physical properties, including solubility and melting point. Its molecular structure combines the polar morpholine ring with three aromatic phenyl rings, creating a compound with both polar and non-polar characteristics that affect its interaction with solvents and other chemicals.
What is 4-tritylmorpholine used for?
4-tritylmorpholine serves primarily as an intermediate in pharmaceutical synthesis and organic chemistry research. The trityl group acts as a protecting group for the morpholine nitrogen, allowing selective reactions at other sites of complex molecules. It is commonly used in the synthesis of pharmaceutical compounds, fine chemicals, and as a reagent in academic and industrial research laboratories for developing new chemical entities and drug candidates.
How to handle 4-tritylmorpholine safely?
4-tritylmorpholine requires careful handling due to its Acute Tox. 4 classification and environmental hazards. Workers must wear appropriate personal protective equipment including gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid direct skin contact and ingestion, and ensure proper training on chemical safety procedures before handling this substance.
How to store 4-tritylmorpholine correctly?
4-tritylmorpholine should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly sealed to prevent moisture absorption and contamination. Store separately from incompatible materials such as strong acids, bases, and oxidizing agents. Ensure storage areas are equipped with appropriate spill containment measures and emergency response equipment, following local chemical storage regulations.
What to do in case of contact with 4-tritylmorpholine?
In case of skin contact with 4-tritylmorpholine, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If eye contact occurs, rinse immediately with clean water for at least 15 minutes and seek medical attention. In case of inhalation, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention while providing the safety data sheet.
How to dispose of 4-tritylmorpholine properly?
4-tritylmorpholine must be disposed of as hazardous chemical waste in accordance with local and national environmental regulations. Due to its aquatic toxicity classification (Aquatic Acute 1, Aquatic Chronic 1), it cannot be discharged into water systems or regular waste streams. Contact licensed hazardous waste disposal companies for proper collection and treatment. Small laboratory quantities may require special packaging and labeling before disposal through institutional waste management programs.
How to transport 4-tritylmorpholine?
4-tritylmorpholine is classified under ADR as Class 6.1 (toxic substances), Packing Group III, requiring specific transport regulations compliance. Packages must bear proper hazard labels including GHS07 and GHS09 pictograms with 'Warning' signal word. Transportation should be handled by certified carriers familiar with dangerous goods regulations. Ensure proper documentation, emergency response information, and appropriate packaging that meets UN specification requirements for this hazard class.
Is 4-tritylmorpholine subject to special regulations?
4-tritylmorpholine is subject to standard chemical regulations including REACH registration requirements in the European Union and CLP classification for hazard communication. It is not currently listed as a Substance of Very High Concern (SVHC). Companies must comply with occupational safety regulations, environmental protection laws, and proper labeling requirements. Users should maintain safety data sheets and ensure proper risk assessments are conducted before use in workplace settings.
Where to buy 4-tritylmorpholine in Europe?
4-tritylmorpholine is available through OYSI, a specialized European distributor of technical chemicals serving industrial and research customers across Europe. OYSI provides quality chemical products with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical supplier, OYSI ensures reliable supply chains and technical support for customers requiring this specialized morpholine derivative for their applications in pharmaceutical and chemical industries.
Services for 4-tritylmorpholine
Order 4-tritylmorpholine
Fast delivery across Europe
SDS Service
Request Safety Data Sheet for 4-tritylmorpholine
Technical Consulting
Application advice for 4-tritylmorpholine
REACH Safety Data Sheet
REACH Compliance Service
Digital Product Passport
EU-compliant product documentation
ADR Consulting for 4-tritylmorpholine
4-tritylmorpholine is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.