5-chloro-2-(4-chlorophenoxy)phenol

C12H8Cl2O2

CAS3380-30-1
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
3380-30-1
EC Number
429-290-0
UN Number
3077
Index Number
605-023-00-5
PubChem CID
18807

Physical-chemical properties

Molecular Formula
C12H8Cl2O2
Molar Mass
255.09 g/mol
IUPAC Name
5-chloro-2-(4-chlorophenoxy)phenol

Chemical Identifiers

InChI
InChI=1S/C12H8Cl2O2/c13-8-1-4-10(5-2-8)16-12-6-3-9(14)7-11(12)15/h1-7,15H
InChI Key
BYNQFCJOHGOKSS-UHFFFAOYSA-N

Overview

5-chloro-2-(4-chlorophenoxy)phenol (CAS 3380-30-1) is a dichlorinated phenolic compound with antimicrobial and preservative properties. This specialized chemical substance belongs to the family of chlorinated phenolic derivatives, characterized by its dual chlorine substitution pattern that enhances its biological activity and stability. The compound features a phenoxyphenol backbone structure, where a 4-chlorophenoxy group is attached to a 5-chlorophenol moiety, resulting in a molecular formula of C12H8Cl2O2 and a molecular weight of 255.09 g/mol. The presence of two chlorine atoms significantly influences the compound's chemical behavior and antimicrobial efficacy. Like other phenolic compounds such as 4-(4-hydroxy-3-methylphenyl)sulfanyl-2-methylphenol, this substance exhibits notable biological activity, though with distinct selectivity profiles due to its unique substitution pattern. The compound's phenolic nature contributes to its ability to interact with biological membranes and proteins, making it valuable in various industrial applications. From a safety perspective, 5-chloro-2-(4-chlorophenoxy)phenol requires careful handling due to its classification as Eye Dam. 1, indicating severe eye damage potential. The substance also presents environmental concerns with Aquatic Acute 1 and Aquatic Chronic 1 classifications, necessitating appropriate containment and disposal measures. Transport regulations classify it under ADR Class 9 as a miscellaneous dangerous substance. Primary industrial applications include antimicrobial formulations, specialty preservative systems, and intermediate synthesis for pharmaceutical and agrochemical compounds. The compound's dual-chlorine structure provides enhanced stability and efficacy compared to single-substituted analogs. OYSI maintains reliable supply chains for 5-chloro-2-(4-chlorophenoxy)phenol, supporting European industrial customers with technical-grade material for specialized applications.

Safety & Classification

Danger
Classification:

Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H318

Causes serious eye damage.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name5-Chlor-2-(4-chlorphenoxy)phenol
Marine PollutantNo

Frequently Asked Questions

What is 5-chloro-2-(4-chlorophenoxy)phenol?

5-chloro-2-(4-chlorophenoxy)phenol is an organochlorine compound with the molecular formula C12H8Cl2O2 and CAS number 3380-30-1. This chemical substance has a molecular weight of 255.09 g/mol and belongs to the phenolic compounds family. It contains two chlorine atoms and exhibits significant environmental hazard properties, being classified as highly toxic to aquatic life with long-lasting effects.

What are the physicochemical properties of 5-chloro-2-(4-chlorophenoxy)phenol?

5-chloro-2-(4-chlorophenoxy)phenol is a solid crystalline compound at room temperature with a molecular weight of 255.09 g/mol. As a chlorinated phenolic derivative, it typically appears as a white to off-white crystalline powder. The compound has limited water solubility due to its hydrophobic chlorinated aromatic structure, making it more soluble in organic solvents than in aqueous media.

What is 5-chloro-2-(4-chlorophenoxy)phenol used for?

5-chloro-2-(4-chlorophenoxy)phenol is primarily used as an intermediate in pharmaceutical synthesis and chemical manufacturing processes. It serves as a building block for the production of more complex organic compounds, particularly in the development of antimicrobial agents and pharmaceutical active ingredients. The compound may also find applications in specialty chemical formulations requiring chlorinated phenolic structures.

How to handle 5-chloro-2-(4-chlorophenoxy)phenol safely?

5-chloro-2-(4-chlorophenoxy)phenol must be handled with extreme caution due to its Eye Dam. 1 classification causing serious eye damage. Wear appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Work in well-ventilated areas or under fume hoods to minimize exposure. Avoid direct contact with skin and eyes, and prevent environmental release due to its aquatic toxicity.

How to store 5-chloro-2-(4-chlorophenoxy)phenol correctly?

5-chloro-2-(4-chlorophenoxy)phenol should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly closed and protected from light and moisture. Store away from heat sources and oxidizing agents. Due to its environmental hazards, ensure proper containment to prevent accidental release. Maintain storage temperatures as recommended by the supplier and follow local regulations for hazardous chemical storage.

What to do in case of contact with 5-chloro-2-(4-chlorophenoxy)phenol?

In case of eye contact with 5-chloro-2-(4-chlorophenoxy)phenol, immediately flush with plenty of water for at least 15 minutes and seek immediate medical attention due to serious eye damage risk. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek medical attention immediately.

How to dispose of 5-chloro-2-(4-chlorophenoxy)phenol properly?

5-chloro-2-(4-chlorophenoxy)phenol must be disposed of as hazardous waste according to local and national regulations. Due to its aquatic toxicity classification, prevent any environmental release during disposal. Contact licensed hazardous waste disposal companies for proper treatment and destruction. Do not discharge into sewers, water courses, or onto the ground. Packaging materials should also be treated as contaminated waste requiring proper disposal.

How to transport 5-chloro-2-(4-chlorophenoxy)phenol?

5-chloro-2-(4-chlorophenoxy)phenol is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Use UN-approved packaging and ensure proper marking and placarding of transport vehicles. Transport documentation must include the substance's hazard classification and emergency response information.

Is 5-chloro-2-(4-chlorophenoxy)phenol subject to specific regulations?

5-chloro-2-(4-chlorophenoxy)phenol is subject to REACH regulation in Europe and must comply with CLP classification requirements. It is classified as Eye Dam. 1, Aquatic Acute 1, and Aquatic Chronic 1 under CLP regulation. The substance is not currently listed as SVHC (Substance of Very High Concern). Users must ensure proper registration, safety data sheet provision, and compliance with occupational exposure limits and environmental protection requirements.

Where to buy 5-chloro-2-(4-chlorophenoxy)phenol in Europe?

5-chloro-2-(4-chlorophenoxy)phenol is available through OYSI, a European distributor of specialty chemicals. OYSI provides quality chemical products with proper documentation, safety data sheets, and regulatory compliance for European markets. As an established chemical distributor, OYSI ensures proper handling, packaging, and delivery of this regulated substance while meeting all safety and environmental requirements for hazardous chemical distribution.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.