4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine is a synthetic organic compound with the molecular formula C14H13N3 and CAS number 110235-47-7. This pyrimidine derivative has a molecular weight of 223.27 g/mol and contains an alkyne functional group. It is classified as a potentially carcinogenic substance (Carc. 2) and poses risks to aquatic environments (Aquatic Acute 1; Aquatic Chronic 1).

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine is an organic solid compound with a molecular formula C14H13N3 and molecular weight of 223.27 g/mol. The molecule contains aromatic pyrimidine and phenyl rings connected through an amine linkage, along with methyl and propynyl substituents. Specific physical properties such as melting point, boiling point, and solubility data would require analytical characterization.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine is primarily used as a research chemical and pharmaceutical intermediate. Its pyrimidine structure makes it valuable for medicinal chemistry applications, particularly in drug discovery and development programs. The compound may also serve as a building block for the synthesis of more complex organic molecules in specialized chemical manufacturing processes.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine requires careful handling due to its Carc. 2 classification. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid skin contact, ingestion, and inhalation. Ensure proper training on cancer hazard awareness before handling.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Due to its carcinogenic classification, implement restricted access controls and proper labeling. Store separately from oxidizing agents, acids, and bases. Maintain stable temperature conditions and protect from light and moisture to ensure product stability.

Immediate decontamination is essential following contact with 4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention, informing healthcare providers of the carcinogenic nature.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine must be disposed of as hazardous waste through licensed waste management companies due to its carcinogenic and aquatic toxicity properties. Never discharge to sewers, waterways, or regular trash. Follow local and national regulations for hazardous waste disposal. Incineration at authorized high-temperature facilities is typically the preferred disposal method. Maintain proper documentation of waste disposal activities.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transportation. This classification requires appropriate UN-specification packaging, proper labeling with GHS08 and GHS09 pictograms, and transport documentation. Vehicles must carry appropriate safety equipment and emergency response information. Drivers require ADR training for Class 9 substances and must follow routing restrictions where applicable.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine falls under REACH registration requirements in Europe and must comply with CLP regulation for classification and labeling as Carc. 2, Aquatic Acute 1, and Aquatic Chronic 1. While not currently listed as SVHC, its carcinogenic properties may trigger authorization requirements under certain uses. Users must implement appropriate risk management measures and maintain safety data sheets.

4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides reliable supply chain management for research chemicals and pharmaceutical intermediates across Europe. As a professional chemical distributor, OYSI ensures proper handling, documentation, and regulatory compliance for hazardous substances like this carcinogenic compound, supporting pharmaceutical and research applications.