2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one
C15H13Cl2N3O2
Consulting for 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one
Our experts support you with application, dosage, and compliance.
Identification
- CAS Number
- 68049-83-2
- UN Number
- 3077
- Index Number
- 611-140-00-2
- PubChem CID
- 443029
Physical-chemical properties
- Molecular Formula
- C15H13Cl2N3O2
- Molar Mass
- 338.20 g/mol
- IUPAC Name
- 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one
Chemical Identifiers
- InChI
- InChI=1S/C15H13Cl2N3O2/c1-2-7-22-13-9-12(10(16)8-11(13)17)20-15(21)19-6-4-3-5-14(19)18-20/h1,8-9H,3-7H2
- InChI Key
- XOEMATDHVZOBSG-UHFFFAOYSA-N
Overview
2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one (CAS 68049-83-2) is a specialized heterocyclic compound featuring dichlorophenyl and triazolopyridinone structural elements with significant biological activity potential. This complex organic molecule represents a sophisticated example of modern synthetic chemistry, combining multiple functional groups including dichlorinated aromatic rings, propargyl ether linkages, and fused triazolo-pyridinone systems. With a molecular formula of C15H13Cl2N3O2 and molecular weight of 338.2 g/mol, this compound demonstrates the intricate molecular architecture typical of advanced pharmaceutical intermediates and specialty chemicals. The substance exhibits significant safety considerations, classified as Repr. 1B (reproductive toxicity), STOT RE 2 (specific target organ toxicity), and presents notable aquatic toxicity concerns with both acute and chronic classifications. The GHS08 and GHS09 pictograms reflect its health and environmental hazard profile, requiring careful handling protocols and appropriate containment measures during storage and processing. Industrial applications primarily focus on pharmaceutical research and development, where its unique triazolopyridinone structure serves as a valuable building block for drug discovery programs. The compound also finds utility in agrochemical synthesis and as an intermediate in the production of specialized bioactive molecules. Unlike simpler aromatic compounds such as 4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline, this molecule's heterocyclic complexity enables more specific biological interactions. Transportation under ADR Class 9 classification ensures appropriate handling during logistics operations, while its specialized nature requires expert technical support throughout the supply chain. OYSI maintains reliable access to this specialized compound through our established network of qualified manufacturers, supporting European customers with comprehensive technical documentation and regulatory compliance assistance.
Safety & Classification
Repr. 1B; STOT RE 2 *; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Transport (ADR)
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | Azafenidin |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one?
2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one is an organic compound with molecular formula C15H13Cl2N3O2 and molecular weight 338.2 g/mol. This heterocyclic compound contains both triazole and pyridine ring systems with chlorinated aromatic substituents. It is classified as a reproductive toxin category 1B and poses environmental hazards to aquatic ecosystems.
What are the physicochemical properties of 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one?
This compound is a solid crystalline substance at room temperature with a molecular weight of 338.2 g/mol. The presence of chlorine atoms and heterocyclic rings influences its polarity and solubility characteristics. The triazolo-pyridine structure contributes to its stability under normal conditions. Specific physical properties such as melting point, boiling point, and exact solubility data should be obtained from the safety data sheet for precise handling requirements.
What is 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one used for?
This compound is primarily used in pharmaceutical research and development as an intermediate or active pharmaceutical ingredient. Its complex heterocyclic structure makes it valuable in medicinal chemistry applications. The triazolo-pyridine framework is commonly found in bioactive molecules with potential therapeutic properties. Professional use is recommended due to its reproductive toxicity classification and environmental impact concerns.
How to handle 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one safely?
Safe handling requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Repr. 1B classification. Work in well-ventilated areas or under fume hood to prevent inhalation exposure. Avoid skin contact and ingestion. Use GHS08 and GHS09 pictogram warnings as guidance. Implement engineering controls and follow STOT RE 2 precautions to prevent repeated exposure that could cause organ damage.
How to store 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one correctly?
Store this compound in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Use tightly sealed containers to prevent moisture absorption and contamination. Separate from oxidizing agents and reactive chemicals. Implement appropriate containment measures to prevent environmental release due to its Aquatic Acute 1 and Chronic 1 classifications. Ensure storage areas are equipped with spill containment and emergency response materials.
What to do in case of contact with 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one?
Immediate decontamination is essential following any contact. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush with clean water for 15-20 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. Seek medical attention promptly, especially considering the reproductive toxicity classification, and provide the safety data sheet to medical personnel.
How to dispose of 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one appropriately?
Disposal must comply with local and European waste regulations due to its hazardous classification. This compound requires treatment as hazardous waste and cannot be disposed of in regular waste streams. Contact licensed hazardous waste disposal companies for proper treatment. Prevent environmental release due to aquatic toxicity concerns. Incineration at authorized facilities may be required. Never dispose of via sewage systems or general waste collection.
How to transport 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one?
Transportation follows ADR Class 9 regulations as a miscellaneous dangerous substance, Packing Group III. Use appropriate packaging that meets UN specification requirements for Class 9 materials. Ensure proper labeling with GHS08 and GHS09 pictograms and hazard information. Transport documentation must include proper shipping names and hazard classifications. Drivers require appropriate ADR training and vehicles must comply with Class 9 transport requirements.
Is 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one subject to specific regulations?
This compound is subject to REACH regulation requiring registration for import/manufacture above 1 tonne annually. CLP regulation applies for classification as Repr. 1B, STOT RE 2, and aquatic hazard categories. While not currently an SVHC, its reproductive toxicity classification means it may face future restrictions. Users must comply with occupational exposure limits and implement risk management measures. Professional use restrictions may apply due to its hazard profile.
Where to buy 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one in Europe?
OYSI serves as a reliable European distributor for this specialized chemical compound, providing quality products with proper documentation and regulatory compliance. As a professional chemical supplier, OYSI ensures appropriate packaging, labeling, and safety data sheet provision. Contact OYSI directly for availability, specifications, and ordering information. Due to the compound's hazard classification, sales are typically restricted to qualified professional users with appropriate handling capabilities and regulatory compliance.
Services for 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one
Order 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one
Fast delivery across Europe
SDS Service
Request Safety Data Sheet for 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one
Technical Consulting
Application advice for 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one
REACH Safety Data Sheet
REACH Compliance Service
Digital Product Passport
EU-compliant product documentation
ADR Consulting for 2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one
2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.