Magnesium;carbanide;bromide

CH3BrMg

magnesium;carbanide;bromide

CAS75-16-1

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Identification

CAS Number
75-16-1
EC Number
200-844-1
UN Number
1928
PubChem CID
6349

Physical-chemical properties

Molecular Formula
CH3BrMg
Molar Mass
119.24 g/mol
IUPAC Name
magnesium;carbanide;bromide

Chemical Identifiers

InChI
InChI=1S/CH3.BrH.Mg/h1H3;1H;/q-1;;+2/p-1
InChI Key
NXPHGHWWQRMDIA-UHFFFAOYSA-M

Overview

Magnesium carbanide bromide (CAS 75-16-1) is an organometallic Grignard reagent with highly reactive carbon-magnesium bonds used in organic synthesis. This chemical compound, with the molecular formula CH3BrMg and molecular weight of 119.24 g/mol, represents one of the most fundamental and widely utilized Grignard reagents in organic chemistry. Also known by its IUPAC designation as magnesium carbanide bromide, this organometallic compound plays a crucial role in carbon-carbon bond formation reactions across numerous industrial and laboratory applications. The compound exhibits the characteristic properties of Grignard reagents, featuring a polar covalent bond between carbon and magnesium that makes it extremely nucleophilic and reactive toward electrophilic centers. This reactivity profile necessitates careful handling under strictly anhydrous conditions, as the compound reacts violently with water and other protic solvents. The ADR classification 4.3 indicates its water-reactive nature, requiring specialized storage and transportation protocols to maintain stability and prevent dangerous reactions. Key industrial applications include pharmaceutical intermediate synthesis, where it serves as a critical building block for complex organic molecules, fine chemical manufacturing for specialty compounds, and polymer chemistry for controlled polymerization processes. Unlike simpler organometallic compounds such as alumane or silane, magnesium carbanide bromide offers superior selectivity in nucleophilic addition reactions while maintaining reasonable stability under controlled conditions. The compound's versatility in forming new carbon-carbon bonds makes it indispensable for producing alcohols, ketones, and carboxylic acids through reactions with various carbonyl compounds. OYSI maintains reliable supply chains for this essential organometallic reagent to support European chemical manufacturing operations.

Safety & Classification

No Hazard Classification

This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.

Transport (ADR)

UN Number1928
ADR Class4.3
Packing GroupI
Tunnel CodeB/E
Proper Shipping NameMethylmagnesiumbromid in Ethylether
Marine PollutantNo

Frequently Asked Questions

What is magnesium;carbanide;bromide?

Magnesium carbanide bromide (CH3BrMg) is an organometallic compound with CAS number 75-16-1 and molecular weight 119.24 g/mol. This substance represents a Grignard reagent, specifically methylmagnesium bromide, which is formed by the reaction of magnesium metal with methyl bromide in anhydrous ether. It appears as a solution and is highly reactive with water and moisture, making it an important intermediate in organic synthesis for forming carbon-carbon bonds.

What are the physicochemical properties of magnesium;carbanide;bromide?

Magnesium carbanide bromide exists as a solution in anhydrous ether or THF at room temperature. The compound is extremely moisture-sensitive and reacts violently with water, producing methane gas and magnesium hydroxide. It has a molecular formula of CH3BrMg with a molar mass of 119.24 g/mol. The solution is typically colorless to pale yellow and must be kept under inert atmosphere due to its high reactivity with air and moisture.

What is magnesium;carbanide;bromide used for?

Magnesium carbanide bromide serves as a crucial Grignard reagent in organic synthesis for pharmaceutical, agrochemical, and fine chemical manufacturing. It enables the formation of carbon-carbon bonds by reacting with carbonyl compounds, nitriles, and other electrophiles to produce alcohols, ketones, and carboxylic acids. The compound is extensively used in research laboratories and industrial processes for synthesizing complex organic molecules, making it indispensable in modern organic chemistry applications.

How to handle magnesium;carbanide;bromide safely?

Magnesium carbanide bromide requires handling under strict anhydrous conditions using inert gas atmosphere (nitrogen or argon). Essential PPE includes chemical-resistant gloves, safety goggles, and lab coat. Work must be conducted in a well-ventilated fume hood away from water sources and moisture. Use dry glassware and syringes for transfer operations. Keep fire extinguishing equipment nearby as the compound can generate flammable gases. Never allow contact with water or alcohols during handling procedures.

How to store magnesium;carbanide;bromide correctly?

Magnesium carbanide bromide must be stored under inert atmosphere in tightly sealed containers at temperatures between 2-8°C. Keep containers away from moisture, water, alcohols, and acids which are incompatible and cause violent reactions. Store in a dry, well-ventilated area away from heat sources and ignition. Use amber glass bottles or steel containers suitable for air-sensitive materials. Regular integrity checks of sealing systems are essential to prevent moisture ingress and degradation.

What to do in case of contact with magnesium;carbanide;bromide?

Magnesium carbanide bromide contact requires immediate action due to its caustic nature. For skin contact, brush off any solid material and flush with copious amounts of water for 15 minutes while removing contaminated clothing. For eye contact, rinse immediately with water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. Never use water directly on spilled material as it causes violent reaction. Seek immediate medical attention for all exposure incidents.

How to dispose of magnesium;carbanide;bromide appropriately?

Magnesium carbanide bromide disposal requires careful quenching with isopropanol or careful addition to ice-cold water under controlled conditions to prevent violent reactions. The resulting aqueous solution can then be neutralized and disposed of according to local environmental regulations. Never dispose of unreacted material directly into drains or environment. Contact specialized chemical waste disposal companies familiar with organometallic compounds. Follow all applicable national and EU waste disposal regulations for hazardous chemical substances.

How to transport magnesium;carbanide;bromide?

Magnesium carbanide bromide is classified under ADR Class 4.3 (substances which emit flammable gases in contact with water), Packing Group I, indicating high danger level. Transport requires specialized packaging that prevents moisture ingress and meets UN specification standards. Vehicles must carry appropriate placarding and emergency response information. Shipments require dangerous goods documentation and trained personnel. The compound cannot be transported by air due to its reactive nature and must use road/rail transport under strict ADR compliance.

Is magnesium;carbanide;bromide subject to specific regulations?

Magnesium carbanide bromide falls under REACH regulation requiring registration for quantities above one tonne per year. The substance is not classified as SVHC (Substance of Very High Concern) under current EU regulations. However, its reactive nature means it must comply with workplace safety regulations and proper risk assessments. Users must maintain safety data sheets and follow occupational exposure limits. Transport is regulated under ADR Class 4.3 requirements for water-reactive substances.

Where to buy magnesium;carbanide;bromide in Europe?

Magnesium carbanide bromide is available through OYSI, a specialized European distributor of technical chemicals serving research institutions and industrial customers across Europe. OYSI provides this organometallic compound with appropriate technical documentation, safety data sheets, and regulatory compliance certificates. As a technical chemical requiring specialized handling and storage, it's available in various concentrations and solvents to meet specific research and industrial synthesis requirements. Contact OYSI directly for availability, specifications, and delivery options.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.