2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione

C14H17ClNO4PS2

CAS10311-84-9
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
10311-84-9
EC Number
233-689-3
UN Number
2783
Index Number
015-088-00-6
PubChem CID
25146

Physical-chemical properties

Molecular Formula
C14H17ClNO4PS2
Molar Mass
393.80 g/mol
IUPAC Name
2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione

Chemical Identifiers

InChI
InChI=1S/C14H17ClNO4PS2/c1-3-19-21(22,20-4-2)23-12(9-15)16-13(17)10-7-5-6-8-11(10)14(16)18/h5-8,12H,3-4,9H2,1-2H3
InChI Key
MUMQYXACQUZOFP-UHFFFAOYSA-N

Overview

2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione (CAS 10311-84-9) is an organophosphorus compound with phthalimide functionality and significant toxicological properties. This specialized chemical compound, with molecular formula C14H17ClNO4PS2 and molecular weight 393.8 g/mol, represents a complex organophosphorus derivative incorporating both phthalimide and phosphorothioate structural elements. The molecule features a distinctive architecture combining an isoindole-1,3-dione core with a chlorinated ethyl chain linked to a diethoxyphosphinothioyl group through a sulfur bridge. This unique structural arrangement places it within the broader category of organophosphorus compounds that share certain characteristics with related substances such as diethoxy-(2-ethylsulfinylethylsulfanyl)-sulfanylidene-lambda5-phosphane, though each compound exhibits distinct properties and applications. The compound is classified under multiple acute toxicity categories (Acute Tox. 2 and 3) and presents significant environmental hazards as indicated by its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Transport regulations categorize it under ADR Class 6.1, reflecting its toxic nature, with GHS06 and GHS09 pictograms emphasizing both toxicity and environmental hazards. The "Danger" signal word underscores the need for specialized handling protocols and appropriate safety measures during storage, transport, and use. Industrial applications typically focus on specialized chemical synthesis processes where the compound's unique reactivity profile proves valuable. The phosphorothioate functionality makes it particularly useful in certain agrochemical intermediate synthesis and specialized organic transformations. Additionally, its phthalimide component can serve as a protective group in complex synthetic pathways, particularly in pharmaceutical intermediate manufacturing. OYSI provides this specialized organophosphorus compound to European industrial customers requiring high-quality chemical intermediates for advanced synthesis applications.

Safety & Classification

Danger
Classification:

Acute Tox. 3 *; Acute Tox. 2 *; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H311

Toxic in contact with skin.

H300

Fatal if swallowed.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2783
ADR Class6.1
Packing GroupI
Tunnel CodeC/E
Proper Shipping NameDialifos (ISO)
Marine PollutantNo

Frequently Asked Questions

What is 2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione?

2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione is an organophosphorus compound with CAS number 10311-84-9 and molecular formula C14H17ClNO4PS2. This chemical substance has a molecular weight of 393.8 g/mol and features both phosphorus-sulfur bonds and an isoindole-dione structure. It is classified as a highly toxic substance with significant environmental hazards, requiring careful handling and specialized safety measures in industrial applications.

What are the physicochemical properties of 2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione?

2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione is a complex organophosphorus compound with a molecular weight of 393.8 g/mol. The substance contains chlorine, nitrogen, oxygen, phosphorus, and sulfur atoms within its molecular structure. As an organophosphorus compound with isoindole-dione functionality, it typically exhibits limited water solubility and requires organic solvents for dissolution. Specific physical properties such as melting point, boiling point, and exact solubility data should be obtained from detailed safety data sheets.

What is 2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione used for?

2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione is primarily used in specialized chemical synthesis and research applications. Given its organophosphorus structure with isoindole-dione functionality, it may serve as an intermediate in pharmaceutical synthesis or as a reagent in organic chemistry research. The compound's specific applications are typically limited to professional laboratory settings and specialized industrial processes due to its high toxicity classification and environmental hazard profile.

How to handle 2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione safely?

2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione requires extensive safety precautions due to its Acute Toxicity 2 and 3 classifications. Personnel must wear complete personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work should only be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Handle containers carefully to prevent spills, and ensure emergency shower and eyewash stations are readily accessible.

How to store 2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione correctly?

2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione must be stored in a secure, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly sealed and store in original packaging with proper hazard labeling. Due to its high toxicity and environmental hazard classification, storage should be in designated areas with restricted access, secondary containment, and appropriate spill response materials. Maintain storage temperature as specified on the safety data sheet and regularly inspect containers for damage or leaks.

What to do in case of contact with 2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione?

Immediate medical attention is required for any contact with 2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione due to its high toxicity. For skin contact, remove contaminated clothing and flush affected area with copious amounts of water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, rinse thoroughly with water for at least 15 minutes. Never induce vomiting if ingested. Contact emergency services and poison control center immediately, providing the safety data sheet to medical personnel.

How to dispose of 2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione appropriately?

2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione must be disposed of as hazardous waste through licensed waste management companies. Due to its classification as ADR Class 6.1 Group I and environmental hazard status, it cannot be disposed of through normal waste streams. Waste disposal must comply with local, national, and EU regulations including the Waste Framework Directive. Containers should be properly labeled, and disposal documentation must be maintained for regulatory compliance.

How to transport 2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione?

2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione is classified under ADR Class 6.1 (Toxic substances), Packing Group I, indicating the highest level of toxicity. Transportation requires specialized packaging, proper hazard labeling with GHS06 and GHS09 pictograms, and appropriate shipping documentation. Only certified carriers trained in dangerous goods transport should handle shipments. Vehicles must carry emergency response equipment, and drivers require ADR certification for toxic substance transport under European regulations.

Is 2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione subject to particular regulations?

2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione is subject to extensive chemical regulations including REACH registration requirements and CLP classification as Acute Tox. 2/3 and Aquatic hazard categories. While not currently listed as an SVHC, it requires safety data sheets, proper labeling with 'Danger' signal word, and compliance with occupational exposure limits. Transportation is regulated under ADR dangerous goods regulations, and use may be restricted in certain applications due to its high toxicity and environmental impact.

Where to buy 2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione in Europe?

2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione is available through OYSI, a specialized European distributor of technical chemicals. As this substance requires specialized handling due to its high toxicity classification, OYSI provides proper documentation, safety data sheets, and regulatory compliance support. Given the substance's ADR Class 6.1 Group I classification, procurement is typically limited to qualified industrial users with appropriate handling capabilities and regulatory permits for toxic substances.

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2-(2-chloro-1-diethoxyphosphinothioylsulfanylethyl)isoindole-1,3-dione is a dangerous good. We support you with labeling, packaging, and transport documentation.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.