Arsenic

As

arsenic

CAS7440-38-2
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
7440-38-2
EC Number
231-148-6
UN Number
1558
Index Number
033-001-00-X
PubChem CID
5359596

Physical-chemical properties

Molecular Formula
As
Molar Mass
74.92 g/mol
IUPAC Name
arsenic

Chemical Identifiers

InChI
InChI=1S/As
InChI Key
RQNWIZPPADIBDY-UHFFFAOYSA-N

Overview

Arsenic (CAS 7440-38-2) is a metalloid element with high toxicity and semiconducting properties found naturally in the earth's crust. This chemical element, with the molecular formula As and atomic number 33, represents one of the most historically significant yet hazardous substances in industrial chemistry. Arsenic exists in several allotropic forms, with metallic arsenic appearing as a steel-gray, brittle crystalline solid under standard conditions. With a molecular weight of 74.92159 g/mol, this metalloid demonstrates unique properties that bridge the gap between metals and non-metals, making it valuable for specific industrial applications despite its notorious toxicity profile. The safety classification of arsenic reflects its severe health hazards, carrying Acute Toxicity Category 3 ratings and requiring the "Danger" signal word with GHS06 and GHS09 pictograms. Its environmental impact is equally concerning, classified as Aquatic Acute 1 and Aquatic Chronic 1, indicating immediate and long-term threats to aquatic ecosystems. Transportation regulations classify arsenic under ADR Class 6.1, emphasizing the stringent handling requirements necessary for safe distribution. Industrial applications of arsenic remain limited but critical in certain sectors. The semiconductor industry utilizes high-purity arsenic for gallium arsenide production, essential for electronic devices and solar cells. Wood preservation historically represented a major application, though environmental concerns have significantly reduced this usage. Unlike more complex compounds such as ethyl 2-[[5-tert-butyl-2-(dimethylcarbamoyl)-1,2,4-triazol-3-yl]sulfanyl]acetate used in agricultural applications, elemental arsenic serves primarily in specialized metallurgical and electronic manufacturing processes. OYSI maintains availability of technical-grade arsenic for qualified industrial customers, ensuring compliance with all European regulatory requirements and safety protocols.

Safety & Classification

Danger
Classification:

Acute Tox. 3 *; Acute Tox. 3 *; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H331

Toxic if inhaled.

H301

Toxic if swallowed.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1558
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameArsen, metallisch
Marine PollutantNo

Frequently Asked Questions

What is arsenic?

Arsenic is a naturally occurring metalloid element with the chemical symbol As and atomic number 33. This toxic substance appears as a gray, brittle solid in its pure form and has been known since ancient times. With a molecular weight of 74.92159 g/mol, arsenic exhibits both metallic and non-metallic properties, making it useful in various industrial applications despite its high toxicity to humans and environmental organisms.

What are the physicochemical properties of arsenic?

Arsenic is a gray, brittle metalloid solid at room temperature with no characteristic odor. It has a density of 5.727 g/cm³ and sublimes at 616°C without melting under normal atmospheric pressure. The element is poorly soluble in water but dissolves in acids and alkalis. It exists in several allotropic forms, with the gray metallic form being the most stable and common variant used in industrial applications.

What is arsenic used for?

Arsenic is primarily used in the semiconductor industry for manufacturing gallium arsenide compounds in electronic devices and solar cells. It serves as an alloying agent in lead-based materials to improve hardness and corrosion resistance. Additionally, arsenic compounds are utilized in wood preservatives, pesticides, and specialized glass production. The pharmaceutical industry also uses certain arsenic compounds in specific medical treatments, though this application is highly regulated due to toxicity concerns.

How to handle arsenic safely?

Arsenic must be handled with extreme caution using appropriate personal protective equipment including respirators, chemical-resistant gloves, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Direct skin contact must be avoided at all costs, and eating, drinking, or smoking in work areas is strictly prohibited. Regular health monitoring and proper training are essential for personnel handling this highly toxic substance.

How to store arsenic correctly?

Arsenic must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers and acids. Storage areas should be secure and accessible only to authorized personnel with proper training. The storage location must be clearly labeled with appropriate hazard warnings and equipped with emergency response materials. Regular container inspections are necessary to ensure integrity and prevent environmental contamination.

What to do in case of contact with arsenic?

Arsenic exposure requires immediate emergency response depending on the contact route. For skin contact, remove contaminated clothing and rinse the affected area with plenty of water for at least 15 minutes. If inhaled, move the person to fresh air immediately and seek medical attention. In case of ingestion, do not induce vomiting and contact poison control immediately. All exposure incidents require prompt medical evaluation due to arsenic's severe toxicity and potential for systemic poisoning.

How to dispose of arsenic properly?

Arsenic disposal must comply with strict hazardous waste regulations and cannot be disposed of with regular waste. The material must be collected by licensed hazardous waste disposal companies and treated at specialized facilities. Contaminated materials, containers, and protective equipment must also be handled as hazardous waste. Proper documentation and waste tracking are required throughout the disposal process to ensure environmental protection and regulatory compliance.

How to transport arsenic?

Arsenic is classified as dangerous goods under ADR regulations as Class 6.1 (toxic substances) Packing Group II. Transportation requires proper UN-approved packaging, hazard labels, and shipping documentation. Drivers must have appropriate dangerous goods training certificates, and vehicles must carry emergency response information. The transport must follow designated routes and comply with quantity limitations and segregation requirements to ensure public safety during transit.

Is arsenic subject to particular regulations?

Arsenic is heavily regulated under multiple European frameworks including REACH, CLP, and various national restrictions due to its high toxicity. The substance requires registration under REACH for commercial use and is subject to strict occupational exposure limits. Environmental discharge is regulated under water and air quality directives, and its use in consumer products is severely restricted or banned in many applications to protect public health.

Where to buy arsenic in Europe?

Arsenic is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the continent. As a regulated toxic substance, arsenic sales are restricted to qualified industrial users with proper licenses and safety protocols. OYSI ensures compliance with all regulatory requirements and provides technical support for safe handling. Contact OYSI directly to discuss your specific requirements and verify regulatory compliance for your intended application.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.