4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol

C23H28O4

CAS40278-59-9
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt

Consulting for 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol

Our experts support you with application, dosage, and compliance.

Request Consultation

Identification

CAS Number
40278-59-9
EC Number
400-270-3
UN Number
3077
Index Number
604-026-00-9
PubChem CID
10937491

Physical-chemical properties

Molecular Formula
C23H28O4
Molar Mass
368.50 g/mol
IUPAC Name
4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol

Chemical Identifiers

InChI
InChI=1S/C23H28O4/c1-13-7-19-15(9-17(13)24)21(3,4)11-23(26-19)12-22(5,6)16-10-18(25)14(2)8-20(16)27-23/h7-10,24-25H,11-12H2,1-6H3
InChI Key
HPPJCHQXOCLCJJ-UHFFFAOYSA-N

Overview

4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol (CAS 40278-59-9) is an organic spirocompound featuring dual chromene rings with hydroxyl functionalities and extensive methylation. This specialized spirobi[chromene] derivative represents a sophisticated molecular architecture characterized by its unique spiro carbon center linking two chromene ring systems. With a molecular formula of C23H28O4 and molecular weight of 368.5 g/mol, this compound exhibits distinctive structural features including six methyl substituents and two hydroxyl groups positioned at the 6,6'-positions of the chromene rings. The extensive methylation pattern contributes to its chemical stability and influences its solubility characteristics. From a safety perspective, this compound is classified under Aquatic Chronic 2 hazard category, requiring appropriate environmental precautions during handling and disposal. The GHS09 pictogram indicates potential environmental hazards, while its ADR Class 9 classification designates it as a miscellaneous dangerous substance for transport purposes. Despite these classifications, no specific signal word is required, suggesting moderate hazard levels under proper handling conditions. Industrial applications typically involve its use as an intermediate in specialty chemical synthesis, particularly in the development of optical materials and advanced polymer systems. The compound's chromene backbone structure makes it valuable in photochemical applications and as a building block for more complex molecular architectures. Related compounds such as N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide share similar applications in specialty chemical manufacturing, though with different structural frameworks. OYSI maintains strategic inventory levels of this specialized spirobi[chromene] compound to support European industrial customers requiring reliable access to high-quality specialty chemicals.

Safety & Classification

Classification:

Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name2,2'-Spirobi(6-hydroxy-4,4,7-trimethylchroman)
Marine PollutantNo

Frequently Asked Questions

What is 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol?

4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol is an organic chemical compound with the molecular formula C23H28O4 and CAS number 40278-59-9. This substance belongs to the chromene family and features a spiro structure with two chromene rings connected through a central carbon atom. With a molecular weight of 368.5 g/mol, it contains hydroxyl groups and multiple methyl substituents that influence its chemical properties and potential applications.

What are the physicochemical properties of 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol?

4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol is a solid organic compound at room temperature with a molecular weight of 368.5 g/mol. The presence of hydroxyl groups and the spiro-chromene structure suggest limited water solubility but good solubility in organic solvents. The multiple methyl groups provide steric hindrance and influence its reactivity. Specific physical properties such as melting point, boiling point, and exact solubility values would require analytical characterization for precise determination.

What is 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol used for?

4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol is primarily used in specialized chemical applications where its unique spiro-chromene structure provides specific properties. Its applications may include use as an intermediate in organic synthesis, research and development projects, or as a component in specialized formulations. The presence of hydroxyl groups and the rigid spiro structure make it valuable for applications requiring specific molecular geometry and reactivity patterns in industrial chemistry processes.

How to handle 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol safely?

4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol should be handled with standard laboratory safety precautions including wearing appropriate personal protective equipment such as safety glasses, gloves, and lab coats. Work in well-ventilated areas or under fume hoods to avoid inhalation. Although no specific GHS signal word is assigned, the compound's classification as Aquatic Chronic 2 indicates environmental precautions are necessary. Avoid release to the environment and follow good industrial hygiene practices during handling operations.

How to store 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol correctly?

4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. The storage area should be protected from moisture to prevent degradation of the compound. Keep containers properly labeled and store away from incompatible materials. Due to its Aquatic Chronic 2 classification, ensure storage areas have appropriate containment measures to prevent environmental release in case of spills or container damage.

What to do in case of contact with 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol?

In case of skin contact with 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol, immediately wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, rinse thoroughly with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet for specific first aid measures and contact emergency services if severe symptoms occur.

How to dispose of 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol appropriately?

4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol must be disposed of according to local and national environmental regulations due to its Aquatic Chronic 2 classification. Do not dispose of in regular waste streams or discharge into sewers, waterways, or soil. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may be suitable for incineration at authorized facilities with appropriate emission controls. Always consult local environmental authorities for specific disposal requirements in your region.

How to transport 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol?

4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to ADR regulations. Use UN-approved packaging suitable for Packing Group III substances. Vehicles must display appropriate placards and drivers require ADR certification. Transport documents must include proper shipping names, UN numbers, and hazard classifications. Ensure compliance with all applicable transport regulations for dangerous goods.

Is 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol subject to specific regulations?

4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol is subject to REACH regulation in Europe and must comply with CLP classification requirements, displaying GHS09 environmental hazard pictogram. The substance is classified as Aquatic Chronic 2 under CLP, requiring appropriate environmental risk management measures. It is not currently listed as a Substance of Very High Concern (SVHC). Users must ensure compliance with occupational health and safety regulations and environmental protection laws in their respective countries.

Where to buy 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol in Europe?

4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol is available through OYSI, a specialized European distributor of technical chemical products. OYSI provides professional chemical supply services with proper documentation, safety data sheets, and regulatory compliance support. As a specialized compound, availability may be subject to minimum order quantities and lead times. Contact OYSI directly for current availability, technical specifications, and pricing information to meet your specific application requirements in the European market.

Services for 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol

ADR Consulting for 4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol

4,4,4',4',7,7'-hexamethyl-2,2'-spirobi[3H-chromene]-6,6'-diol is a dangerous good. We support you with labeling, packaging, and transport documentation.

Request ADR Advice

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.