Methyl (2R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate

Methyl (2R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate is an organic chemical compound with CAS number 72619-32-0 and molecular formula C16H13ClF3NO4. This complex molecule has a molecular weight of 375.72 g/mol and features a chiral center, indicated by the (2R) stereochemical designation. The compound contains chlorine, fluorine, nitrogen, and oxygen functional groups within its pyridine-based structure, making it a highly specialized chemical intermediate.

Methyl (2R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate is a solid compound at room temperature with a molecular weight of 375.72 g/mol. The presence of trifluoromethyl groups typically confers high chemical stability and low volatility. The compound's solubility characteristics are influenced by both its aromatic rings and polar functional groups. Its complex structure with multiple heteroatoms suggests moderate polarity, though specific solubility data should be confirmed through technical documentation.

Methyl (2R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate is primarily used as a chemical intermediate in pharmaceutical and agrochemical synthesis. Its complex structure with pyridine rings and chiral center makes it valuable for developing biologically active compounds. The compound serves as a building block in organic synthesis, particularly in the production of specialized pharmaceuticals or crop protection agents. Its specific stereochemistry (2R configuration) is crucial for creating enantiomerically pure final products.

Methyl (2R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate requires careful handling due to its Acute Tox. 4 classification. Use appropriate personal protective equipment including safety goggles, gloves, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation. The Warning signal word indicates moderate hazard level, but proper precautions are essential. Avoid direct skin and eye contact, and prevent ingestion. Follow good laboratory practices and consult the safety data sheet for specific handling procedures.

Methyl (2R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed to prevent moisture absorption and contamination. Store away from incompatible materials and oxidizing agents. Given its aquatic toxicity classification, ensure proper containment to prevent environmental release. Use appropriate secondary containment and maintain proper inventory records. Store in original labeled containers and check regularly for signs of degradation or container damage.

In case of skin contact with methyl (2R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate, immediately remove contaminated clothing and wash thoroughly with soap and water. For eye contact, flush immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Given its Acute Tox. 4 classification, prompt medical evaluation is recommended for any significant exposure. Keep safety data sheet available for emergency responders.

Methyl (2R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate must be disposed of according to local and national hazardous waste regulations due to its toxicity and environmental hazard classifications. The compound requires specialized treatment due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications, indicating high aquatic toxicity. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never discharge to sewers, waterways, or soil. Contaminated packaging should also be treated as hazardous waste and disposed of accordingly through approved channels.

Methyl (2R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to ADR regulations. Use UN-approved packaging suitable for Packing Group III materials. Proper shipping names, hazard labels, and transport documents must accompany shipments. Vehicle drivers require ADR training for Class 9 materials. Ensure packages are properly secured and protected from damage during transport to prevent environmental release.

Methyl (2R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate is subject to standard REACH registration and CLP classification requirements in Europe, though it is not currently listed as a Substance of Very High Concern (SVHC). The compound must comply with hazard classification requirements under CLP regulation, displaying appropriate GHS07 and GHS09 pictograms. Its acute toxicity and aquatic toxicity classifications may trigger additional reporting requirements for industrial use. Users must maintain safety data sheets and follow worker protection regulations based on its hazard profile.

Methyl (2R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to pharmaceutical, agrochemical, and research organizations across Europe with proper documentation and regulatory compliance. As a specialized chemical intermediate, availability may be subject to minimum order quantities and lead times. Contact OYSI directly for current availability, specifications, pricing, and delivery options. Ensure your intended use complies with all applicable regulations before ordering this controlled substance.