N'-(4-nitrosophenyl)benzohydrazide

C13H11N3O2

CAS495-73-8
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
495-73-8
EC Number
207-807-9
UN Number
2588
Index Number
650-006-00-8
PubChem CID
10320

Physical-chemical properties

Molecular Formula
C13H11N3O2
Molar Mass
241.24 g/mol
IUPAC Name
N'-(4-nitrosophenyl)benzohydrazide

Chemical Identifiers

InChI
InChI=1S/C13H11N3O2/c17-13(10-4-2-1-3-5-10)15-14-11-6-8-12(16-18)9-7-11/h1-9,14H,(H,15,17)
InChI Key
ORLIFVYIUIQGOA-UHFFFAOYSA-N

Overview

N'-(4-nitrosophenyl)benzohydrazide (CAS 495-73-8) is an organic hydrazide compound characterized by its nitroso-substituted aromatic structure and acute toxicity properties. This specialized chemical compound belongs to the hydrazide family, featuring a distinctive molecular structure that combines a benzohydrazide moiety with a 4-nitrosophenyl group. With the molecular formula C13H11N3O2 and a molecular weight of 241.24 g/mol, this substance exhibits unique chemical properties that make it valuable in specific industrial applications. The compound's structure incorporates both nitroso and hydrazide functional groups, which contribute to its reactivity profile and chemical behavior. From a safety perspective, N'-(4-nitrosophenyl)benzohydrazide requires careful handling due to its classification under Acute Tox. 4 and Acute Tox. 3 categories. The substance displays the GHS06 pictogram and carries a "Danger" signal word, indicating significant toxicity concerns. For transportation purposes, it falls under ADR Class 6.1, reflecting its toxic nature. These safety classifications necessitate appropriate protective equipment and controlled handling procedures in industrial settings. The compound finds application in analytical chemistry as a reagent, particularly in spectrophotometric analysis and chemical synthesis processes. It serves as an intermediate in organic synthesis reactions and can be utilized in research applications involving nitroso chemistry. Unlike simpler compounds such as barium(2+) dichloride, this hydrazide derivative offers more specialized functionality in targeted chemical processes. Industrial users often employ N'-(4-nitrosophenyl)benzohydrazide in pharmaceutical intermediate synthesis and specialty chemical manufacturing. Its unique structural features make it suitable for developing specific chemical products where the combination of hydrazide and nitroso functionalities is required. OYSI provides reliable access to N'-(4-nitrosophenyl)benzohydrazide for European industrial customers requiring this specialized chemical compound.

Safety & Classification

Danger
Classification:

Acute Tox. 4 *; Acute Tox. 3 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H312

Harmful in contact with skin.

H301

Toxic if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2588
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameBenquinox (ISO)
Marine PollutantNo

Frequently Asked Questions

What is N'-(4-nitrosophenyl)benzohydrazide?

N'-(4-nitrosophenyl)benzohydrazide is an organic chemical compound with the molecular formula C13H11N3O2 and CAS number 495-73-8. This benzohydrazide derivative contains a nitroso functional group attached to a phenyl ring, which is connected to a benzohydrazide moiety. With a molecular weight of 241.24 g/mol, it belongs to the class of aromatic hydrazides and exhibits toxic properties requiring careful handling and safety precautions during use.

What are the physicochemical properties of N'-(4-nitrosophenyl)benzohydrazide?

N'-(4-nitrosophenyl)benzohydrazide is a solid organic compound at room temperature with the molecular formula C13H11N3O2. The compound typically appears as a crystalline powder, though specific physical properties like melting point, boiling point, and solubility data may vary depending on purity and crystalline form. Its aromatic structure with both hydrazide and nitroso functional groups influences its chemical reactivity and stability under different environmental conditions.

What is N'-(4-nitrosophenyl)benzohydrazide used for?

N'-(4-nitrosophenyl)benzohydrazide is primarily used as a chemical intermediate in organic synthesis and pharmaceutical research. The compound serves as a building block for the preparation of more complex molecules, particularly in medicinal chemistry applications. Its hydrazide functionality makes it valuable for forming various derivatives through condensation reactions, while the nitroso group provides additional reactive sites for chemical modifications in specialized synthesis processes.

How to handle N'-(4-nitrosophenyl)benzohydrazide safely?

N'-(4-nitrosophenyl)benzohydrazide must be handled with extreme caution due to its Acute Tox. 4 and Acute Tox. 3 classifications. Essential safety measures include wearing appropriate personal protective equipment such as chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid contact with skin, eyes, and mucous membranes, and ensure proper training before handling this hazardous substance.

How to store N'-(4-nitrosophenyl)benzohydrazide correctly?

N'-(4-nitrosophenyl)benzohydrazide should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and incompatible materials. Due to its toxic nature, storage must comply with local regulations for hazardous chemicals. Keep containers properly labeled and segregated from food, feed, and living areas. Regular inspection of storage conditions and container integrity is essential to prevent accidental exposure or environmental contamination.

What to do in case of contact with N'-(4-nitrosophenyl)benzohydrazide?

Immediate action is required in case of contact with N'-(4-nitrosophenyl)benzohydrazide due to its toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult emergency services for serious exposures.

How to dispose of N'-(4-nitrosophenyl)benzohydrazide appropriately?

N'-(4-nitrosophenyl)benzohydrazide must be disposed of as hazardous waste according to local and national environmental regulations. The compound cannot be disposed of through regular waste streams due to its toxic properties. Contact licensed hazardous waste disposal companies for proper collection and treatment. Ensure proper documentation of waste disposal activities and maintain records as required by regulatory authorities. Never discharge into sewers, water bodies, or soil.

How to transport N'-(4-nitrosophenyl)benzohydrazide?

N'-(4-nitrosophenyl)benzohydrazide is classified under ADR Class 6.1 (Toxic substances) Packing Group III for transportation. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Packages must bear appropriate hazard labels and markings, and transport vehicles must comply with ADR requirements. Only trained personnel should handle the transportation process, and proper emergency response information must accompany shipments throughout the transport chain.

Is N'-(4-nitrosophenyl)benzohydrazide subject to specific regulations?

N'-(4-nitrosophenyl)benzohydrazide is subject to various chemical safety regulations including REACH registration requirements for substances manufactured or imported in the European Union above certain tonnages. The compound must be classified and labeled according to CLP regulation due to its toxic properties. While not currently listed as a Substance of Very High Concern (SVHC), users must comply with occupational safety regulations and maintain safety data sheets for workplace safety compliance.

Where to buy N'-(4-nitrosophenyl)benzohydrazide in Europe?

N'-(4-nitrosophenyl)benzohydrazide is available through OYSI, a trusted European distributor of specialty chemicals and intermediates. OYSI provides reliable supply chains for laboratory and industrial customers across Europe, ensuring proper handling, packaging, and regulatory compliance. As a specialized chemical requiring careful handling due to its toxic properties, purchase should only be made by qualified professionals with appropriate facilities and safety measures for handling hazardous substances.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.