2-piperidin-1-ylbenzonitrile

2-piperidin-1-ylbenzonitrile is an organic compound with the molecular formula C12H14N2 and molecular weight of 186.25 g/mol. This chemical features a benzonitrile core structure substituted with a piperidine ring at the ortho position. It is classified under CAS number 72752-52-4 and belongs to the category of nitrogen-containing heterocyclic compounds, combining both aromatic and saturated ring systems in its molecular structure.

2-piperidin-1-ylbenzonitrile is a stable organic compound with a molecular weight of 186.25 g/mol. The molecule contains both a benzonitrile group and a saturated piperidine ring, which influences its physicochemical behavior. As a substituted benzonitrile derivative, it typically exhibits moderate polarity due to the cyano group, while the piperidine substitution affects its solubility profile and intermolecular interactions.

2-piperidin-1-ylbenzonitrile serves as an important intermediate in pharmaceutical and fine chemical synthesis. The compound's unique structure, combining piperidine and benzonitrile moieties, makes it valuable for developing various bioactive molecules and pharmaceutical compounds. It is primarily used in research and development applications, particularly in medicinal chemistry where the piperidine ring system is frequently incorporated into drug molecules for its favorable pharmacological properties.

2-piperidin-1-ylbenzonitrile should be handled with standard laboratory safety precautions including wearing appropriate personal protective equipment such as safety glasses, gloves, and lab coats. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. While it has no specific signal word under GHS classification, proper chemical hygiene practices should be followed, including avoiding direct skin and eye contact and preventing ingestion.

2-piperidin-1-ylbenzonitrile should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and direct sunlight. The storage area should be secure and accessible only to trained personnel. As with most organic chemicals, it should be kept away from incompatible materials such as strong oxidizing agents. Proper labeling and inventory management should be maintained to ensure product integrity and traceability.

In case of skin contact with 2-piperidin-1-ylbenzonitrile, immediately wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, rinse thoroughly with clean water for several minutes and remove contact lenses if present and easily removable. If the substance is inhaled, move the person to fresh air immediately. If ingested, do not induce vomiting and seek medical attention. Always consult safety data sheets for specific first aid measures.

2-piperidin-1-ylbenzonitrile must be disposed of in accordance with local, national, and international waste regulations. Due to its Aquatic Chronic 2 classification, special attention should be paid to preventing environmental release. The compound should be collected and disposed of through licensed waste management facilities capable of handling organic chemical waste. Never dispose of it down drains or in regular waste streams, as this could cause environmental contamination.

2-piperidin-1-ylbenzonitrile is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Shipments must comply with ADR requirements including proper packaging specifications, hazard labels, and transport documentation. Only certified carriers experienced in handling chemical products should be used for transportation to ensure regulatory compliance and safety.

2-piperidin-1-ylbenzonitrile is subject to standard chemical regulations including REACH registration requirements in the European Union. It is classified under the CLP Regulation with hazard class Aquatic Chronic 2, requiring appropriate labeling with GHS09 pictogram. The compound is not listed as a Substance of Very High Concern (SVHC). Users must comply with occupational health and safety regulations, environmental protection laws, and proper chemical management practices according to their local jurisdiction.

2-piperidin-1-ylbenzonitrile is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides reliable supply chains and regulatory compliance support for customers across Europe. As a professional chemical distributor, OYSI ensures proper handling, storage, and documentation of this compound. Contact OYSI directly for availability, specifications, and delivery options tailored to your specific requirements and location within Europe.