Methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate

C18H19NO4

methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate

CAS143390-89-0
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
143390-89-0
UN Number
3077
Index Number
607-310-00-0
PubChem CID
6112114

Physical-chemical properties

Molecular Formula
C18H19NO4
Molar Mass
313.30 g/mol
IUPAC Name
methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate

Chemical Identifiers

InChI
InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+
InChI Key
ZOTBXTZVPHCKPN-HTXNQAPBSA-N

Overview

Methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate (CAS 143390-89-0) is an organic compound with molecular formula C18H19NO4 featuring methoxyimino and phenoxy functional groups. This synthetic organic compound belongs to the class of substituted acetate esters and represents a complex aromatic molecule with multiple functional groups that contribute to its specific chemical properties. With a molecular weight of 313.3 g/mol, this substance exhibits structural characteristics typical of advanced organic intermediates used in specialized industrial applications. The compound's molecular structure incorporates several key functional elements: a methoxyimino group (-C=N-OCH3), a substituted phenyl ring system, and a methyl acetate moiety. The (2E) designation indicates the geometric configuration around the C=N double bond, which is crucial for its biological and chemical activity. The presence of the 2-methylphenoxy group attached via a methylene bridge adds to the molecule's structural complexity and influences its physical and chemical properties. From a safety perspective, this compound requires careful handling due to its classification as a Category 2 carcinogen and its acute and chronic aquatic toxicity (Aquatic Acute 1, Aquatic Chronic 1). The warning signal word and associated GHS08 and GHS09 pictograms indicate potential health hazards and environmental risks. As a Class 9 ADR substance, it falls under miscellaneous dangerous goods for transportation purposes. Industrial applications typically include use as a chemical intermediate in pharmaceutical synthesis, agrochemical production, and specialty chemical manufacturing. Like related compounds such as 4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine, it may serve in the development of bioactive molecules requiring precise structural modifications. OYSI provides this specialized chemical compound to meet the demanding requirements of European industrial customers in pharmaceutical and chemical manufacturing sectors.

Safety & Classification

Warning
Classification:

Carc. 2; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameKresoxim-methyl (ISO)
Marine PollutantNo

Frequently Asked Questions

What is methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate?

Methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate is an organic chemical compound with the molecular formula C18H19NO4 and CAS number 143390-89-0. This substance has a molecular weight of 313.3 g/mol and belongs to the class of methoxyimino acetate derivatives. It is classified as a Category 2 carcinogen and poses significant environmental hazards to aquatic life, requiring careful handling and regulatory compliance in industrial applications.

What are the physicochemical properties of methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate?

Methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate is a complex organic ester with a molecular weight of 313.3 g/mol and molecular formula C18H19NO4. The compound features methoxyimino and phenoxy functional groups, which influence its chemical reactivity and solubility characteristics. Its exact physical properties such as melting point, boiling point, and solubility data require laboratory analysis for specific applications and handling procedures.

What is methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate used for?

Methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate is typically used as an intermediate in pharmaceutical and agrochemical synthesis. The compound's methoxyimino acetate structure makes it valuable in the production of specialized organic compounds and active pharmaceutical ingredients. Its specific applications depend on the target molecules being synthesized, often serving as a building block in multi-step organic synthesis processes within controlled industrial environments.

How to safely handle methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate?

Methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate requires strict safety protocols due to its Category 2 carcinogen classification. Personnel must wear appropriate PPE including gloves, safety goggles, and respiratory protection when handling this substance. Work should be conducted in well-ventilated areas or under fume hoods to minimize exposure. The GHS08 health hazard pictogram indicates serious health risks, making proper training and safety procedures essential for all personnel.

How to properly store methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate?

Methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate must be stored in a secure, well-ventilated area away from heat sources and incompatible materials. Due to its carcinogenic properties and environmental hazards, storage requires appropriate containment measures to prevent accidental release. The storage area should be clearly labeled with appropriate hazard warnings and access should be restricted to trained personnel only, following all local and international safety regulations.

What to do in case of contact with methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate?

Immediate action is required if contact occurs with methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with water for at least 15 minutes. Seek immediate medical attention in all cases, informing healthcare providers of the substance's carcinogenic properties and providing the safety data sheet.

How to properly dispose of methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate?

Methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate must be disposed of through licensed hazardous waste facilities due to its carcinogenic and environmental hazard classifications. The substance cannot be discharged into sewers or the environment due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Disposal must comply with local, national, and European waste regulations, typically requiring incineration at high temperatures in specialized facilities equipped for hazardous chemical waste treatment.

How to transport methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate?

Methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation during transport. Shipments must comply with international dangerous goods regulations and be handled by qualified carriers familiar with hazardous material transportation requirements. Proper emergency response information must accompany all shipments.

Is methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate subject to specific regulations?

Methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate is subject to strict European regulations under REACH and CLP due to its hazardous properties. The substance requires appropriate classification, labeling, and safety data sheets displaying GHS08 and GHS09 pictograms with 'Warning' signal word. While not currently listed as an SVHC, its carcinogenic classification means it may be subject to additional restrictions and authorization requirements depending on intended use and exposure scenarios.

Where to buy methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate in Europe?

Methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate is available through OYSI, a specialized European distributor of technical chemicals. As this substance requires expert handling due to its hazardous classification, OYSI provides comprehensive technical support, proper documentation, and regulatory compliance assistance. Professional buyers can contact OYSI directly to discuss specific requirements, quantities, and delivery arrangements while ensuring full compliance with European chemical regulations and safety standards.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.