1-(2-chloro-4-pyridinyl)-3-phenylurea

1-(2-chloro-4-pyridinyl)-3-phenylurea is an organic chemical compound with the molecular formula C12H10ClN3O and CAS number 68157-60-8. This urea derivative features a chlorinated pyridine ring connected to a phenyl group through a urea linkage, giving it a molecular weight of 247.68 g/mol. It is classified as a category 2 carcinogen and chronic aquatic toxicant category 2 under GHS classification.

1-(2-chloro-4-pyridinyl)-3-phenylurea is a solid organic compound at room temperature with a molecular weight of 247.68 g/mol. The compound contains chlorine, nitrogen, and oxygen functional groups within its aromatic structure. Specific physical properties such as melting point, solubility, and appearance may vary depending on the grade and purity of the material supplied.

1-(2-chloro-4-pyridinyl)-3-phenylurea is primarily used as an intermediate in pharmaceutical and agrochemical synthesis. This compound serves as a building block for the development of various active ingredients due to its unique structural features combining pyridine and phenyl groups. It may also be utilized in research and development applications within the chemical industry for specialized synthesis processes.

1-(2-chloro-4-pyridinyl)-3-phenylurea requires careful handling due to its carcinogenic properties (Carc. 2). Essential safety measures include wearing appropriate personal protective equipment such as gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume extraction. Avoid skin contact, inhalation, and ingestion. Follow strict hygiene protocols and wash hands thoroughly after handling.

1-(2-chloro-4-pyridinyl)-3-phenylurea should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly closed and properly labeled according to GHS requirements with warning pictograms GHS08 and GHS09. Storage areas should be secure and accessible only to trained personnel due to the carcinogenic classification of this substance.

Immediate action is required upon contact with 1-(2-chloro-4-pyridinyl)-3-phenylurea due to its hazardous nature. For skin contact, wash immediately with plenty of soap and water. In case of eye contact, rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention promptly. Always consult the safety data sheet for detailed first aid measures.

1-(2-chloro-4-pyridinyl)-3-phenylurea must be disposed of as hazardous waste according to local and EU regulations due to its carcinogenic and aquatic toxicity properties. Contact licensed waste disposal companies specialized in hazardous chemical waste. Never dispose of this substance through regular waste streams or pour down drains. Maintain proper documentation of disposal activities as required by environmental regulations.

1-(2-chloro-4-pyridinyl)-3-phenylurea is classified as ADR Class 9 (miscellaneous dangerous substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to international dangerous goods regulations. Transportation must comply with ADR/RID requirements for road and rail transport, with proper shipping papers and emergency response information provided to carriers.

1-(2-chloro-4-pyridinyl)-3-phenylurea is subject to REACH and CLP regulations in Europe due to its hazardous properties. While not currently listed as a Substance of Very High Concern (SVHC), its carcinogenic classification (Carc. 2) requires compliance with occupational exposure limits and worker protection measures. Users must follow proper risk assessment procedures and implement appropriate risk management measures as per regulatory requirements.

1-(2-chloro-4-pyridinyl)-3-phenylurea is available through OYSI, a specialized European distributor of chemical products. OYSI provides professional-grade chemicals with proper documentation, safety data sheets, and regulatory compliance support. As a trusted supplier in the European market, OYSI ensures quality products and reliable service for industrial and research applications requiring this specialized chemical intermediate.