1-(2-chloro-4-pyridinyl)-3-phenylurea

1-(2-chloro-4-pyridinyl)-3-phenylurea is an organic compound with the molecular formula C12H10ClN3O and CAS number 68157-60-8. This urea derivative contains both pyridine and phenyl functional groups with a chlorine substituent. With a molecular weight of 247.68 g/mol, it is classified as a suspected carcinogen (Category 2) and poses chronic aquatic toxicity risks. The compound requires careful handling due to its hazardous properties indicated by GHS08 and GHS09 pictograms.

1-(2-chloro-4-pyridinyl)-3-phenylurea is a solid organic compound at room temperature with a molecular weight of 247.68 g/mol. The presence of chlorine, nitrogen atoms, and aromatic rings influences its polarity and solubility characteristics. As a substituted urea derivative, it likely exhibits limited water solubility but better solubility in organic solvents. The compound's stability and melting point are influenced by intermolecular hydrogen bonding typical of urea compounds and π-π interactions between aromatic rings.

1-(2-chloro-4-pyridinyl)-3-phenylurea is primarily used as a chemical intermediate in pharmaceutical and agrochemical synthesis. Its unique structure containing both pyridine and phenyl groups makes it valuable for developing bioactive compounds. The compound may serve as a building block for herbicides, pharmaceuticals, or other specialty chemicals. Its applications are typically limited to professional industrial settings due to its hazardous classification, requiring specialized knowledge and safety measures for proper utilization in chemical manufacturing processes.

1-(2-chloro-4-pyridinyl)-3-phenylurea requires careful handling due to its suspected carcinogenic properties. Essential personal protective equipment includes nitrile gloves, safety goggles, and respiratory protection to prevent inhalation exposure. Work should be conducted in well-ventilated areas or under fume hoods to minimize airborne exposure. Avoid skin contact and ingestion completely. Handle containers carefully to prevent spills, and ensure all personnel are trained in proper chemical handling procedures before working with this substance.

1-(2-chloro-4-pyridinyl)-3-phenylurea should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly sealed to prevent moisture absorption and contamination. Store separately from incompatible materials such as strong oxidizers, acids, and bases. The storage area should be equipped with appropriate spill containment measures and restricted access due to the compound's carcinogenic classification. Maintain proper inventory records and ensure containers are properly labeled according to CLP regulations.

Immediate action is required upon contact with 1-(2-chloro-4-pyridinyl)-3-phenylurea due to its hazardous nature. For skin contact, remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical help. Always consult a physician and provide the safety data sheet.

1-(2-chloro-4-pyridinyl)-3-phenylurea must be disposed of as hazardous waste through licensed waste management companies due to its carcinogenic classification. Never dispose of this substance in regular trash, sewers, or the environment as it poses chronic aquatic toxicity risks. Collect waste in appropriate containers, clearly labeled with contents and hazard information. Disposal must comply with local, national, and EU waste regulations including the Waste Framework Directive. Maintain proper waste disposal documentation and certificates for regulatory compliance.

1-(2-chloro-4-pyridinyl)-3-phenylurea is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to ADR regulations. Packages must bear proper shipping names, UN numbers, and hazard labels. Transportation should only be handled by trained personnel familiar with dangerous goods regulations. Ensure proper vehicle placarding and carry appropriate transport documents including safety data sheets during shipment across European borders.

1-(2-chloro-4-pyridinyl)-3-phenylurea is subject to multiple regulatory frameworks including REACH registration requirements for importers and manufacturers. Under CLP regulation, it must be classified and labeled with GHS08 and GHS09 pictograms and 'Warning' signal word due to its carcinogenic and aquatic toxicity properties. While not currently listed as a SVHC substance, its suspected carcinogenic properties may trigger future regulatory restrictions. Companies handling this substance must ensure compliance with occupational health regulations and maintain appropriate risk assessments.

1-(2-chloro-4-pyridinyl)-3-phenylurea is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the continent. As a professional chemical supplier, OYSI ensures full regulatory compliance including proper documentation, safety data sheets, and transport classification for this hazardous substance. Our technical support team provides guidance on safe handling and regulatory requirements. Contact OYSI directly to discuss availability, quantities, and delivery options for your specific industrial applications while ensuring all safety protocols are maintained.