2-chloro-6-(ethylamino)-4-nitrophenol

C8H9ClN2O3

CAS131657-78-8
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Warning

Consulting for 2-chloro-6-(ethylamino)-4-nitrophenol

Our experts support you with application, dosage, and compliance.

Request Consultation

Identification

CAS Number
131657-78-8
EC Number
411-440-1
UN Number
3077
Index Number
609-059-00-2
PubChem CID
9794399

Physical-chemical properties

Molecular Formula
C8H9ClN2O3
Molar Mass
216.62 g/mol
IUPAC Name
2-chloro-6-(ethylamino)-4-nitrophenol

Chemical Identifiers

InChI
InChI=1S/C8H9ClN2O3/c1-2-10-7-4-5(11(13)14)3-6(9)8(7)12/h3-4,10,12H,2H2,1H3
InChI Key
CDFNUSAXZDSXKF-UHFFFAOYSA-N

Overview

2-chloro-6-(ethylamino)-4-nitrophenol (CAS 131657-78-8) is a substituted phenolic compound with chlorine, nitro, and ethylamino functional groups providing specific chemical reactivity. This specialized chemical intermediate features a complex molecular structure with multiple reactive sites, making it valuable for various synthetic applications in the pharmaceutical and chemical industries. The compound's molecular formula C8H9ClN2O3 reflects the presence of chlorine, nitrogen-containing groups, and a phenolic backbone, which contribute to its unique chemical behavior and industrial utility. The substance presents moderate toxicity concerns, classified as Acute Tox. 4 with skin sensitization properties (Skin Sens. 1), requiring appropriate handling procedures and personal protective equipment during industrial use. Its aquatic chronic toxicity classification (Aquatic Chronic 2) necessitates careful environmental management practices. The Warning signal word and associated GHS07 and GHS09 pictograms indicate the need for standard industrial safety protocols. In industrial applications, 2-chloro-6-(ethylamino)-4-nitrophenol serves primarily as a chemical intermediate in organic synthesis processes. Its multi-functional structure makes it particularly useful in pharmaceutical research and development, where compounds with similar complexity, such as 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one, are employed for advanced synthetic transformations. The compound also finds application in specialty chemical manufacturing and research laboratories requiring precise molecular building blocks. The substance's classification under ADR Class 9 facilitates its transportation within European markets, supporting efficient supply chain management for industrial customers requiring specialized chemical intermediates. OYSI maintains reliable supply capabilities for 2-chloro-6-(ethylamino)-4-nitrophenol, supporting European industrial customers with consistent availability and technical expertise for specialized chemical requirements.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; Skin Sens. 1; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

H317

May cause an allergic skin reaction.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name2-Chlor-6-(ethylamino)-4-nitrophenol
Marine PollutantNo

Frequently Asked Questions

What is 2-chloro-6-(ethylamino)-4-nitrophenol?

2-chloro-6-(ethylamino)-4-nitrophenol is an organic chemical compound with the molecular formula C8H9ClN2O3 and CAS number 131657-78-8. This substituted phenol contains chlorine, ethylamino, and nitro functional groups, giving it a molecular weight of 216.62 g/mol. It is classified as a hazardous substance with moderate acute toxicity, skin sensitizing properties, and chronic aquatic toxicity. The compound requires careful handling due to its chemical structure and associated safety classifications.

What are the physicochemical properties of 2-chloro-6-(ethylamino)-4-nitrophenol?

2-chloro-6-(ethylamino)-4-nitrophenol is a solid organic compound at room temperature with a molecular weight of 216.62 g/mol. The presence of phenolic hydroxyl, nitro, chloro, and ethylamino substituents influences its solubility and reactivity characteristics. As a substituted nitrophenol, it likely exhibits limited water solubility but may dissolve in organic solvents. The specific physical properties such as melting point, boiling point, and exact appearance should be confirmed through technical documentation for precise applications.

What is 2-chloro-6-(ethylamino)-4-nitrophenol used for?

2-chloro-6-(ethylamino)-4-nitrophenol serves as an intermediate in organic synthesis and pharmaceutical manufacturing processes. The compound's structure with multiple functional groups makes it valuable for creating more complex molecules through chemical transformations. It may be used in the production of dyes, pharmaceuticals, or specialty chemicals where its specific substitution pattern is required. Industrial applications typically involve controlled manufacturing environments due to its hazardous classification and the need for specialized handling procedures.

How to handle 2-chloro-6-(ethylamino)-4-nitrophenol safely?

2-chloro-6-(ethylamino)-4-nitrophenol requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume extraction systems to prevent inhalation exposure. Avoid direct skin contact as the compound is classified as a skin sensitizer. Use proper handling techniques to prevent spills and ensure emergency washing facilities are readily available. Follow established chemical safety protocols and maintain safety data sheets accessible to all personnel handling this material.

How to store 2-chloro-6-(ethylamino)-4-nitrophenol correctly?

2-chloro-6-(ethylamino)-4-nitrophenol should be stored in tightly closed containers in a cool, dry, and well-ventilated area away from heat sources and incompatible materials. Keep containers sealed when not in use to prevent contamination and degradation. Store away from strong oxidizers and reducing agents that could react with the nitro and amino functional groups. Maintain proper labeling and ensure storage areas comply with local chemical storage regulations. Regular inventory checks help monitor container integrity and material condition.

What to do in case of contact with 2-chloro-6-(ethylamino)-4-nitrophenol?

Immediate action is required upon contact with 2-chloro-6-(ethylamino)-4-nitrophenol due to its skin sensitizing and toxic properties. For skin contact, immediately remove contaminated clothing and wash affected areas thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush with clean water for at least 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention if symptoms develop or exposure is significant. Never induce vomiting if ingested and consult medical professionals promptly.

How to dispose of 2-chloro-6-(ethylamino)-4-nitrophenol appropriately?

2-chloro-6-(ethylamino)-4-nitrophenol must be disposed of according to local and national hazardous waste regulations due to its toxic and environmentally harmful classification. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never dispose of this material through regular waste streams or sewage systems due to its Aquatic Chronic 2 classification. Maintain proper documentation of disposal activities and ensure containers are properly labeled until final disposal. Small quantities may require special collection procedures through authorized waste management services.

How to transport 2-chloro-6-(ethylamino)-4-nitrophenol?

2-chloro-6-(ethylamino)-4-nitrophenol is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to international transport regulations. Use UN-specification packaging suitable for Class 9 materials and ensure proper hazard labels are affixed. Transport documents must include the correct shipping name, UN number, and hazard class. Only authorized personnel should handle transportation arrangements to ensure compliance with ADR/RID regulations for road and rail transport.

Is 2-chloro-6-(ethylamino)-4-nitrophenol subject to specific regulations?

2-chloro-6-(ethylamino)-4-nitrophenol is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The compound is not currently listed as a Substance of Very High Concern (SVHC) under REACH. Its hazard classification requires compliance with workplace safety regulations, environmental protection measures, and proper risk assessment procedures. Users must maintain safety data sheets, implement appropriate risk management measures, and ensure worker training on safe handling procedures. Regular regulatory updates should be monitored for any changes in classification or restrictions.

Where to buy 2-chloro-6-(ethylamino)-4-nitrophenol in Europe?

2-chloro-6-(ethylamino)-4-nitrophenol is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides reliable supply chains for industrial customers requiring this compound for manufacturing and research applications. As a professional chemical distributor, OYSI ensures proper handling, documentation, and regulatory compliance for European markets. Contact OYSI directly for availability, specifications, and delivery options suited to your specific industrial requirements. Professional technical support and safety documentation are provided with all chemical supplies.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.