Diethoxy-[(5-phenyl-1,2-oxazol-3-yl)oxy]-sulfanylidene-lambda5-phosphane

Diethoxy-[(5-phenyl-1,2-oxazol-3-yl)oxy]-sulfanylidene-lambda5-phosphane is an organophosphorus compound with the molecular formula C13H16NO4PS and CAS number 18854-01-8. This chemical features a phosphorus center bonded to diethoxy groups and a phenyl-substituted oxazole ring system. With a molecular weight of 313.31 g/mol, it belongs to the class of phosphorothioate derivatives and is classified as a hazardous substance requiring careful handling due to its acute toxicity and environmental impact.

Diethoxy-[(5-phenyl-1,2-oxazol-3-yl)oxy]-sulfanylidene-lambda5-phosphane is an organophosphorus compound with a molecular weight of 313.31 g/mol and formula C13H16NO4PS. The compound contains both hydrophobic aromatic components and polar phosphate groups, which influence its solubility characteristics. As a phosphorothioate derivative with an oxazole ring system, it exhibits stability under normal conditions but requires protection from moisture and extreme temperatures. Its physicochemical behavior is typical of organophosphorus compounds used in specialized chemical applications.

Diethoxy-[(5-phenyl-1,2-oxazol-3-yl)oxy]-sulfanylidene-lambda5-phosphane is primarily used as a specialized intermediate in pharmaceutical and agrochemical synthesis. Its unique phosphorothioate structure with an oxazole ring makes it valuable for developing bioactive compounds and pesticide formulations. The compound serves as a building block in organic synthesis, particularly in reactions requiring phosphorus-containing functionalities. Industrial applications include use in research laboratories and chemical manufacturing facilities producing fine chemicals and active pharmaceutical ingredients.

Diethoxy-[(5-phenyl-1,2-oxazol-3-yl)oxy]-sulfanylidene-lambda5-phosphane requires strict safety measures due to its Acute Tox. 3 classification and Danger signal word. Essential PPE includes chemical-resistant gloves, safety goggles, and respiratory protection when handling. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and ensure emergency eyewash stations are accessible. The compound displays GHS06 and GHS09 pictogrammes, indicating both toxicity and environmental hazards requiring careful containment.

Diethoxy-[(5-phenyl-1,2-oxazol-3-yl)oxy]-sulfanylidene-lambda5-phosphane must be stored in a cool, dry place away from direct sunlight and heat sources. Storage areas should be well-ventilated and equipped with spill containment measures due to its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1). Keep containers tightly sealed to prevent moisture ingress and contamination. Store separately from incompatible materials such as strong oxidizers and bases. Access should be restricted to trained personnel, and storage areas must comply with local regulations for toxic substances.

Immediate action is required if contact occurs with diethoxy-[(5-phenyl-1,2-oxazol-3-yl)oxy]-sulfanylidene-lambda5-phosphane due to its Acute Tox. 3 classification. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for 15-20 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a poison control center or physician.

Diethoxy-[(5-phenyl-1,2-oxazol-3-yl)oxy]-sulfanylidene-lambda5-phosphane requires specialized disposal as hazardous waste due to its toxicity and environmental impact classifications. Disposal must comply with local, national, and EU waste regulations, particularly those governing toxic substances (Acute Tox. 3) and environmentally hazardous materials (Aquatic Acute 1, Aquatic Chronic 1). Contact licensed hazardous waste disposal companies for proper treatment and destruction. Never dispose of in regular waste streams, sewers, or waterways. Maintain detailed disposal records and ensure proper waste classification codes are used.

Diethoxy-[(5-phenyl-1,2-oxazol-3-yl)oxy]-sulfanylidene-lambda5-phosphane is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation purposes. Transport must comply with dangerous goods regulations using appropriate UN-approved packaging and labeling. Vehicles must carry proper documentation including transport documents and emergency response information. Drivers require ADR certification for Class 6.1 materials. Packages must display the required hazard labels (toxic substance pictogrammes) and proper shipping names. Ensure adequate segregation from incompatible materials during transport and follow routing restrictions for toxic goods.

Diethoxy-[(5-phenyl-1,2-oxazol-3-yl)oxy]-sulfanylidene-lambda5-phosphane is not currently identified as a Substance of Very High Concern (SVHC) under REACH regulation. However, it remains subject to standard REACH registration requirements, CLP classification and labeling obligations, and ADR transport regulations due to its Class 6.1 classification. The compound must comply with occupational exposure limits and environmental protection measures given its aquatic toxicity classifications. Users must maintain safety data sheets, implement appropriate risk management measures, and ensure worker protection according to EU chemical safety legislation.

Diethoxy-[(5-phenyl-1,2-oxazol-3-yl)oxy]-sulfanylidene-lambda5-phosphane is available through OYSI, a specialized European distributor of technical chemicals and laboratory reagents. OYSI provides this compound to qualified industrial customers, research institutions, and chemical manufacturers across Europe. As a regulated substance requiring proper handling credentials, purchases are subject to end-use verification and appropriate documentation. Contact OYSI directly for availability, technical specifications, and regulatory compliance support. The compound is typically supplied in appropriate packaging meeting ADR Class 6.1 transport requirements and safety standards.