(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone

(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone is an organic compound with the molecular formula C15H12F3NO4S and CAS number 141112-29-0. This complex molecule features an oxazole ring system combined with a trifluoromethyl-substituted phenyl group connected via a methanone bridge. With a molecular weight of 359.3 g/mol, it belongs to the class of fluorinated organic compounds and is classified as having reproductive toxicity and aquatic toxicity properties.

The compound exhibits typical properties of fluorinated organic molecules with its molecular formula C15H12F3NO4S and molecular weight of 359.3 g/mol. The presence of trifluoromethyl groups typically imparts chemical stability and influences solubility characteristics. The oxazole ring and methylsulfonyl substituents contribute to the compound's polarity. Specific physical properties such as melting point, boiling point, and exact solubility data would require detailed analytical characterization for precise determination.

This compound is primarily used as an intermediate in pharmaceutical and agrochemical synthesis due to its complex heterocyclic structure containing oxazole and trifluoromethyl functionalities. Such compounds are valuable building blocks in medicinal chemistry for developing bioactive molecules. The specific structural features make it suitable for applications requiring fluorinated scaffolds, particularly in the development of compounds with enhanced metabolic stability and bioactivity. Its use is typically restricted to professional industrial applications.

Safe handling requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Repr. 2 classification. Work should be conducted in well-ventilated areas or under fume extraction systems to prevent inhalation exposure. Avoid skin and eye contact, and prevent release to the environment given its aquatic toxicity classification (Aquatic Acute 1, Aquatic Chronic 1). Use proper handling techniques to minimize dust generation and ensure all personnel are trained in chemical safety procedures.

The compound should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Given its organic nature and functional groups, avoid exposure to strong oxidizing agents, strong bases, and sources of ignition. Storage areas should be equipped with appropriate containment measures to prevent environmental release due to its aquatic toxicity classification. Maintain proper inventory records and ensure storage complies with local chemical storage regulations and workplace safety requirements.

In case of skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and seek medical advice if symptoms persist. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet and contact emergency services if serious exposure occurs.

Disposal must be conducted through licensed hazardous waste disposal facilities due to its reproductive toxicity and aquatic toxicity classifications. The compound cannot be disposed of via standard waste streams or released to the environment. Waste should be properly labeled, containerized, and handled according to local and European waste regulations including the Waste Framework Directive. Small quantities should be collected and stored safely until sufficient volume is accumulated for cost-effective disposal through authorized waste management companies.

The compound is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III, indicating it poses a relatively lower but still significant transport risk. Transportation must comply with ADR regulations including proper packaging, labeling, and documentation requirements. Packages should bear appropriate UN markings and hazard labels. Transport should be conducted by carriers qualified for dangerous goods transport, with proper emergency response information available. Vehicle requirements and routing restrictions for Class 9 materials must be observed.

The compound is subject to European REACH regulation requiring registration for import/manufacture above tonnage thresholds, and CLP regulation for classification and labeling as Repr. 2, Aquatic Acute 1, and Aquatic Chronic 1. It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational exposure limits where established, and environmental discharge controls due to its aquatic toxicity. Industrial users may need to conduct chemical safety assessments and implement risk management measures.

OYSI serves as a reliable European distributor for this specialized chemical compound, providing professional-grade materials to qualified industrial customers. As a specialized chemical requiring proper handling and regulatory compliance, purchase is typically restricted to qualified industrial users, research institutions, and chemical professionals. OYSI ensures proper documentation, safety data sheets, and regulatory compliance for European customers. Contact OYSI directly to discuss availability, packaging options, and technical specifications for your specific application requirements.