4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine is an organic chemical compound with the molecular formula C14H13N3 and CAS number 110235-47-7. This pyrimidine derivative has a molecular weight of 223.27 g/mol and features a complex structure containing pyrimidine, phenyl, and propynyl functional groups. It is classified as a potential carcinogen (Category 2) and poses environmental hazards to aquatic life, requiring careful handling and regulatory compliance.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine is a solid organic compound at room temperature with a molecular weight of 223.27 g/mol. The compound contains aromatic rings and nitrogen heteroatoms, suggesting limited water solubility but good solubility in organic solvents. Its pyrimidine-based structure with phenyl and alkyne substituents contributes to its stability under normal conditions. Specific physical properties like melting point, boiling point, and exact solubility data would require analytical characterization.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine is primarily used as a research chemical and pharmaceutical intermediate in organic synthesis. Its pyrimidine structure makes it valuable for developing pharmaceutical compounds, particularly in medicinal chemistry research. The compound may also serve as a building block for agrochemicals or specialty chemicals. Given its hazard classification, applications are typically limited to professional and industrial settings with appropriate safety controls and regulatory oversight.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine requires careful handling due to its suspected carcinogenic properties. Use appropriate personal protective equipment including nitrile gloves, safety goggles, and lab coats. Work in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin contact, ingestion, and dust generation. Implement strict hygiene measures including hand washing after handling. Follow your organization's chemical safety protocols and ensure all personnel are trained on the specific hazards associated with this Category 2 carcinogen.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly closed and properly labeled with hazard warnings. Store in a designated area for carcinogenic substances with restricted access. Maintain storage temperature below 25°C and protect from moisture and light. Ensure storage areas have appropriate spill containment measures and are separate from food, feed, and oxidizing agents to prevent contamination or hazardous reactions.

Immediate action is required upon contact with 4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with clean water for 15 minutes while holding eyelids open. If ingested, do not induce vomiting and rinse mouth with water. Seek immediate medical attention in all cases and provide the safety data sheet to medical personnel.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine must be disposed of as hazardous waste due to its carcinogenic and environmental hazard classifications. Never dispose of in regular waste streams, drains, or the environment. Contact a licensed hazardous waste disposal company for proper treatment and disposal. Maintain detailed waste tracking records as required by local regulations. Empty containers should also be treated as hazardous waste. Follow all applicable national, regional, and local environmental regulations for hazardous chemical disposal.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation for road transport. Packages must bear proper shipping names, UN numbers, and hazard labels. Transport vehicles should carry appropriate emergency equipment and drivers must have ADR training. Ensure packages are secure, properly sealed, and accompanied by transport documents including safety data sheets and emergency response information.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine is subject to multiple regulatory frameworks including REACH registration requirements for import/manufacture in the EU and CLP classification for hazard communication. As a suspected carcinogen, it requires special workplace safety measures and may be subject to occupational exposure limits. While not currently listed as an SVHC, its hazard profile means it could face future regulatory restrictions. Companies must maintain safety data sheets, implement risk management measures, and comply with chemical inventory reporting requirements.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this research chemical to qualified industrial and academic customers across Europe with full regulatory compliance and proper documentation. As a controlled substance due to its hazard classification, purchases require verification of legitimate use and appropriate safety capabilities. Contact OYSI directly for availability, specifications, and regulatory documentation to ensure compliant procurement for your research or industrial applications.