3-cyclohexyl-1,5,6,7-tetrahydrocyclopenta[d]pyrimidine-2,4-dione

3-cyclohexyl-1,5,6,7-tetrahydrocyclopenta[d]pyrimidine-2,4-dione is an organic chemical compound with the molecular formula C13H18N2O2 and CAS number 2164-08-1. This pyrimidine derivative has a molecular weight of 234.29 g/mol and features a complex bicyclic structure combining a cyclopentane ring fused to a pyrimidine core, with a cyclohexyl substituent. The compound is classified as a Category 2 carcinogen and presents aquatic toxicity concerns under CLP regulation.

3-cyclohexyl-1,5,6,7-tetrahydrocyclopenta[d]pyrimidine-2,4-dione is a solid organic compound at room temperature with a molecular weight of 234.29 g/mol. The substance contains nitrogen and oxygen functional groups within its heterocyclic structure, which influences its polarity and potential solubility characteristics. As a pyrimidine derivative with a cyclohexyl group, it exhibits moderate lipophilicity. Specific physical properties such as melting point, boiling point, and exact solubility data should be confirmed through technical documentation.

3-cyclohexyl-1,5,6,7-tetrahydrocyclopenta[d]pyrimidine-2,4-dione is primarily used as a chemical intermediate in pharmaceutical and fine chemical synthesis. Its pyrimidine structure makes it valuable for developing bioactive compounds and pharmaceutical intermediates. The substance may also serve as a building block in organic synthesis for research and development applications. Given its specific molecular structure, it is typically employed in specialized chemical manufacturing processes requiring precise molecular frameworks for drug discovery or advanced material applications.

3-cyclohexyl-1,5,6,7-tetrahydrocyclopenta[d]pyrimidine-2,4-dione requires careful handling due to its Category 2 carcinogenic classification. Essential safety measures include wearing appropriate personal protective equipment: nitrile gloves, safety goggles, and respiratory protection when handling powders. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid skin contact and ensure proper containment during transfers. Personnel should be trained on carcinogenic substance handling procedures and emergency response protocols before working with this material.

3-cyclohexyl-1,5,6,7-tetrahydrocyclopenta[d]pyrimidine-2,4-dione should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly sealed to prevent moisture absorption and contamination. Store in dedicated areas for carcinogenic substances with restricted access and appropriate labeling. Maintain temperatures below 25°C when possible and ensure compatibility with storage materials. Keep away from incompatible substances such as strong oxidizers and acids. Regular inventory checks and proper record-keeping are essential for carcinogenic materials.

Immediate decontamination is essential following contact with 3-cyclohexyl-1,5,6,7-tetrahydrocyclopenta[d]pyrimidine-2,4-dione. For skin contact, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush with clean water for at least 15 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. Seek medical attention promptly, especially given the carcinogenic classification. Provide the safety data sheet to medical personnel for proper treatment guidance.

3-cyclohexyl-1,5,6,7-tetrahydrocyclopenta[d]pyrimidine-2,4-dione must be disposed of as hazardous waste due to its carcinogenic classification and environmental toxicity. Contact licensed hazardous waste disposal companies authorized to handle carcinogenic substances. Never dispose of through regular waste streams or sewage systems due to its aquatic toxicity classification. Waste should be properly labeled, containerized, and documented according to local and European waste regulations. Incineration at licensed high-temperature facilities is typically the preferred disposal method for organic carcinogenic compounds.

3-cyclohexyl-1,5,6,7-tetrahydrocyclopenta[d]pyrimidine-2,4-dione is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transportation purposes. Packages must bear appropriate UN markings, proper shipping names, and hazard labels including GHS08 (health hazard) and GHS09 (environmental hazard) pictograms. Use approved packaging suitable for Packing Group III substances and ensure proper documentation accompanies shipments. Transport vehicles must comply with ADR regulations for Class 9 materials, and drivers require appropriate dangerous goods training certification.

3-cyclohexyl-1,5,6,7-tetrahydrocyclopenta[d]pyrimidine-2,4-dione is subject to multiple European regulations including REACH registration requirements and CLP classification obligations. The substance is classified as Carc. 2 (suspected carcinogen), Aquatic Acute 1, and Aquatic Chronic 1 under CLP regulation. While not currently listed as an SVHC, its carcinogenic classification may trigger authorization requirements in certain applications. Companies must ensure proper registration, safety data sheet provision, and workplace exposure controls. National occupational health regulations may impose additional handling and exposure monitoring requirements.

3-cyclohexyl-1,5,6,7-tetrahydrocyclopenta[d]pyrimidine-2,4-dione is available through OYSI, a specialized European distributor of fine chemicals and pharmaceutical intermediates. OYSI provides this compound to qualified industrial customers with proper handling capabilities for carcinogenic substances. Due to its hazardous classification, purchases typically require verification of appropriate safety measures and intended use documentation. Contact OYSI's technical team for product specifications, regulatory compliance support, and delivery arrangements throughout European markets while ensuring full regulatory compliance.