1,10-phenanthroline

C12H8N2

CAS66-71-7
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
66-71-7
EC Number
200-629-2
UN Number
2811
Index Number
613-092-00-8
PubChem CID
1318

Physical-chemical properties

Molecular Formula
C12H8N2
Molar Mass
180.20 g/mol
IUPAC Name
1,10-phenanthroline

Chemical Identifiers

InChI
InChI=1S/C12H8N2/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1/h1-8H
InChI Key
DGEZNRSVGBDHLK-UHFFFAOYSA-N

Overview

1,10-Phenanthroline (CAS 66-71-7) is a heterocyclic organic compound with strong metal-chelating properties and applications in analytical chemistry and research. This nitrogen-containing aromatic compound serves as a versatile chelating agent widely recognized for its ability to form stable complexes with various metal ions, particularly iron(II). As a bidentate ligand, 1,10-phenanthroline features two nitrogen atoms positioned to coordinate effectively with metal centers, making it invaluable in both analytical and synthetic applications. The compound exhibits characteristic fluorescent properties and demonstrates excellent selectivity for specific metal ions under controlled conditions. From a safety perspective, 1,10-phenanthroline requires careful handling due to its acute toxicity classification (Acute Tox. 3) and significant environmental concerns, as indicated by its aquatic toxicity ratings (Aquatic Acute 1, Aquatic Chronic 1). The presence of GHS06 and GHS09 pictograms emphasizes both the health hazards and environmental risks associated with improper handling. Transportation falls under ADR Class 6.1, reflecting its toxic nature and requiring appropriate safety protocols during shipping and storage. Industrial applications primarily focus on analytical chemistry, where 1,10-phenanthroline functions as a colorimetric reagent for iron determination in water analysis and metallurgy. The compound also finds use in coordination chemistry research and as a building block for advanced materials synthesis. Unlike structurally different compounds such as (2-propan-2-yloxyphenyl) N-methylcarbamate, which serves different industrial purposes, 1,10-phenanthroline's unique aromatic structure provides specific chelation characteristics essential for precision analytical work. OYSI supplies high-quality 1,10-phenanthroline to European customers, supporting diverse analytical and research applications across multiple industries with reliable technical support and regulatory compliance.

Safety & Classification

Danger
Classification:

Acute Tox. 3 *; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H301

Toxic if swallowed.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2811
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping Name1,10-Phenanthrolin
Marine PollutantNo

Frequently Asked Questions

What is 1,10-phenanthroline?

1,10-phenanthroline is an organic heterocyclic compound with the molecular formula C12H8N2 and CAS number 66-71-7. This aromatic compound consists of three fused benzene rings with two nitrogen atoms positioned at the 1 and 10 positions. With a molecular weight of 180.2 g/mol, it serves as an important chelating agent and analytical reagent in various chemical applications.

What are the physicochemical properties of 1,10-phenanthroline?

1,10-phenanthroline is a white to pale yellow crystalline solid at room temperature. It exhibits poor solubility in water but dissolves readily in organic solvents such as ethanol and chloroform. The compound is odorless and has a melting point around 117°C. Its planar aromatic structure allows it to form stable complexes with metal ions through coordination bonding.

What is 1,10-phenanthroline used for?

1,10-phenanthroline is primarily used as a chelating agent and analytical reagent in laboratory settings. It serves as a colorimetric indicator for iron determination, forming distinctive red complexes with Fe2+ ions. The compound is also utilized in coordination chemistry research, as a ligand in metal complex synthesis, and in electrochemical applications. Additionally, it finds use in pharmaceutical research and environmental analysis.

How to handle 1,10-phenanthroline safely?

1,10-phenanthroline must be handled with appropriate personal protective equipment due to its Acute Tox. 3 classification. Wear chemical-resistant gloves, safety goggles, and protective clothing when handling. Work in well-ventilated areas or under fume hoods to avoid inhalation. Avoid skin and eye contact, and prevent ingestion. The GHS06 pictogram indicates acute toxicity hazards, requiring careful handling procedures and emergency response preparedness.

How to store 1,10-phenanthroline correctly?

1,10-phenanthroline should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers tightly sealed to prevent moisture absorption and contamination. Store separately from incompatible materials such as strong oxidizing agents. Maintain storage temperatures below 25°C and ensure proper labeling with hazard information. Regular inventory checks should be conducted to monitor container integrity.

What to do in case of contact with 1,10-phenanthroline?

In case of skin contact with 1,10-phenanthroline, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention.

How to dispose of 1,10-phenanthroline appropriately?

1,10-phenanthroline waste must be disposed of according to local and national hazardous waste regulations due to its toxicity and environmental hazard classification. Contact licensed hazardous waste disposal companies for proper treatment. Do not discharge into drains, soil, or water bodies as it poses risks to aquatic environments (Aquatic Acute 1, Aquatic Chronic 1). Maintain proper waste documentation and follow facility-specific disposal protocols.

How to transport 1,10-phenanthroline?

1,10-phenanthroline is classified as ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. It requires appropriate UN specification packaging and hazard labeling during transport. Shipping documentation must include proper shipping names, hazard classes, and emergency contact information. Transport vehicles must carry appropriate emergency equipment and drivers need ADR training certification for toxic substance transport.

Is 1,10-phenanthroline subject to specific regulations?

1,10-phenanthroline is subject to CLP regulation requirements for classification, labeling, and packaging due to its hazardous properties. It falls under REACH registration obligations for importers and manufacturers. While not currently listed as an SVHC substance, its acute toxicity and environmental hazard classifications require compliance with occupational safety regulations and environmental protection measures across EU member states.

Where to buy 1,10-phenanthroline in Europe?

1,10-phenanthroline is available through OYSI, a European chemical distributor specializing in technical and laboratory chemicals. OYSI provides this compound to laboratories, research institutions, and industrial customers across Europe with proper documentation and safety data sheets. Contact OYSI's sales team for availability, packaging options, and delivery information to your specific location within Europe.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.