[(E)-4-(dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate

[(E)-4-(dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate is an organophosphorus compound with the molecular formula C8H16NO5P and CAS number 141-66-2. This chemical substance has a molecular weight of 237.19 g/mol and belongs to the class of phosphate esters. It is classified as highly toxic with acute toxicity categories 2 and 3, requiring careful handling due to its dangerous properties for both human health and aquatic environments.

[(E)-4-(dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate is an organic phosphate ester with a molecular weight of 237.19 g/mol. The compound contains both phosphate and amide functional groups, giving it specific chemical reactivity. As an organophosphorus compound, it typically exhibits moderate to high polarity due to the phosphate group, which influences its solubility characteristics and chemical behavior in various media.

[(E)-4-(dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate is primarily used as an intermediate in organic synthesis and chemical manufacturing processes. Organophosphorus compounds of this type are commonly employed in pharmaceutical synthesis, agrochemical production, and specialty chemical manufacturing. Due to its high toxicity classification, its use is restricted to professional and industrial applications where appropriate safety measures and expertise are available.

[(E)-4-(dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate requires strict safety precautions due to its Acute Tox. 2 and 3 classifications. Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. The GHS06 pictogram indicates skull and crossbones hazard, emphasizing the need for expert handling and training.

[(E)-4-(dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate must be stored in a secure, temperature-controlled environment away from incompatible materials. Keep containers tightly sealed and store in a designated hazardous materials area with appropriate ventilation. Due to its high toxicity classification (Acute Tox. 2/3), access should be restricted to trained personnel only. Ensure proper labeling with GHS06 and GHS09 pictograms and maintain safety data sheets readily available.

Immediate medical attention is required for any contact with [(E)-4-(dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate due to its Acute Tox. 2/3 classification. For skin contact, immediately flush with copious amounts of water and remove contaminated clothing. If inhaled, move to fresh air immediately. For eye contact, rinse thoroughly with water. Do not induce vomiting if ingested. Contact poison control or emergency medical services immediately and provide the safety data sheet.

[(E)-4-(dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate must be disposed of as hazardous waste through licensed waste management companies. Due to its acute toxicity and aquatic toxicity classifications (Aquatic Acute 1, Aquatic Chronic 1), it cannot be discharged to sewers or the environment. Follow local and European waste regulations (EU Waste Framework Directive). Ensure proper documentation and use authorized disposal facilities specializing in toxic organophosphorus compounds.

[(E)-4-(dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate is classified under ADR Class 6.1 (Toxic substances), Packing Group II. Transport requires appropriate UN-specification packaging, proper labeling with Class 6.1 hazard labels, and shipping documentation. Only authorized carriers trained in hazardous materials transport should handle shipments. The substance requires special handling procedures due to its high toxicity classification and must comply with European ADR regulations for dangerous goods transport.

[(E)-4-(dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate is subject to REACH regulation and CLP classification requirements in Europe. While not currently listed as an SVHC (Substance of Very High Concern), its high toxicity classification requires compliance with occupational exposure limits and safety data sheet provisions. Users must ensure proper risk assessment, worker protection measures, and environmental safeguards. Registration requirements under REACH may apply depending on import/manufacturing volumes.

[(E)-4-(dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this highly toxic compound to qualified industrial and research customers with appropriate handling capabilities. Due to the substance's Acute Tox. 2/3 classification and regulatory requirements, purchases are restricted to professional users who can demonstrate proper safety measures, storage facilities, and waste disposal arrangements.