Methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate

Methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate is a complex organic chemical compound with CAS number 100784-20-1 and molecular formula C13H15ClN6O7S. This substance has a molecular weight of 434.81 g/mol and contains multiple functional groups including pyrazole, pyrimidine, and sulfamoyl moieties. It is classified as a reproductive toxicant and aquatic hazard, requiring careful handling in professional applications.

Methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate is a solid organic compound at room temperature with a molecular weight of 434.81 g/mol. The presence of multiple polar functional groups including methoxy, carbamoyl, and sulfamoyl groups suggests moderate to good solubility in polar solvents. The compound contains both aromatic and aliphatic components, with chlorine substitution affecting its chemical reactivity and stability properties.

Methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate is primarily used as a chemical intermediate in pharmaceutical and agrochemical synthesis. Its complex structure containing pyrimidine and pyrazole rings makes it valuable for developing specialized compounds. The substance may serve as a building block for manufacturing active pharmaceutical ingredients or advanced chemical products requiring specific molecular functionalities in research and industrial applications.

Methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate requires strict safety measures due to its reproductive toxicity classification (Repr. 1B). Mandatory personal protective equipment includes respiratory protection, chemical-resistant gloves, safety goggles, and protective clothing. Work must be conducted in well-ventilated areas or under fume extraction. Avoid skin contact, inhalation, and ingestion. Pregnant workers should not handle this substance due to reproductive hazards.

Methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Storage areas must be restricted to authorized personnel due to reproductive toxicity hazards. Keep away from incompatible materials and ensure proper labeling with GHS08 and GHS09 pictograms. Implement appropriate spill containment measures to prevent environmental contamination.

Immediate medical attention is required for any contact with methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate due to its reproductive toxicity. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately. In case of eye contact, flush with clean water for 15 minutes. Seek immediate medical advice and show the safety data sheet to medical personnel.

Methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate must be disposed of as hazardous waste through authorized waste management companies due to its reproductive toxicity and aquatic hazard classifications. Never dispose of this substance in regular waste streams or release into the environment. Waste containers must be properly labeled and documentation maintained. Follow local and national regulations for hazardous waste disposal, including proper waste classification codes.

Methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III. Transport requires proper UN specification packaging with appropriate hazard labels and documentation. Vehicles must carry emergency response information and drivers need ADR certification. Packages must display the correct shipping name, UN number, and hazard pictograms while ensuring secure loading to prevent damage during transit.

Methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate is subject to strict European CLP regulation due to its reproductive toxicity (Repr. 1B) and aquatic hazard classifications. While not currently listed as an SVHC under REACH, it requires comprehensive safety data sheets, proper hazard communication, and restricted access. Companies must implement risk management measures and may need authorization for certain uses under occupational health regulations.

Methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this substance to qualified industrial and research customers with proper documentation and regulatory compliance. Due to its hazardous classification, purchase requires verification of intended use and appropriate handling capabilities. Contact OYSI directly for availability, technical specifications, and regulatory documentation for your specific application requirements.