(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane

C8H9ClNO5PS

CAS500-28-7
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
500-28-7
EC Number
207-902-5
UN Number
3018
Index Number
015-042-00-5
PubChem CID
10372

Physical-chemical properties

Molecular Formula
C8H9ClNO5PS
Molar Mass
297.65 g/mol
IUPAC Name
(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane

Chemical Identifiers

InChI
InChI=1S/C8H9ClNO5PS/c1-13-16(17,14-2)15-6-3-4-8(10(11)12)7(9)5-6/h3-5H,1-2H3
InChI Key
NZNRRXXETLSZRO-UHFFFAOYSA-N

Overview

(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane (CAS 500-28-7) is an organophosphorus compound featuring phenoxy and thiophosphoryl functional groups with notable toxicological properties. This specialized organophosphorus derivative represents an important class of chemical intermediates characterized by its unique molecular structure combining phosphorus-sulfur bonding with halogenated nitrophenyl substituents. The compound exhibits a molecular formula of C8H9ClNO5PS with a molecular weight of 297.65 g/mol, reflecting its complex multi-functional architecture. Its EC number 207-902-5 confirms its established regulatory status within European chemical commerce. The substance presents significant safety considerations, classified under multiple acute toxicity categories (Acute Tox. 4) across different exposure routes, necessitating careful handling protocols. Environmental hazard classifications include both acute and chronic aquatic toxicity (Aquatic Acute 1, Aquatic Chronic 1), requiring appropriate containment and disposal measures. Transportation falls under ADR Class 6.1, indicating toxic substance classification for logistics purposes. Industrial applications typically involve its use as a chemical intermediate in pharmaceutical synthesis, agricultural chemical production, and specialized organic transformations where phosphorus-containing building blocks are required. Its structural similarity to compounds like 4-bromo-2-chloro-1-[ethoxy(propylsulfanyl)phosphoryl]oxybenzene suggests potential applications in developing phosphorylated aromatic derivatives. The presence of both electron-withdrawing groups (nitro, chloro) and the phosphorothioate moiety makes it valuable for creating compounds with specific reactivity profiles. Professional handling requires adherence to GHS07 and GHS09 pictogram warnings, emphasizing both health hazards and environmental concerns. OYSI maintains reliable supply chains for this technical-grade organophosphorus compound, supporting European chemical manufacturing and research applications.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3018
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameChlorthion
Marine PollutantNo

Frequently Asked Questions

What is (3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane?

(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane is an organophosphorus compound with CAS number 500-28-7 and molecular formula C8H9ClNO5PS. This chemical substance has a molecular weight of 297.65 g/mol and belongs to the class of phosphane derivatives containing chloro and nitro functional groups. It is classified as moderately toxic and environmentally hazardous, requiring careful handling and appropriate safety measures during use.

What are the physicochemical properties of (3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane?

(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane is a chemical compound with a molecular weight of 297.65 g/mol and formula C8H9ClNO5PS. The substance contains multiple functional groups including chloro, nitro, and phosphane moieties that influence its chemical behavior. Specific physical properties such as melting point, boiling point, and solubility depend on its molecular structure and intermolecular interactions, requiring consultation of detailed technical datasheets for precise values.

What is (3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane used for?

(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane is typically used as a specialized chemical intermediate in organic synthesis and pharmaceutical applications. As an organophosphorus compound, it may serve as a reagent in chemical research, analytical chemistry, or as a building block for more complex molecular structures. Its specific applications depend on the unique reactivity provided by its chloro, nitro, and phosphane functional groups in various chemical transformations.

How to handle (3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane safely?

(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane requires careful handling due to its Acute Tox. 4 classification and warning signal word. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and appropriate respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and ensure proper training on emergency procedures before handling this moderately toxic substance.

How to store (3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane correctly?

(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from incompatible materials. Given its toxic and environmentally hazardous properties, storage areas must be secure and properly labeled with appropriate GHS pictograms (GHS07, GHS09). Containers should be kept away from heat sources, direct sunlight, and areas accessible to unauthorized personnel to prevent accidental exposure or environmental release.

What to do in case of contact with (3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane?

Immediate action is required in case of contact with (3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane due to its toxic properties. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with water and seek medical attention. If inhaled, move to fresh air and seek medical advice. For ingestion, do not induce vomiting and contact poison control immediately.

How to dispose of (3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane appropriately?

(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane must be disposed of as hazardous waste due to its toxic and environmentally harmful properties indicated by GHS07 and GHS09 pictograms. Disposal should be conducted through licensed hazardous waste disposal companies in accordance with local, national, and EU regulations. Never dispose of this substance in regular waste streams, sewers, or the environment, as it poses significant risks to aquatic life and ecosystems.

How to transport (3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane?

(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Transport must be conducted by qualified personnel with appropriate training in hazardous materials handling. Proper shipping papers, emergency response information, and compatible packaging materials are mandatory for legal and safe transportation across European borders.

Is (3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane subject to specific regulations?

(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane is subject to standard EU chemical regulations including REACH registration requirements and CLP classification obligations. The substance is not currently listed as SVHC (Substance of Very High Concern), but its Acute Tox. 4 and aquatic toxicity classifications require compliance with worker protection and environmental safety regulations. Users must ensure proper risk assessments, safety data sheet provision, and adherence to occupational exposure limits where applicable.

Where to buy (3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane in Europe?

(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane can be purchased from OYSI, a specialized European distributor of technical chemical products. OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance support for professional and industrial applications. As a specialized chemical requiring careful handling, availability may be subject to regulatory requirements and intended use verification. Contact OYSI directly for specific quantities, specifications, and delivery arrangements across European markets.

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(3-chloro-4-nitrophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane is a dangerous good. We support you with labeling, packaging, and transport documentation.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.