5,7-dichloro-4-oxo-1H-quinoline-3-carboxylic acid

5,7-dichloro-4-oxo-1H-quinoline-3-carboxylic acid is a synthetic organic compound belonging to the quinoline carboxylic acid family. With the molecular formula C10H5Cl2NO3 and CAS number 171850-30-9, this chlorinated quinoline derivative has a molecular weight of 258.05 g/mol. The compound features two chlorine substituents at positions 5 and 7 of the quinoline ring system, along with a carboxylic acid group at position 3 and a ketone function at position 4.

5,7-dichloro-4-oxo-1H-quinoline-3-carboxylic acid is a solid crystalline compound at room temperature. As a quinoline derivative with chlorine substituents and carboxylic acid functionality, it typically appears as a pale yellow to off-white powder. The compound exhibits limited water solubility due to its aromatic structure, but may dissolve in polar organic solvents and alkaline solutions due to the carboxylic acid group. Its melting point and other specific physical properties require laboratory determination.

5,7-dichloro-4-oxo-1H-quinoline-3-carboxylic acid is primarily used as an intermediate in pharmaceutical and fine chemical synthesis. Quinoline carboxylic acid derivatives are important building blocks for developing antimicrobial agents, particularly fluoroquinolone antibiotics. This specific compound may serve as a precursor for synthesizing various bioactive molecules or as a research chemical in medicinal chemistry applications. Its chlorinated structure makes it valuable for further chemical modifications and drug development processes.

5,7-dichloro-4-oxo-1H-quinoline-3-carboxylic acid should be handled with standard laboratory safety precautions. Wear appropriate personal protective equipment including safety glasses, gloves, and lab coat. Work in a well-ventilated area or under a fume hood to avoid inhalation of dust particles. As it is classified as Aquatic Chronic 2, prevent environmental release. Use proper weighing techniques to minimize dust generation and ensure good hygiene practices by washing hands after handling.

5,7-dichloro-4-oxo-1H-quinoline-3-carboxylic acid should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight. Keep the compound at room temperature or below to maintain stability. Store away from strong oxidizing agents and bases that might react with the carboxylic acid group. Ensure containers are properly labeled and stored in designated chemical storage areas with appropriate secondary containment to prevent environmental contamination.

In case of skin contact with 5,7-dichloro-4-oxo-1H-quinoline-3-carboxylic acid, immediately wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, rinse thoroughly with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Remove contaminated clothing and wash before reuse. Always consult a physician if irritation persists.

5,7-dichloro-4-oxo-1H-quinoline-3-carboxylic acid must be disposed of as hazardous chemical waste through licensed waste management companies. Due to its Aquatic Chronic 2 classification, prevent release to water systems or soil. Collect waste in appropriate containers, clearly labeled with contents and hazard information. Small quantities may be suitable for incineration at authorized high-temperature facilities. Always follow local, national, and EU waste regulations, and consult your waste disposal contractor for specific guidance on quinoline derivatives.

5,7-dichloro-4-oxo-1H-quinoline-3-carboxylic acid is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III. Transport requires appropriate UN specification packaging and proper shipping documentation. Packages must be clearly marked and labeled with the correct shipping name and UN number. Ensure vehicles are properly placarded and drivers hold appropriate dangerous goods training certificates. Follow ADR regulations for loading, segregation, and documentation requirements during European transport.

5,7-dichloro-4-oxo-1H-quinoline-3-carboxylic acid is subject to REACH regulation requiring registration for manufacture or import above 1 tonne per year. Under CLP regulation, it is classified as Aquatic Chronic 2 requiring GHS09 environmental pictogram on labels. The compound is not currently listed as SVHC (Substance of Very High Concern). Users must comply with safety data sheet requirements and ensure appropriate risk assessments are conducted for intended uses within their chemical safety programs.

5,7-dichloro-4-oxo-1H-quinoline-3-carboxylic acid is available through OYSI, a specialized European distributor of fine chemicals and pharmaceutical intermediates. OYSI offers reliable supply chains across Europe with proper regulatory compliance and documentation. As a technical chemical distributor, OYSI ensures products meet quality specifications and provides comprehensive safety data sheets and certificates of analysis. Contact OYSI directly for availability, specifications, packaging options, and delivery throughout European markets.