9-hydroxyfluorene-9-carboxylic acid

C14H10O3

CAS467-69-6
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt

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Identification

CAS Number
467-69-6
EC Number
207-397-1
UN Number
3077
Index Number
607-234-00-8
PubChem CID
10087

Physical-chemical properties

Molecular Formula
C14H10O3
Molar Mass
226.23 g/mol
IUPAC Name
9-hydroxyfluorene-9-carboxylic acid

Chemical Identifiers

InChI
InChI=1S/C14H10O3/c15-13(16)14(17)11-7-3-1-5-9(11)10-6-2-4-8-12(10)14/h1-8,17H,(H,15,16)
InChI Key
GXAMYUGOODKVRM-UHFFFAOYSA-N

Overview

9-hydroxyfluorene-9-carboxylic acid (CAS 467-69-6) is a fluorene derivative featuring both hydroxyl and carboxyl functional groups at the C9 position. This organic compound represents a significant member of the fluorene family, distinguished by its dual functionality through the presence of both carboxylic acid and hydroxyl groups attached to the same carbon atom. With a molecular formula of C14H10O3 and molecular weight of 226.23 g/mol, this crystalline substance exhibits unique chemical properties that make it valuable in various industrial applications. The compound's structure combines the rigid fluorene backbone with polar functional groups, resulting in distinctive solubility characteristics and reactivity patterns. From a safety perspective, 9-hydroxyfluorene-9-carboxylic acid is classified under Aquatic Chronic 2 hazard category, requiring appropriate environmental precautions during handling and disposal. The compound falls under ADR Class 9 for transportation purposes and displays the GHS09 pictogram, indicating potential environmental hazards. Proper storage conditions and handling protocols should be implemented to minimize environmental impact and ensure workplace safety. The compound finds applications in pharmaceutical intermediates synthesis, where its dual functionality enables complex molecular transformations. It serves as a building block in organic synthesis and specialty chemical manufacturing. Research applications include its use in developing fluorescent compounds and advanced materials. The structural similarity to other fluorene derivatives like 4-[9-(4-amino-3-chlorophenyl)fluoren-9-yl]-2-chloroaniline makes it valuable for comparative studies in medicinal chemistry and materials science. OYSI maintains reliable supply chains for 9-hydroxyfluorene-9-carboxylic acid, ensuring consistent availability for European industrial customers requiring high-quality chemical intermediates.

Safety & Classification

Classification:

Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameFlurenol (ISO)
Marine PollutantNo

Frequently Asked Questions

What is 9-hydroxyfluorene-9-carboxylic acid?

9-hydroxyfluorene-9-carboxylic acid is an organic compound with the molecular formula C14H10O3 and CAS number 467-69-6. This chemical belongs to the fluorene family and features both hydroxyl and carboxylic acid functional groups attached to the fluorene backbone. With a molecular weight of 226.23 g/mol, it is classified as having chronic aquatic toxicity and requires careful environmental consideration during use and disposal.

What are the physicochemical properties of 9-hydroxyfluorene-9-carboxylic acid?

9-hydroxyfluorene-9-carboxylic acid is a solid crystalline compound at room temperature with the molecular formula C14H10O3. The presence of both hydroxyl and carboxylic acid groups makes it moderately polar, affecting its solubility characteristics. As a fluorene derivative, it typically appears as a white to off-white crystalline powder and exhibits stability under normal storage conditions when kept away from strong bases and oxidizing agents.

What is 9-hydroxyfluorene-9-carboxylic acid used for?

9-hydroxyfluorene-9-carboxylic acid is primarily used as a chemical intermediate in pharmaceutical and fine chemical synthesis. Its unique structure with both hydroxyl and carboxylic acid functionalities makes it valuable for developing complex organic molecules. The compound serves as a building block in medicinal chemistry research and in the synthesis of specialized materials where the fluorene backbone provides specific optical or electronic properties.

How to handle 9-hydroxyfluorene-9-carboxylic acid safely?

9-hydroxyfluorene-9-carboxylic acid should be handled with standard laboratory safety equipment including safety glasses, gloves, and lab coats. Work in well-ventilated areas to minimize dust exposure and avoid direct skin contact. While it carries the GHS09 pictogram for environmental hazards, basic personal protective equipment is sufficient for safe handling. Always wash hands thoroughly after use and avoid releasing the substance into the environment due to its aquatic toxicity classification.

How to store 9-hydroxyfluorene-9-carboxylic acid correctly?

9-hydroxyfluorene-9-carboxylic acid should be stored in a cool, dry place away from direct sunlight and heat sources. Keep containers tightly sealed to prevent moisture absorption and contamination. Store away from strong bases, oxidizing agents, and reducing agents to prevent unwanted reactions. The storage area should be well-ventilated and equipped with appropriate spill containment measures to prevent environmental release due to its aquatic chronic toxicity classification.

What to do in case of contact with 9-hydroxyfluorene-9-carboxylic acid?

In case of skin contact with 9-hydroxyfluorene-9-carboxylic acid, immediately wash the affected area with plenty of soap and water for at least 15 minutes. If eye contact occurs, flush thoroughly with water for 15 minutes and seek medical attention. In case of inhalation, move to fresh air immediately. If ingested, do not induce vomiting and seek medical advice. Always consult the safety data sheet for specific first aid measures and contact emergency services if serious symptoms develop.

How to dispose of 9-hydroxyfluorene-9-carboxylic acid appropriately?

9-hydroxyfluorene-9-carboxylic acid must be disposed of through authorized hazardous waste disposal channels due to its Aquatic Chronic 2 classification. Never dispose of this substance down drains or into the environment. Contact licensed waste management companies that specialize in chemical disposal. Small quantities can often be incinerated at high temperatures in specialized facilities. Always comply with local, national, and European waste regulations when planning disposal activities.

How to transport 9-hydroxyfluorene-9-carboxylic acid?

9-hydroxyfluorene-9-carboxylic acid is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III. This classification requires appropriate packaging and labeling for transport within Europe. Use UN-approved packaging and ensure proper documentation accompanies shipments. The substance must be transported by carriers qualified to handle Class 9 dangerous goods, with appropriate emergency information readily available during transit. Environmental precautions are essential due to its aquatic toxicity.

Is 9-hydroxyfluorene-9-carboxylic acid subject to specific regulations?

9-hydroxyfluorene-9-carboxylic acid is subject to standard European chemical regulations including REACH and CLP. It is not currently listed as a Substance of Very High Concern (SVHC), but its Aquatic Chronic 2 classification requires environmental risk assessment. Users must comply with occupational exposure limits and environmental discharge restrictions. The substance falls under standard industrial chemical regulations for handling, storage, and transport within the European Union framework.

Where to buy 9-hydroxyfluorene-9-carboxylic acid in Europe?

9-hydroxyfluorene-9-carboxylic acid is available through OYSI, a specialized European distributor of fine chemicals and pharmaceutical intermediates. As an established chemical supplier, OYSI can provide this compound with appropriate documentation including certificates of analysis and safety data sheets. Contact OYSI directly for availability, specifications, and pricing information. Their expertise in chemical distribution ensures proper handling and compliance with European regulations throughout the supply chain.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.