N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide

N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide is a complex heterocyclic organic compound with the molecular formula C14H13F3N6O5S and CAS number 422556-08-9. This sulfonamide derivative features both triazolopyrimidine and pyridine ring systems, with a molecular weight of 434.35 g/mol. The compound contains multiple functional groups including methoxy, trifluoromethyl, and sulfonamide moieties, making it structurally complex and potentially bioactive.

This compound has a molecular weight of 434.35 g/mol and molecular formula C14H13F3N6O5S. The presence of trifluoromethyl groups typically imparts lipophilic character, while the sulfonamide and methoxy groups contribute to polar interactions. The multiple nitrogen-containing heterocycles suggest potential for hydrogen bonding. The exact physical state, color, odor, and solubility data would need to be determined experimentally or sourced from detailed technical specifications, as these properties are not standardly reported for this specialized compound.

This compound is primarily used in pharmaceutical research and development applications. The triazolopyrimidine-pyridine sulfonamide structure suggests potential use as a pharmaceutical intermediate or active pharmaceutical ingredient (API). Such complex heterocyclic compounds are often employed in medicinal chemistry for drug discovery programs, particularly in developing treatments where specific molecular interactions are required. The compound may also serve research purposes in academic and industrial laboratories studying bioactive molecules or synthetic methodology development.

This compound requires careful handling due to its Skin Sens. 1 classification, indicating it may cause allergic skin reactions. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid direct skin and eye contact. Use proper handling techniques to prevent dust generation and cross-contamination. Ensure personnel are trained in chemical safety protocols and have access to safety data sheets before handling.

Store this compound in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly sealed to prevent moisture absorption and contamination. Due to its aquatic toxicity classification, ensure storage areas have appropriate containment measures to prevent environmental release. Store away from incompatible materials and oxidizing agents. Maintain proper inventory controls and labeling according to GHS requirements. Regular inspection of storage containers and conditions is recommended to ensure product integrity and safety compliance.

In case of skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for at least 15 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Given the skin sensitization potential, monitor for allergic reactions and seek medical advice if symptoms develop. Always consult the safety data sheet for complete first aid procedures.

This compound requires special disposal consideration due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications, indicating high environmental toxicity. Dispose of through licensed hazardous waste disposal companies in accordance with local, national, and EU regulations. Never discharge to sewers, waterways, or soil. Contaminated packaging should also be treated as hazardous waste. Maintain proper documentation of disposal activities. Consider waste minimization strategies and recycling options where technically and economically feasible, following pharmaceutical waste management guidelines.

This compound is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III, indicating it presents relatively lower transport risk. Packaging must comply with UN packaging requirements for Class 9 substances. Proper shipping documentation including dangerous goods declarations must accompany shipments. Vehicles and personnel involved in transport must meet ADR certification requirements. Ensure packages are properly labeled with appropriate hazard markings and emergency contact information. Follow specific routing and handling requirements for Class 9 dangerous goods during European transport.

This compound is subject to EU REACH regulation requiring registration, evaluation, and authorization for commercial use. It must be classified and labeled according to CLP regulation, displaying GHS07 and GHS09 pictograms with Warning signal word. While not currently identified as a Substance of Very High Concern (SVHC), it requires compliance with standard chemical safety requirements. Users must maintain safety data sheets, conduct risk assessments, and implement appropriate risk management measures. Pharmaceutical applications may require additional regulatory compliance depending on intended use.

OYSI is a reliable European distributor for this specialized compound, offering professional chemical supply services across Europe. As a specialized pharmaceutical intermediate, this compound is typically available through established chemical distributors serving research institutions and pharmaceutical companies. OYSI provides comprehensive technical support, regulatory documentation, and quality assurance for chemical products. Contact OYSI directly for availability, specifications, and pricing information. Ensure your supplier provides complete documentation including certificates of analysis and safety data sheets for regulatory compliance.