3,5-dichloro-2,6-difluoropyridin-4-amine

3,5-dichloro-2,6-difluoropyridin-4-amine is a halogenated pyridine derivative with the molecular formula C5H2Cl2F2N2 and CAS number 2840-00-8. This aromatic heterocyclic compound contains both chlorine and fluorine substituents on a pyridine ring with an amino group at position 4. With a molecular weight of 198.98 g/mol, it is classified as a moderate hazard chemical requiring appropriate safety precautions during handling and use.

3,5-dichloro-2,6-difluoropyridin-4-amine is a solid compound at room temperature with a molecular weight of 198.98 g/mol. As a halogenated aromatic amine, it typically exhibits limited water solubility due to its hydrophobic halogen substituents. The presence of multiple electron-withdrawing groups (chlorine and fluorine) significantly affects its chemical reactivity and stability. Specific physical properties such as melting point, boiling point, and exact solubility data should be confirmed through technical specifications.

3,5-dichloro-2,6-difluoropyridin-4-amine serves as an important intermediate in pharmaceutical and agrochemical synthesis. Its highly substituted pyridine structure makes it valuable for developing bioactive compounds, including potential drug candidates and crop protection chemicals. The compound's unique halogenation pattern provides specific reactivity for further chemical transformations. It is primarily used in research and development laboratories and specialized manufacturing facilities requiring advanced organic synthesis capabilities.

3,5-dichloro-2,6-difluoropyridin-4-amine requires careful handling due to its Acute Tox. 4 classification and GHS07 warning pictogram. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and appropriate respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and ensure proper training on chemical handling procedures. Always have emergency procedures readily available and maintain good hygiene practices after handling.

3,5-dichloro-2,6-difluoropyridin-4-amine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. As a halogenated compound, it should be kept separate from strong oxidizing agents and incompatible materials. Storage areas must be equipped with appropriate spill containment measures and maintained at stable temperatures. Regular container inspection is recommended to ensure integrity, and access should be restricted to trained personnel only.

Immediate action is required upon contact with 3,5-dichloro-2,6-difluoropyridin-4-amine due to its acute toxicity classification. For skin contact, immediately remove contaminated clothing and flush the affected area with plenty of water for at least 15 minutes. If eyes are affected, rinse thoroughly with clean water and seek medical attention promptly. In case of inhalation, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical care while providing the safety data sheet to healthcare professionals.

3,5-dichloro-2,6-difluoropyridin-4-amine must be disposed of as hazardous chemical waste according to local and national environmental regulations. The compound's Aquatic Chronic 2 classification and GHS09 pictogram indicate potential environmental hazards, requiring specialized disposal methods. Contact licensed hazardous waste disposal companies for proper treatment and destruction. Never dispose of this material through regular waste streams or discharge into sewers, soil, or waterways. Maintain proper documentation of all disposal activities for regulatory compliance.

3,5-dichloro-2,6-difluoropyridin-4-amine is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III, indicating moderate transport hazard. Packages must comply with appropriate ADR packaging requirements and display proper hazard labels and markings. Transport vehicles should carry necessary documentation including transport documents and emergency response information. Drivers must be trained in hazardous materials transport regulations. Ensure packages are properly secured and protected from damage during transit to prevent environmental release.

3,5-dichloro-2,6-difluoropyridin-4-amine is subject to standard European chemical regulations including REACH and CLP, but is not classified as a Substance of Very High Concern (SVHC). Users must comply with safety data sheet requirements, proper classification and labeling under CLP regulation, and appropriate risk assessment procedures. The compound's hazard classifications require adherence to occupational exposure limits and environmental protection measures. Regular regulatory monitoring is recommended as chemical legislation continues to evolve.

3,5-dichloro-2,6-difluoropyridin-4-amine is available through OYSI, a specialized European distributor of technical chemicals serving research institutions and industrial customers. OYSI provides this compound with appropriate documentation including certificates of analysis and safety data sheets compliant with European regulations. As a specialized chemical intermediate, availability may vary based on demand and production schedules. Contact OYSI directly for current availability, specifications, packaging options, and technical support for your specific application requirements.