Oxolan-2-ylmethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate

Oxolan-2-ylmethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate is a complex organic compound with CAS number 200509-41-7 and molecular formula C22H21ClN2O5. This chemical features a quinoxaline ring system with chlorine substitution, connected through phenoxy linkages to a propanoate ester with a tetrahydrofuran (oxolan) group. With a molecular weight of 428.9 g/mol, it presents significant safety concerns including carcinogenic and reproductive toxicity properties, requiring careful handling in professional applications.

Oxolan-2-ylmethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate is an organic solid with molecular formula C22H21ClN2O5 and molecular weight 428.9 g/mol. The compound contains multiple functional groups including quinoxaline, phenoxy ethers, and ester linkages, which influence its physical properties. Due to its complex aromatic structure and polar functional groups, it likely exhibits limited water solubility but good solubility in organic solvents. Specific physical data such as melting point, density, and exact solubility parameters require experimental determination.

Oxolan-2-ylmethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate is primarily used as a specialized chemical intermediate in pharmaceutical and agrochemical research and development. The quinoxaline core structure suggests potential applications in developing bioactive compounds, particularly in medicinal chemistry for creating pharmaceutical precursors. Its complex molecular architecture makes it valuable for synthetic organic chemistry applications, potentially serving as a building block for more complex therapeutic agents or agricultural chemicals in specialized industrial processes.

Oxolan-2-ylmethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate requires strict safety protocols due to its carcinogenic and reproductive toxicity classification. Workers must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection when handling this substance. Work should be conducted in well-ventilated areas or under fume hood extraction to minimize inhalation exposure. Avoid skin and eye contact, and implement proper hygiene measures including immediate washing after potential contact. Only trained personnel should handle this material following established safety procedures.

Oxolan-2-ylmethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Given its hazardous classification, storage must be in appropriate secondary containment within designated chemical storage areas with restricted access. The compound should be kept in original containers with intact labeling, separated from incompatible materials such as strong oxidizers and bases. Storage areas should have appropriate spill control measures and emergency equipment readily available for safe handling of any accidental releases.

Immediate action is required following contact with oxolan-2-ylmethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate due to its toxic properties. For skin contact, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any exposure, providing the safety data sheet for proper medical treatment.

Oxolan-2-ylmethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate must be disposed of as hazardous waste through licensed waste management companies due to its carcinogenic and environmentally hazardous classification. The compound cannot be discharged to sewers or general waste streams. Disposal must comply with local, national, and EU waste regulations including the Waste Framework Directive. Containers should be triple-rinsed and treated as contaminated waste. Incineration at appropriate high-temperature hazardous waste facilities is typically the preferred disposal method for such organic compounds.

Oxolan-2-ylmethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate is classified as ADR Class 9 (miscellaneous dangerous goods), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to ADR regulations for road transport in Europe. Packages must display proper hazard labels and shipping names. Transport vehicles require appropriate placarding and drivers need ADR certification. The compound must be packaged in UN-approved containers with proper cushioning and leak-proof secondary containment to prevent environmental release during transport.

Oxolan-2-ylmethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate is subject to comprehensive EU chemical regulations including REACH registration requirements and CLP classification obligations. While not currently listed as a Substance of Very High Concern (SVHC), its carcinogenic and reproductive toxicity classification requires strict compliance with occupational exposure limits and worker protection measures. The substance falls under hazardous chemicals legislation requiring proper risk assessment, safety data sheets, and notification procedures. Import and use may require specific authorizations depending on intended applications and quantities involved.

Oxolan-2-ylmethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate is available through OYSI, a specialized European distributor of technical chemicals serving industrial and research customers across Europe. OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance support required for hazardous chemical distribution. As a professional chemical supplier, OYSI ensures appropriate packaging, labeling, and transport arrangements meeting all European regulatory requirements. Contact OYSI directly for availability, specifications, and procurement of this specialized chemical compound for your specific industrial or research applications.