N'-(4-nitrosophenyl)benzohydrazide

C13H11N3O2

CAS495-73-8
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
495-73-8
EC Number
207-807-9
UN Number
2588
Index Number
650-006-00-8
PubChem CID
10320

Physical-chemical properties

Molecular Formula
C13H11N3O2
Molar Mass
241.24 g/mol
IUPAC Name
N'-(4-nitrosophenyl)benzohydrazide

Chemical Identifiers

InChI
InChI=1S/C13H11N3O2/c17-13(10-4-2-1-3-5-10)15-14-11-6-8-12(16-18)9-7-11/h1-9,14H,(H,15,17)
InChI Key
ORLIFVYIUIQGOA-UHFFFAOYSA-N

Overview

N'-(4-nitrosophenyl)benzohydrazide (CAS 495-73-8) is an organic hydrazide compound with nitroso functionality and acute toxicity properties. This specialized chemical compound represents a significant class of nitroso-substituted hydrazides used in various industrial applications. With its molecular formula C13H11N3O2 and molecular weight of 241.24 g/mol, N'-(4-nitrosophenyl)benzohydrazide exhibits distinctive chemical characteristics due to the presence of both benzohydrazide and nitrosophenyl functional groups. The compound's structure features a benzoyl group linked to a hydrazine moiety, which is further substituted with a 4-nitrosophenyl group, creating unique reactivity patterns essential for specific chemical processes. From a safety perspective, this substance is classified under Acute Toxicity categories 3 and 4, requiring careful handling protocols. The GHS06 pictogram and "Danger" signal word indicate significant health hazards, while its ADR classification 6.1 designates it as a toxic substance for transport purposes. These safety considerations make proper storage, handling, and disposal critical for industrial users. Industrial applications typically include use as a chemical intermediate in pharmaceutical synthesis, specialized analytical reagents, and research applications requiring nitroso compounds. Unlike simpler compounds such as barium(2+) dichloride, this hydrazide derivative offers specific reactivity patterns valuable in organic synthesis. The compound's unique structure makes it particularly useful in developing specialized chemical processes where both hydrazide and nitroso functionalities are required. OYSI maintains availability of N'-(4-nitrosophenyl)benzohydrazide for qualified industrial customers across Europe, ensuring consistent supply for technical applications requiring this specialized chemical intermediate.

Safety & Classification

Danger
Classification:

Acute Tox. 4 *; Acute Tox. 3 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H312

Harmful in contact with skin.

H301

Toxic if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2588
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameBenquinox (ISO)
Marine PollutantNo

Frequently Asked Questions

What is N'-(4-nitrosophenyl)benzohydrazide?

N'-(4-nitrosophenyl)benzohydrazide is an organic chemical compound with the molecular formula C13H11N3O2 and CAS number 495-73-8. This substance has a molecular weight of 241.24 g/mol and belongs to the hydrazide family of compounds. It contains both nitroso and hydrazide functional groups, making it a specialized chemical intermediate. The compound is classified as hazardous with acute toxicity properties and requires careful handling in professional environments.

What are the physicochemical properties of N'-(4-nitrosophenyl)benzohydrazide?

N'-(4-nitrosophenyl)benzohydrazide is a solid organic compound with a molecular weight of 241.24 g/mol and the formula C13H11N3O2. As a nitroso-containing aromatic compound, it typically appears as a colored solid due to the presence of the nitroso group. The compound contains both hydrophilic (hydrazide) and hydrophobic (aromatic) regions, affecting its solubility properties. Specific physical parameters like melting point and solubility data should be confirmed through technical documentation.

What is N'-(4-nitrosophenyl)benzohydrazide used for?

N'-(4-nitrosophenyl)benzohydrazide serves primarily as a chemical intermediate in organic synthesis and pharmaceutical research. The compound's unique structure, combining nitroso and hydrazide functionalities, makes it valuable for developing specialized organic molecules. It may be used in the synthesis of more complex pharmaceutical compounds or as a reagent in analytical chemistry. Its applications are typically limited to professional laboratory and industrial settings due to its hazardous classification.

How to handle N'-(4-nitrosophenyl)benzohydrazide safely?

N'-(4-nitrosophenyl)benzohydrazide requires careful handling due to its Acute Tox. 4 and Acute Tox. 3 classifications with GHS06 pictogram. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin contact and ingestion. Emergency procedures should be readily available, and personnel must be trained in proper handling techniques before working with this hazardous substance.

How to store N'-(4-nitrosophenyl)benzohydrazide correctly?

N'-(4-nitrosophenyl)benzohydrazide should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly closed and properly labeled according to GHS requirements. Storage areas must be secure and accessible only to trained personnel due to the compound's acute toxicity classification. Avoid exposure to heat, light, and moisture which may affect stability. Implement appropriate containment measures to prevent accidental release and ensure compliance with local hazardous material storage regulations.

What to do in case of contact with N'-(4-nitrosophenyl)benzohydrazide?

Immediate action is required in case of contact with N'-(4-nitrosophenyl)benzohydrazide due to its acute toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for specific first aid measures and contact poison control if necessary.

How to dispose of N'-(4-nitrosophenyl)benzohydrazide properly?

N'-(4-nitrosophenyl)benzohydrazide must be disposed of through licensed hazardous waste management facilities due to its acute toxicity classification. The compound cannot be disposed of in regular waste streams or sewage systems. Collect waste in appropriate, labeled containers and arrange disposal through certified waste management companies. Follow local and national regulations for hazardous waste disposal, including proper documentation and manifest requirements. Never attempt to neutralize or treat this substance without proper authorization and expertise.

How to transport N'-(4-nitrosophenyl)benzohydrazide?

N'-(4-nitrosophenyl)benzohydrazide is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Shipments must use UN-approved packaging with appropriate hazard labels and safety markings. Transport vehicles require proper placarding and drivers need hazardous materials certification. All transport documentation must comply with ADR requirements for Class 6.1 substances, ensuring safe handling throughout the logistics chain.

Is N'-(4-nitrosophenyl)benzohydrazide subject to specific regulations?

N'-(4-nitrosophenyl)benzohydrazide is subject to various chemical safety regulations including REACH registration requirements in Europe and CLP classification for hazard communication. The compound is classified under acute toxicity categories requiring specific labeling with GHS06 pictogram and 'Danger' signal word. While not currently listed as a SVHC substance, it remains subject to standard chemical safety assessments. Users must comply with occupational safety regulations, transport classification ADR 6.1, and maintain appropriate safety data sheets for workplace safety.

Where to buy N'-(4-nitrosophenyl)benzohydrazide in Europe?

N'-(4-nitrosophenyl)benzohydrazide is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to qualified industrial and research customers with proper handling capabilities for hazardous materials. Due to the substance's acute toxicity classification, purchases are restricted to professional users with appropriate safety infrastructure and trained personnel. Contact OYSI directly for availability, technical specifications, and regulatory compliance documentation required for safe procurement and use of this specialized chemical compound.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.