(4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane

C25H29FO2Si

CAS105024-66-6
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
105024-66-6
EC Number
405-020-7
UN Number
3082
Index Number
014-036-00-X
PubChem CID
92430

Physical-chemical properties

Molecular Formula
C25H29FO2Si
Molar Mass
408.60 g/mol
IUPAC Name
(4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane

Chemical Identifiers

InChI
InChI=1S/C25H29FO2Si/c1-4-27-21-13-15-23(16-14-21)29(2,3)18-8-9-20-12-17-24(26)25(19-20)28-22-10-6-5-7-11-22/h5-7,10-17,19H,4,8-9,18H2,1-3H3
InChI Key
HPYNBECUCCGGPA-UHFFFAOYSA-N

Overview

(4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane (CAS 105024-66-6) is an organosilicon compound with reproductive toxicity and aquatic environmental hazard properties. This specialized organosilicon compound represents a complex aromatic structure combining silane functionality with ethoxyphenyl and fluorinated phenoxyphenyl groups. The molecular formula C25H29FO2Si indicates a substantial organic framework with a molecular weight of 408.6 g/mol, incorporating fluorine substitution that often enhances chemical stability and biological activity in pharmaceutical intermediates. The compound's hazard classification as Repr. 1B indicates confirmed reproductive toxicity in laboratory studies, requiring stringent handling protocols and personal protective equipment. The Aquatic Acute 1 and Aquatic Chronic 1 classifications signal significant environmental concerns, necessitating careful waste management and environmental release prevention. The GHS08 and GHS09 pictograms emphasize both health hazards and environmental dangers, while the ADR Class 9 classification covers miscellaneous dangerous substances during transport. Safety considerations include proper ventilation systems, appropriate containment measures, and specialized disposal procedures due to the compound's environmental persistence. The organosilicon structure provides unique chemical properties that distinguish it from related compounds such as 2-benzyl-2-(dimethylamino)-1-(4-morpholin-4-ylphenyl)butan-1-one, which features different heterocyclic functionality. Industrial applications typically include pharmaceutical intermediate synthesis, specialty polymer modification, and advanced materials development where fluorinated aromatic silanes provide specific performance characteristics. The compound may also serve in surface treatment applications requiring both organic compatibility and silicone functionality. OYSI maintains availability of this specialized organosilicon compound for qualified industrial customers requiring high-purity chemical intermediates.

Safety & Classification

Danger
Classification:

Repr. 1B; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Transport (ADR)

UN Number3082
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameSilafluofen
Marine PollutantNo

Frequently Asked Questions

What is (4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane?

(4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane is an organosilicon compound with the molecular formula C25H29FO2Si and CAS number 105024-66-6. This complex aromatic silane derivative has a molecular weight of 408.6 g/mol and contains ethoxy, fluoro, and phenoxy functional groups. It is classified as a reproductive toxicant (Category 1B) and poses acute and chronic aquatic hazards, requiring careful handling procedures.

What are the physicochemical properties of (4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane?

(4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane is an organosilicon compound with a molecular weight of 408.6 g/mol. As a complex aromatic silane, it likely exists as a liquid at room temperature due to its molecular structure and weight. The presence of multiple aromatic rings and functional groups suggests limited water solubility but good solubility in organic solvents. Specific physical properties should be confirmed through technical documentation.

What is (4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane used for?

(4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane is primarily used as a specialty chemical intermediate in pharmaceutical and fine chemical synthesis. Its organosilicon structure makes it valuable for advanced material applications, including surface modification and as a building block for silicon-containing compounds. The compound may also find applications in research and development of new materials or as a coupling agent in specialized formulations.

How to handle (4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane safely?

(4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane must be handled with extreme caution due to its reproductive toxicity (Category 1B). Workers must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Pregnant women should not handle this substance due to reproductive hazards.

How to store (4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane correctly?

(4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly sealed and protected from light and moisture. Due to its reproductive toxicity and environmental hazards, storage areas must be restricted to authorized personnel only. Secondary containment is recommended to prevent environmental release. Maintain proper labeling and safety documentation in storage areas.

What to do in case of contact with (4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane?

Immediate action is required upon contact with (4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane due to its reproductive toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with clean water for at least 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention promptly for any exposure, informing healthcare providers of the substance's reproductive hazards.

How to dispose of (4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane appropriately?

(4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane must be disposed of as hazardous waste due to its reproductive toxicity and environmental hazards (Aquatic Acute 1, Aquatic Chronic 1). Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never dispose of down drains or in regular waste. Follow local and national regulations for hazardous waste management. Maintain disposal records for regulatory compliance and environmental protection.

How to transport (4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane?

(4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Transporters must be properly trained and vehicles appropriately equipped. Shipping documents must include proper shipping names, hazard classes, and emergency contact information. Ensure compliance with international transport regulations.

Is (4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane subject to specific regulations?

(4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane is subject to comprehensive chemical regulations including REACH registration requirements in Europe and CLP classification as a reproductive toxicant Category 1B. While not currently listed as a SVHC, its reproductive toxicity classification subjects it to strict handling, labeling, and safety data sheet requirements. Companies must ensure proper risk assessments, worker protection measures, and regulatory compliance throughout the supply chain.

Where to buy (4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane in Europe?

(4-ethoxyphenyl)-[3-(4-fluoro-3-phenoxyphenyl)propyl]-dimethylsilane is available through specialized chemical distributors in Europe, including OYSI, a leading European distributor of technical chemicals. Due to its hazardous classification and specialized nature, this compound requires proper regulatory documentation and handling expertise. Professional buyers should contact established chemical suppliers who can ensure proper packaging, documentation, and compliance with European chemical regulations for safe procurement and delivery.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.