Magnesium;carbanide;bromide
CH3BrMg
magnesium;carbanide;bromide
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Identification
- CAS Number
- 75-16-1
- EC Number
- 200-844-1
- UN Number
- 1928
- PubChem CID
- 6349
Physical-chemical properties
- Molecular Formula
- CH3BrMg
- Molar Mass
- 119.24 g/mol
- IUPAC Name
- magnesium;carbanide;bromide
Chemical Identifiers
- InChI
- InChI=1S/CH3.BrH.Mg/h1H3;1H;/q-1;;+2/p-1
- InChI Key
- NXPHGHWWQRMDIA-UHFFFAOYSA-M
Overview
Magnesium carbanide bromide (CAS 75-16-1) is an organometallic Grignard reagent with high reactivity toward carbonyl compounds and moisture sensitivity. This organometallic compound, also known by its molecular formula CH3BrMg, represents one of the most fundamental Grignard reagents used in synthetic organic chemistry. With a molecular weight of 119.24 g/mol, magnesium carbanide bromide serves as a crucial building block for carbon-carbon bond formation reactions. The compound consists of a magnesium center bonded to both a methyl carbanide group and a bromide ion, creating a highly nucleophilic species that readily attacks electrophilic carbon centers. The primary safety consideration for magnesium carbanide bromide stems from its extreme sensitivity to moisture and air, requiring handling under strictly anhydrous conditions and inert atmosphere protection. Its ADR classification as Class 4.3 indicates it reacts dangerously with water, potentially generating flammable gases. Unlike metallic reagents such as mercury or sodium, Grignard reagents like magnesium carbanide bromide offer more controlled reactivity while maintaining high synthetic utility. Storage requires absolute exclusion of moisture and oxygen, typically in dry ethereal solvents under nitrogen or argon atmosphere. In industrial applications, magnesium carbanide bromide finds extensive use in pharmaceutical intermediate synthesis, where it enables methylation reactions and carbon chain extension processes. The compound also serves as a key reagent in fine chemical manufacturing for producing alcohols, ketones, and carboxylic acids through controlled addition to various carbonyl substrates. Additionally, it plays a significant role in polymer chemistry for initiating certain polymerization reactions and creating functionalized polymer end groups. OYSI maintains reliable supplies of high-quality magnesium carbanide bromide to support European chemical manufacturing and research applications.
Safety & Classification
No Hazard Classification
This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.
Transport (ADR)
| UN Number | 1928 |
| ADR Class | 4.3 |
| Packing Group | I |
| Tunnel Code | B/E |
| Proper Shipping Name | Methylmagnesiumbromid in Ethylether |
| Marine Pollutant | No |
Frequently Asked Questions
What is magnesium;carbanide;bromide?
Magnesium;carbanide;bromide is an organometallic compound with the chemical formula CH3BrMg and CAS number 75-16-1. This compound belongs to the family of Grignard reagents, characterized by a carbon-magnesium bond. With a molecular weight of 119.24 g/mol, it represents a fundamental building block in organic synthesis, enabling the formation of carbon-carbon bonds through nucleophilic addition reactions.
What are the physicochemical properties of magnesium;carbanide;bromide?
Magnesium;carbanide;bromide is typically a crystalline solid or exists in solution form, commonly in anhydrous ether solvents. The compound is highly reactive with water and moisture, decomposing rapidly upon contact. It exhibits high reactivity due to the polar carbon-magnesium bond, making it extremely sensitive to protic solvents and requiring strictly anhydrous conditions for stability and effectiveness.
What is magnesium;carbanide;bromide used for?
Magnesium;carbanide;bromide is primarily used as a Grignard reagent in organic synthesis for pharmaceutical and chemical manufacturing. It serves as a nucleophilic methylating agent in the formation of carbon-carbon bonds, enabling the synthesis of alcohols, ketones, and other organic compounds. The compound is essential in fine chemical production, drug intermediate synthesis, and research applications requiring precise organic transformations.
How to handle magnesium;carbanide;bromide safely?
Magnesium;carbanide;bromide requires handling under strict anhydrous conditions using appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and laboratory coats. Work must be conducted in well-ventilated areas or under inert atmosphere to prevent moisture contact. All manipulations should occur in fume hoods, and personnel must be trained in organometallic compound handling procedures to prevent dangerous reactions with water or protic substances.
How to store magnesium;carbanide;bromide correctly?
Magnesium;carbanide;bromide must be stored under strictly anhydrous conditions, typically in sealed containers under inert gas atmosphere such as nitrogen or argon. Storage areas should be cool, dry, and separated from water, alcohols, and other protic solvents. The compound should be kept away from oxidizing agents and maintained at stable temperatures to prevent decomposition and ensure product integrity.
What to do in case of contact with magnesium;carbanide;bromide?
Immediate removal from the affected area is essential if contact with magnesium;carbanide;bromide occurs. For skin contact, brush off any solid material and flush with copious amounts of water, then seek medical attention. In case of eye contact, rinse immediately with water for at least 15 minutes. If inhaled, move to fresh air immediately. Never use water directly on bulk quantities due to violent reaction potential.
How to dispose of magnesium;carbanide;bromide appropriately?
Magnesium;carbanide;bromide disposal requires careful quenching with isopropanol or other suitable protic solvents under controlled conditions to neutralize reactivity. The resulting waste must be handled according to local hazardous waste regulations and disposed of through licensed chemical waste management companies. Never dispose of unreacted material in standard waste streams due to its reactive nature and potential environmental impact.
How to transport magnesium;carbanide;bromide?
Magnesium;carbanide;bromide is classified under ADR Class 4.3 (substances which, in contact with water, emit flammable gases), Packing Group I, indicating high danger level. Transportation requires specialized packaging that prevents moisture ingress and complies with dangerous goods regulations. Shipments must be properly labeled, documented, and handled by trained personnel familiar with water-reactive substance transport requirements.
Is magnesium;carbanide;bromide subject to particular regulations?
Magnesium;carbanide;bromide is subject to standard chemical regulations including REACH registration requirements in Europe and CLP classification for hazard communication. While not identified as a SVHC (Substance of Very High Concern), it must comply with occupational safety regulations due to its reactive nature. Users must maintain safety data sheets and implement appropriate risk management measures according to local chemical safety legislation.
Where to buy magnesium;carbanide;bromide in Europe?
Magnesium;carbanide;bromide is available through OYSI, a specialized European distributor of technical chemicals serving the pharmaceutical and chemical manufacturing industries. OYSI provides reliable supply chains for organometallic compounds, ensuring proper handling, storage, and transportation according to regulatory requirements. Contact OYSI directly for availability, specifications, and delivery options tailored to your specific application requirements.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.